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Results: 1 to 20 of 353

1.

Ca2+/calmodulin-dependent protein kinase II and protein kinase A differentially regulate sarcoplasmic reticulum Ca2+ leak in human cardiac pathology.

Fischer TH, Herting J, Tirilomis T, Renner A, Neef S, Toischer K, Ellenberger D, Förster A, Schmitto JD, Gummert J, Schöndube FA, Hasenfuss G, Maier LS, Sossalla S.

Circulation. 2013 Aug 27;128(9):970-81. doi: 10.1161/CIRCULATIONAHA.113.001746. Epub 2013 Jul 19.

PMID:
23877259
[PubMed - indexed for MEDLINE]
Free Article
2.

Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure.

Ai X, Curran JW, Shannon TR, Bers DM, Pogwizd SM.

Circ Res. 2005 Dec 9;97(12):1314-22. Epub 2005 Nov 3.

PMID:
16269653
[PubMed - indexed for MEDLINE]
Free Article
3.

CaMKII-dependent diastolic SR Ca2+ leak and elevated diastolic Ca2+ levels in right atrial myocardium of patients with atrial fibrillation.

Neef S, Dybkova N, Sossalla S, Ort KR, Fluschnik N, Neumann K, Seipelt R, Schöndube FA, Hasenfuss G, Maier LS.

Circ Res. 2010 Apr 2;106(6):1134-44. doi: 10.1161/CIRCRESAHA.109.203836. Epub 2010 Jan 7.

PMID:
20056922
[PubMed - indexed for MEDLINE]
Free Article
4.

Effect of metoprolol on sarcoplasmic reticulum Ca2+ leak in a rabbit model of heart failure.

Zhang SJ, Liu ZH, Zou C, Wang L.

Chin Med J (Engl). 2012 Mar;125(5):815-22.

PMID:
22490580
[PubMed - indexed for MEDLINE]
5.

Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.

Curran J, Hinton MJ, Ríos E, Bers DM, Shannon TR.

Circ Res. 2007 Feb 16;100(3):391-8. Epub 2007 Jan 18.

PMID:
17234966
[PubMed - indexed for MEDLINE]
Free Article
6.

Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation.

Voigt N, Li N, Wang Q, Wang W, Trafford AW, Abu-Taha I, Sun Q, Wieland T, Ravens U, Nattel S, Wehrens XH, Dobrev D.

Circulation. 2012 May 1;125(17):2059-70. doi: 10.1161/CIRCULATIONAHA.111.067306. Epub 2012 Mar 28.

PMID:
22456474
[PubMed - indexed for MEDLINE]
Free Article
7.

Role of RyR2 phosphorylation at S2814 during heart failure progression.

Respress JL, van Oort RJ, Li N, Rolim N, Dixit SS, deAlmeida A, Voigt N, Lawrence WS, Skapura DG, Skårdal K, Wisløff U, Wieland T, Ai X, Pogwizd SM, Dobrev D, Wehrens XH.

Circ Res. 2012 May 25;110(11):1474-83. doi: 10.1161/CIRCRESAHA.112.268094. Epub 2012 Apr 17.

PMID:
22511749
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during beta-adrenergic stimulation.

Ferrero P, Said M, Sánchez G, Vittone L, Valverde C, Donoso P, Mattiazzi A, Mundiña-Weilenmann C.

J Mol Cell Cardiol. 2007 Sep;43(3):281-91. Epub 2007 Jun 6.

PMID:
17643448
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca2+ leak in mouse heart.

Morimoto S, O-Uchi J, Kawai M, Hoshina T, Kusakari Y, Komukai K, Sasaki H, Hongo K, Kurihara S.

Biochem Biophys Res Commun. 2009 Dec 4;390(1):87-92. doi: 10.1016/j.bbrc.2009.09.071. Epub 2009 Sep 23.

PMID:
19781523
[PubMed - indexed for MEDLINE]
10.

Differences in sarcoplasmic reticulum Ca2+ leak characteristics between systolic and diastolic heart failure rabbit models.

Wang L, Zhang S, Zou C, Liu Z.

Chin J Physiol. 2011 Apr 30;54(2):133-42.

PMID:
21789895
[PubMed - indexed for MEDLINE]
11.

JTV519 (K201) reduces sarcoplasmic reticulum Ca²⁺ leak and improves diastolic function in vitro in murine and human non-failing myocardium.

Sacherer M, Sedej S, Wakuła P, Wallner M, Vos MA, Kockskämper J, Stiegler P, Sereinigg M, von Lewinski D, Antoons G, Pieske BM, Heinzel FR; CONTICA investigators.

Br J Pharmacol. 2012 Oct;167(3):493-504. doi: 10.1111/j.1476-5381.2012.01995.x.

PMID:
22509897
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Oxidation- and CaMKII-mediated sarcoplasmic reticulum Ca(2+) leak triggers atrial fibrillation in aging.

Guo X, Yuan S, Liu Z, Fang Q.

J Cardiovasc Electrophysiol. 2014 Jun;25(6):645-52. doi: 10.1111/jce.12395. Epub 2014 May 2.

PMID:
24576293
[PubMed - indexed for MEDLINE]
13.

Increased intracellular Ca2+ and SR Ca2+ load contribute to arrhythmias after acidosis in rat heart. Role of Ca2+/calmodulin-dependent protein kinase II.

Said M, Becerra R, Palomeque J, Rinaldi G, Kaetzel MA, Diaz-Sylvester PL, Copello JA, Dedman JR, Mundiña-Weilenmann C, Vittone L, Mattiazzi A.

Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1669-83. doi: 10.1152/ajpheart.00010.2008. Epub 2008 Aug 22.

PMID:
18723772
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Role of chronic ryanodine receptor phosphorylation in heart failure and β-adrenergic receptor blockade in mice.

Shan J, Betzenhauser MJ, Kushnir A, Reiken S, Meli AC, Wronska A, Dura M, Chen BX, Marks AR.

J Clin Invest. 2010 Dec;120(12):4375-87. doi: 10.1172/JCI37649. Epub 2010 Nov 22.

PMID:
21099115
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice.

Zhang T, Guo T, Mishra S, Dalton ND, Kranias EG, Peterson KL, Bers DM, Brown JH.

Circ Res. 2010 Feb 5;106(2):354-62. doi: 10.1161/CIRCRESAHA.109.207423. Epub 2009 Dec 3.

PMID:
19959778
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The relationship between arrhythmogenesis and impaired contractility in heart failure: role of altered ryanodine receptor function.

Belevych AE, Terentyev D, Terentyeva R, Nishijima Y, Sridhar A, Hamlin RL, Carnes CA, Györke S.

Cardiovasc Res. 2011 Jun 1;90(3):493-502. doi: 10.1093/cvr/cvr025. Epub 2011 Jan 27.

PMID:
21273243
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Cardiac ryanodine receptor phosphorylation by CaM Kinase II: keeping the balance right.

Currie S.

Front Biosci (Landmark Ed). 2009 Jun 1;14:5134-56. Review.

PMID:
19482609
[PubMed - indexed for MEDLINE]
18.

Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure.

Sag CM, Wadsack DP, Khabbazzadeh S, Abesser M, Grefe C, Neumann K, Opiela MK, Backs J, Olson EN, Brown JH, Neef S, Maier SK, Maier LS.

Circ Heart Fail. 2009 Nov;2(6):664-75. doi: 10.1161/CIRCHEARTFAILURE.109.865279. Epub 2009 Jul 31.

PMID:
19919992
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

AT1 receptor antagonist restores cardiac ryanodine receptor function, rendering isoproterenol-induced failing heart less susceptible to Ca2+ -leak induced by oxidative stress.

Tokuhisa T, Yano M, Obayashi M, Noma T, Mochizuki M, Oda T, Okuda S, Doi M, Liu J, Ikeda Y, Yamamoto T, Ohkusa T, Matsuzaki M.

Circ J. 2006 Jun;70(6):777-86.

PMID:
16723803
[PubMed - indexed for MEDLINE]
Free Article
20.

Ca²+-dependent phosphorylation of RyR2 can uncouple channel gating from direct cytosolic Ca²+ regulation.

Carter S, Pitt SJ, Colyer J, Sitsapesan R.

J Membr Biol. 2011 Mar;240(1):21-33. doi: 10.1007/s00232-011-9339-9. Epub 2011 Jan 28.

PMID:
21274522
[PubMed - indexed for MEDLINE]
Free PMC Article
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