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Defective dendritic cell response to Toll-like receptor 7/8 agonists in perinatally HIV-infected children.

Selvaraj A, Pilakka-Kanthikeel S, Bhavani PK, Hanna LE, Pahwa S, Swaminathan S.

Pathog Dis. 2013 Dec;69(3):184-93. doi: 10.1111/2049-632X.12067. Epub 2013 Aug 19.


Impaired CCR7 expression on plasmacytoid dendritic cells of HIV-infected children and adolescents with immunologic and virologic failure.

Desai S, Chaparro A, Liu H, Haslett P, Arheart K, Scott G, Pahwa R, Pahwa S.

J Acquir Immune Defic Syndr. 2007 Aug 15;45(5):501-7.


Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands.

Martinson JA, Roman-Gonzalez A, Tenorio AR, Montoya CJ, Gichinga CN, Rugeles MT, Tomai M, Krieg AM, Ghanekar S, Baum LL, Landay AL.

Cell Immunol. 2007 Nov-Dec;250(1-2):75-84. doi: 10.1016/j.cellimm.2008.01.007. Epub 2008 Mar 10.


Differential regulation of toll-like receptor pathways in acute and chronic HIV-1 infection.

Chang JJ, Lacas A, Lindsay RJ, Doyle EH, Axten KL, Pereyra F, Rosenberg ES, Walker BD, Allen TM, Altfeld M.

AIDS. 2012 Mar 13;26(5):533-41. doi: 10.1097/QAD.0b013e32834f3167.


Differential restoration of myeloid and plasmacytoid dendritic cells in HIV-1-infected children after treatment with highly active antiretroviral therapy.

Zhang Z, Fu J, Zhao Q, He Y, Jin L, Zhang H, Yao J, Zhang L, Wang FS.

J Immunol. 2006 May 1;176(9):5644-51.


Robust interferon-α and IL-12 responses by dendritic cells are related to efficient CD4+ T-cell recovery in HIV patients on ART.

Tan DB, Yong YK, Lim A, Tan HY, Kamarulzaman A, French M, Price P.

Clin Immunol. 2011 May;139(2):115-21. doi: 10.1016/j.clim.2011.02.015. Epub 2011 Feb 23.


Dendritic and natural killer cell subsets associated with stable or declining CD4+ cell counts in treated HIV-1-infected children.

Azzoni L, Rutstein RM, Chehimi J, Farabaugh MA, Nowmos A, Montaner LJ.

J Infect Dis. 2005 May 1;191(9):1451-9. Epub 2005 Mar 30.


Plasmacytoid dendritic cell number and responses to Toll-like receptor 7 and 9 agonists vary in HIV Type 1-infected individuals in relation to clinical state.

Kaushik S, Teque F, Patel M, Fujimura SH, Schmidt B, Levy JA.

AIDS Res Hum Retroviruses. 2013 Mar;29(3):501-10. doi: 10.1089/AID.2012.0200. Epub 2013 Jan 15.


Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals.

Chehimi J, Campbell DE, Azzoni L, Bacheller D, Papasavvas E, Jerandi G, Mounzer K, Kostman J, Trinchieri G, Montaner LJ.

J Immunol. 2002 May 1;168(9):4796-801.


Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod.

Gibson SJ, Lindh JM, Riter TR, Gleason RM, Rogers LM, Fuller AE, Oesterich JL, Gorden KB, Qiu X, McKane SW, Noelle RJ, Miller RL, Kedl RM, Fitzgerald-Bocarsly P, Tomai MA, Vasilakos JP.

Cell Immunol. 2002 Jul-Aug;218(1-2):74-86.


The TLR7/8 ligand resiquimod targets monocyte-derived dendritic cell differentiation via TLR8 and augments functional dendritic cell generation.

Hackstein H, Knoche A, Nockher A, Poeling J, Kubin T, Jurk M, Vollmer J, Bein G.

Cell Immunol. 2011;271(2):401-12. doi: 10.1016/j.cellimm.2011.08.008. Epub 2011 Aug 22.


Dysregulated immunophenotypic attributes of plasmacytoid but not myeloid dendritic cells in HIV-1 infected individuals in the absence of highly active anti-retroviral therapy.

Benlahrech A, Yasmin A, Westrop SJ, Coleman A, Herasimtschuk A, Page E, Kelleher P, Gotch F, Imami N, Patterson S.

Clin Exp Immunol. 2012 Nov;170(2):212-21. doi: 10.1111/j.1365-2249.2012.04647.x.


Evidence of dysregulation of dendritic cells in primary HIV infection.

Sabado RL, O'Brien M, Subedi A, Qin L, Hu N, Taylor E, Dibben O, Stacey A, Fellay J, Shianna KV, Siegal F, Shodell M, Shah K, Larsson M, Lifson J, Nadas A, Marmor M, Hutt R, Margolis D, Garmon D, Markowitz M, Valentine F, Borrow P, Bhardwaj N.

Blood. 2010 Nov 11;116(19):3839-52. doi: 10.1182/blood-2010-03-273763. Epub 2010 Aug 6.


Differential effects of P-class versus other CpG oligodeoxynucleotide classes on the impaired innate immunity of plasmacytoid dendritic cells in HIV type 1 infection.

Donhauser N, Helm M, Pritschet K, Schuster P, Ries M, Korn K, Vollmer J, Schmidt B.

AIDS Res Hum Retroviruses. 2010 Feb;26(2):161-71. doi: 10.1089/aid.2008.0278.


Immunologic function and virologic suppression among children with perinatally acquired HIV Infection on highly active antiretroviral therapy.

Rutstein RM, Gebo KA, Flynn PM, Fleishman JA, Sharp VL, Siberry GK, Spector SA.

Med Care. 2005 Sep;43(9 Suppl):III15-22.


Plasmacytoid dendritic cell interferon-α production to R-848 stimulation is decreased in male infants.

Wang JP, Zhang L, Madera RF, Woda M, Libraty DH.

BMC Immunol. 2012 Jul 6;13:35. doi: 10.1186/1471-2172-13-35.


Plasmacytoid dendritic cells count in antiretroviral-treated patients is predictive of HIV load control independent of CD4+ T-cell count.

Lichtner M, Rossi R, Rizza MC, Mengoni F, Sauzullo I, Massetti AP, Luzi G, Hosmalin A, Mastroianni CM, Vullo V.

Curr HIV Res. 2008 Jan;6(1):19-27.


Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion.

Badolato R, Ghidini C, Facchetti F, Serana F, Sottini A, Chiarini M, Spinelli E, Lonardi S, Plebani A, Caimi L, Imberti L.

J Transl Med. 2008 Sep 9;6:49. doi: 10.1186/1479-5876-6-49.

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