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Items: 1 to 20 of 130

1.

Inhibition of monocyte chemotaxis by VB-201, a small molecule lecinoxoid, hinders atherosclerosis development in ApoE⁻/⁻ mice.

Feige E, Yacov N, Salem Y, Levi I, Mendel I, Propheta-Meiran O, Shoham A, Hait-Darshan R, Polonsky O, George J, Harats D, Breitbart E.

Atherosclerosis. 2013 Aug;229(2):430-9. doi: 10.1016/j.atherosclerosis.2013.06.005. Epub 2013 Jun 21.

2.

Oxidized phospholipids trigger atherogenic inflammation in murine arteries.

Furnkranz A, Schober A, Bochkov VN, Bashtrykov P, Kronke G, Kadl A, Binder BR, Weber C, Leitinger N.

Arterioscler Thromb Vasc Biol. 2005 Mar;25(3):633-8. Epub 2004 Dec 9.

3.

VB-201, an oxidized phospholipid small molecule, inhibits CD14- and Toll-like receptor-2-dependent innate cell activation and constrains atherosclerosis.

Mendel I, Feige E, Yacov N, Salem Y, Levi I, Propheta-Meiran O, Shoham A, Ishai E, George J, Harats D, Breitbart E.

Clin Exp Immunol. 2014 Jan;175(1):126-37. doi: 10.1111/cei.12212.

4.

Platelets mediate oxidized low-density lipoprotein-induced monocyte extravasation and foam cell formation.

Badrnya S, Schrottmaier WC, Kral JB, Yaiw KC, Volf I, Schabbauer G, Söderberg-Nauclér C, Assinger A.

Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):571-80. doi: 10.1161/ATVBAHA.113.302919. Epub 2013 Dec 26.

5.

Pharmacological inhibition of the chemokine receptor, CX3CR1, reduces atherosclerosis in mice.

Poupel L, Boissonnas A, Hermand P, Dorgham K, Guyon E, Auvynet C, Charles FS, Lesnik P, Deterre P, Combadiere C.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2297-305. doi: 10.1161/ATVBAHA.112.300930. Epub 2013 Jul 25.

6.

Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils.

Leitinger N, Tyner TR, Oslund L, Rizza C, Subbanagounder G, Lee H, Shih PT, Mackman N, Tigyi G, Territo MC, Berliner JA, Vora DK.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12010-5.

7.

Induction of CCR2-dependent macrophage accumulation by oxidized phospholipids in the air-pouch model of inflammation.

Kadl A, Galkina E, Leitinger N.

Arthritis Rheum. 2009 May;60(5):1362-71. doi: 10.1002/art.24448.

8.

Paraoxonase-1 reduces monocyte chemotaxis and adhesion to endothelial cells due to oxidation of palmitoyl, linoleoyl glycerophosphorylcholine.

Ahmed Z, Babaei S, Maguire GF, Draganov D, Kuksis A, La Du BN, Connelly PW.

Cardiovasc Res. 2003 Jan;57(1):225-31.

9.

Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression.

Horio E, Kadomatsu T, Miyata K, Arai Y, Hosokawa K, Doi Y, Ninomiya T, Horiguchi H, Endo M, Tabata M, Tazume H, Tian Z, Takahashi O, Terada K, Takeya M, Hao H, Hirose N, Minami T, Suda T, Kiyohara Y, Ogawa H, Kaikita K, Oike Y.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):790-800. doi: 10.1161/ATVBAHA.113.303116. Epub 2014 Feb 13.

10.

Hydroxy alkenal phospholipids regulate inflammatory functions of endothelial cells.

Subbanagounder G, Deng Y, Borromeo C, Dooley AN, Berliner JA, Salomon RG.

Vascul Pharmacol. 2002 Apr;38(4):201-9.

PMID:
12449016
11.

PKCβ promotes vascular inflammation and acceleration of atherosclerosis in diabetic ApoE null mice.

Kong L, Shen X, Lin L, Leitges M, Rosario R, Zou YS, Yan SF.

Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1779-87. doi: 10.1161/ATVBAHA.112.301113. Epub 2013 Jun 13.

12.

High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory.

Gharavi NM, Gargalovic PS, Chang I, Araujo JA, Clark MJ, Szeto WL, Watson AD, Lusis AJ, Berliner JA.

Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1346-53. Epub 2007 Mar 22.

13.

Mitogen-activated protein kinase phosphatase 1 activity is necessary for oxidized phospholipids to induce monocyte chemotactic activity in human aortic endothelial cells.

Reddy S, Hama S, Grijalva V, Hassan K, Mottahedeh R, Hough G, Wadleigh DJ, Navab M, Fogelman AM.

J Biol Chem. 2001 May 18;276(20):17030-5. Epub 2001 Mar 5.

14.

Postprandial lipoproteins and the molecular regulation of vascular homeostasis.

Botham KM, Wheeler-Jones CP.

Prog Lipid Res. 2013 Oct;52(4):446-64. doi: 10.1016/j.plipres.2013.06.001. Epub 2013 Jun 15. Review.

PMID:
23774609
15.

Early inflammatory reactions in atherosclerosis are induced by proline-rich tyrosine kinase/reactive oxygen species-mediated release of tumor necrosis factor-alpha and subsequent activation of the p21Cip1/Ets-1/p300 system.

Katsume A, Okigaki M, Matsui A, Che J, Adachi Y, Kishita E, Yamaguchi S, Ikeda K, Ueyama T, Matoba S, Yamada H, Matsubara H.

Arterioscler Thromb Vasc Biol. 2011 May;31(5):1084-92. doi: 10.1161/ATVBAHA.110.221804. Epub 2011 Mar 3. Retraction in: Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):e6.

17.

Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism.

McGraw AP, Bagley J, Chen WS, Galayda C, Nickerson H, Armani A, Caprio M, Carmeliet P, Jaffe IZ.

J Am Heart Assoc. 2013 Feb 22;2(1):e000018. doi: 10.1161/JAHA.112.000018.

18.

Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo.

Watson AD, Leitinger N, Navab M, Faull KF, Hörkkö S, Witztum JL, Palinski W, Schwenke D, Salomon RG, Sha W, Subbanagounder G, Fogelman AM, Berliner JA.

J Biol Chem. 1997 May 23;272(21):13597-607.

19.

Sphingosine-1-phosphate receptor 3 promotes recruitment of monocyte/macrophages in inflammation and atherosclerosis.

Keul P, Lucke S, von Wnuck Lipinski K, Bode C, Gräler M, Heusch G, Levkau B.

Circ Res. 2011 Feb 4;108(3):314-23. doi: 10.1161/CIRCRESAHA.110.235028. Epub 2010 Dec 16.

20.

Molecular mechanisms of irbesartan suppressing atherosclerosis in high cholesterol-diet apolipoprotein E knock-out mice.

Yao R, Cheng X, Chen Y, Xie JJ, Yu X, Liao MY, Ding YJ, Tang TT, Liao YH.

Int J Cardiol. 2010 Mar 4;139(2):113-22. doi: 10.1016/j.ijcard.2008.10.013. Epub 2008 Nov 22. Erratum in: Int J Cardiol. 2014 Dec 20;177(3):1146-8.

PMID:
19028402
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