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Results: 1 to 20 of 104

1.

Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of mammalian sex determination.

Munger SC, Natarajan A, Looger LL, Ohler U, Capel B.

PLoS Genet. 2013;9(7):e1003630. doi: 10.1371/journal.pgen.1003630. Epub 2013 Jul 11.

PMID:
23874228
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.

Munger SC, Aylor DL, Syed HA, Magwene PM, Threadgill DW, Capel B.

Genes Dev. 2009 Nov 1;23(21):2521-36. doi: 10.1101/gad.1835809.

PMID:
19884258
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway.

Correa SM, Washburn LL, Kahlon RS, Musson MC, Bouma GJ, Eicher EM, Albrecht KH.

PLoS Genet. 2012;8(4):e1002569. doi: 10.1371/journal.pgen.1002569. Epub 2012 Apr 5.

PMID:
22496664
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal.

Maatouk DM, DiNapoli L, Alvers A, Parker KL, Taketo MM, Capel B.

Hum Mol Genet. 2008 Oct 1;17(19):2949-55. doi: 10.1093/hmg/ddn193. Epub 2008 Jul 9.

PMID:
18617533
[PubMed - indexed for MEDLINE]
Free PMC Article
5.
6.

Sex and the circuitry: progress toward a systems-level understanding of vertebrate sex determination.

Munger SC, Capel B.

Wiley Interdiscip Rev Syst Biol Med. 2012 Jul-Aug;4(4):401-12. doi: 10.1002/wsbm.1172. Epub 2012 May 17.

PMID:
22605638
[PubMed - indexed for MEDLINE]
7.

Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice.

Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S.

PLoS Genet. 2013;9(1):e1003160. doi: 10.1371/journal.pgen.1003160. Epub 2013 Jan 3.

PMID:
23300479
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Different levels of testicular organization during gonadal differentiation in B6.Y(Tir) mice manifesting sex reversal.

Antonio-Rubio NR, Moreno-Mendoza N.

Cell Biol Int. 2012 Sep;36(9):811-22. doi: 10.1042/CBI20110653.

PMID:
22582735
[PubMed - indexed for MEDLINE]
9.

A microRNA (mmu-miR-124) prevents Sox9 expression in developing mouse ovarian cells.

Real FM, Sekido R, Lupiáñez DG, Lovell-Badge R, Jiménez R, Burgos M.

Biol Reprod. 2013 Oct 4;89(4):78. doi: 10.1095/biolreprod.113.110957. Print 2013 Oct.

PMID:
23946534
[PubMed - indexed for MEDLINE]
Free Article
10.

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.

Sekido R, Lovell-Badge R.

Nature. 2008 Jun 12;453(7197):930-4. doi: 10.1038/nature06944. Epub 2008 May 4. Erratum in: Nature. 2008 Dec 11;456(7223):824.

PMID:
18454134
[PubMed - indexed for MEDLINE]
11.

New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation.

Bouma GJ, Hudson QJ, Washburn LL, Eicher EM.

Biol Reprod. 2010 Feb;82(2):380-9. doi: 10.1095/biolreprod.109.079822. Epub 2009 Oct 28.

PMID:
19864314
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

XY Sox9 embryonic loss-of-function mouse mutants show complete sex reversal and produce partially fertile XY oocytes.

Lavery R, Lardenois A, Ranc-Jianmotamedi F, Pauper E, Gregoire EP, Vigier C, Moreilhon C, Primig M, Chaboissier MC.

Dev Biol. 2011 Jun 1;354(1):111-22. doi: 10.1016/j.ydbio.2011.03.029. Epub 2011 Apr 3.

PMID:
21466799
[PubMed - indexed for MEDLINE]
Free Article
13.

Analysis of gene function in cultured embryonic mouse gonads using nucleofection.

Ryan J, Ludbrook L, Wilhelm D, Sinclair A, Koopman P, Bernard P, Harley VR.

Sex Dev. 2011;5(1):7-15. doi: 10.1159/000322162. Epub 2010 Nov 22.

PMID:
21099207
[PubMed - indexed for MEDLINE]
14.

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination.

Kim Y, Kobayashi A, Sekido R, DiNapoli L, Brennan J, Chaboissier MC, Poulat F, Behringer RR, Lovell-Badge R, Capel B.

PLoS Biol. 2006 Jun;4(6):e187. Epub 2006 May 23.

PMID:
16700629
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Wnt signaling in ovarian development inhibits Sf1 activation of Sox9 via the Tesco enhancer.

Bernard P, Ryan J, Sim H, Czech DP, Sinclair AH, Koopman P, Harley VR.

Endocrinology. 2012 Feb;153(2):901-12. doi: 10.1210/en.2011-1347. Epub 2011 Nov 29.

PMID:
22128028
[PubMed - indexed for MEDLINE]
16.

Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals.

Lavery R, Chassot AA, Pauper E, Gregoire EP, Klopfenstein M, de Rooij DG, Mark M, Schedl A, Ghyselinck NB, Chaboissier MC.

PLoS Genet. 2012;8(12):e1003170. doi: 10.1371/journal.pgen.1003170. Epub 2012 Dec 27.

PMID:
23300469
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Effects of tamoxifen on the sex determination gene and the activation of sex reversal in the developing gonad of mice.

Yu M, Wang J, Liu W, Qin J, Zhou Q, Wang Y, Huang H, Chen W, Ma C.

Toxicology. 2014 Jul 3;321:89-95. doi: 10.1016/j.tox.2014.04.006. Epub 2014 Apr 24.

PMID:
24769059
[PubMed - indexed for MEDLINE]
18.

Homeoproteins Six1 and Six4 regulate male sex determination and mouse gonadal development.

Fujimoto Y, Tanaka SS, Yamaguchi YL, Kobayashi H, Kuroki S, Tachibana M, Shinomura M, Kanai Y, Morohashi K, Kawakami K, Nishinakamura R.

Dev Cell. 2013 Aug 26;26(4):416-30. doi: 10.1016/j.devcel.2013.06.018.

PMID:
23987514
[PubMed - indexed for MEDLINE]
19.

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.

Bogani D, Siggers P, Brixey R, Warr N, Beddow S, Edwards J, Williams D, Wilhelm D, Koopman P, Flavell RA, Chi H, Ostrer H, Wells S, Cheeseman M, Greenfield A.

PLoS Biol. 2009 Sep;7(9):e1000196. doi: 10.1371/journal.pbio.1000196. Epub 2009 Sep 15.

PMID:
19753101
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The transcription co-factor CITED2 functions during sex determination and early gonad development.

Buaas FW, Val P, Swain A.

Hum Mol Genet. 2009 Aug 15;18(16):2989-3001. doi: 10.1093/hmg/ddp237. Epub 2009 May 20.

PMID:
19457926
[PubMed - indexed for MEDLINE]
Free Article

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