Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 119

1.

Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.

Fregoso OI, Ahn J, Wang C, Mehrens J, Skowronski J, Emerman M.

PLoS Pathog. 2013;9(7):e1003496. doi: 10.1371/journal.ppat.1003496. Epub 2013 Jul 18.

PMID:
23874202
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.

Lim ES, Fregoso OI, McCoy CO, Matsen FA, Malik HS, Emerman M.

Cell Host Microbe. 2012 Feb 16;11(2):194-204. doi: 10.1016/j.chom.2012.01.004. Epub 2012 Jan 26.

PMID:
22284954
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation.

DeLucia M, Mehrens J, Wu Y, Ahn J.

J Biol Chem. 2013 Jun 28;288(26):19116-26. doi: 10.1074/jbc.M113.469007. Epub 2013 May 15.

PMID:
23677995
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Variation of two primate lineage-specific residues in human SAMHD1 confers resistance to N terminus-targeted SIV Vpx proteins.

Wei W, Guo H, Gao Q, Markham R, Yu XF.

J Virol. 2014 Jan;88(1):583-91. doi: 10.1128/JVI.02866-13. Epub 2013 Oct 30.

PMID:
24173216
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Structural basis of lentiviral subversion of a cellular protein degradation pathway.

Schwefel D, Groom HC, Boucherit VC, Christodoulou E, Walker PA, Stoye JP, Bishop KN, Taylor IA.

Nature. 2014 Jan 9;505(7482):234-8. doi: 10.1038/nature12815. Epub 2013 Dec 15.

PMID:
24336198
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A novel DCAF1-binding motif required for Vpx-mediated degradation of nuclear SAMHD1 and Vpr-induced G2 arrest.

Wei W, Guo H, Han X, Liu X, Zhou X, Zhang W, Yu XF.

Cell Microbiol. 2012 Nov;14(11):1745-56. doi: 10.1111/j.1462-5822.2012.01835.x. Epub 2012 Aug 9.

PMID:
22776683
[PubMed - indexed for MEDLINE]
7.

HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.

Ahn J, Hao C, Yan J, DeLucia M, Mehrens J, Wang C, Gronenborn AM, Skowronski J.

J Biol Chem. 2012 Apr 6;287(15):12550-8. doi: 10.1074/jbc.M112.340711. Epub 2012 Feb 23.

PMID:
22362772
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein.

Laguette N, Rahm N, Sobhian B, Chable-Bessia C, Münch J, Snoeck J, Sauter D, Switzer WM, Heneine W, Kirchhoff F, Delsuc F, Telenti A, Benkirane M.

Cell Host Microbe. 2012 Feb 16;11(2):205-17. doi: 10.1016/j.chom.2012.01.007. Epub 2012 Feb 1.

PMID:
22305291
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complex.

Sharifi HJ, Furuya AK, Jellinger RM, Nekorchuk MD, de Noronha CM.

J Virol. 2014 Jun;88(12):6944-58. doi: 10.1128/JVI.00241-14. Epub 2014 Apr 9.

PMID:
24719410
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Lentivirus Vpr and Vpx accessory proteins usurp the cullin4-DDB1 (DCAF1) E3 ubiquitin ligase.

Romani B, Cohen EA.

Curr Opin Virol. 2012 Dec;2(6):755-63. doi: 10.1016/j.coviro.2012.09.010. Epub 2012 Oct 10. Review.

PMID:
23062609
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac.

Brandariz-Nuñez A, Valle-Casuso JC, White TE, Laguette N, Benkirane M, Brojatsch J, Diaz-Griffero F.

Retrovirology. 2012 Jun 12;9:49. doi: 10.1186/1742-4690-9-49.

PMID:
22691373
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Co-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestor.

Zhang C, de Silva S, Wang JH, Wu L.

PLoS One. 2012;7(5):e37477. doi: 10.1371/journal.pone.0037477. Epub 2012 May 4.

PMID:
22574228
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Antagonism of SAMHD1 is actively maintained in natural infections of simian immunodeficiency virus.

Spragg CJ, Emerman M.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21136-41. doi: 10.1073/pnas.1316839110. Epub 2013 Dec 9.

PMID:
24324150
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Cell cycle inhibitory effects of HIV and SIV Vpr and Vpx in the yeast Schizosaccharomyces pombe.

Zhang C, Rasmussen C, Chang LJ.

Virology. 1997 Mar 31;230(1):103-12.

PMID:
9126266
[PubMed - indexed for MEDLINE]
Free Article
15.

Transactivation is a conserved function among primate lentivirus Vpr proteins but is not shared by Vpx.

Philippon V, Matsuda Z, Essex M.

J Hum Virol. 1999 May-Jun;2(3):167-74.

PMID:
10413368
[PubMed - indexed for MEDLINE]
16.

Differential apoptosis effects of primate lentiviral Vpr and Vpx in mammalian cells.

Chang LJ, Chen CH, Urlacher V, Lee TZ.

J Biomed Sci. 2000 Jul-Aug;7(4):322-33.

PMID:
10895056
[PubMed - indexed for MEDLINE]
17.

Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration.

Reinhard C, Bottinelli D, Kim B, Luban J.

Retrovirology. 2014 Feb 1;11:12. doi: 10.1186/1742-4690-11-12.

PMID:
24485168
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Functional analysis of the relationship between Vpx and the restriction factor SAMHD1.

Berger G, Turpin J, Cordeil S, Tartour K, Nguyen XN, Mahieux R, Cimarelli A.

J Biol Chem. 2012 Nov 30;287(49):41210-7. doi: 10.1074/jbc.M112.403816. Epub 2012 Oct 17.

PMID:
23076149
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Evolution of the primate lentiviruses: evidence from vpx and vpr.

Tristem M, Marshall C, Karpas A, Hill F.

EMBO J. 1992 Sep;11(9):3405-12.

PMID:
1324171
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Identification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradation.

Guo H, Wei W, Wei Z, Liu X, Evans SL, Yang W, Wang H, Guo Y, Zhao K, Zhou JY, Yu XF.

PLoS One. 2013 Jul 11;8(7):e66201. doi: 10.1371/journal.pone.0066201. Print 2013.

PMID:
23874389
[PubMed - indexed for MEDLINE]
Free PMC Article
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk