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Results: 1 to 20 of 101

1.

A post-synthetic approach for the synthesis of 2'-O-methyldithiomethyl-modified oligonucleotides responsive to a reducing environment.

Ochi Y, Nakagawa O, Sakaguchi K, Wada S, Urata H.

Chem Commun (Camb). 2013 Sep 7;49(69):7620-2. doi: 10.1039/c3cc43725f. Epub 2013 Jul 19.

PMID:
23872984
[PubMed - indexed for MEDLINE]
2.

Synthesis and hybridization property of sugar and phosphate linkage modified oligonucleotides.

Jeong LS, Lee JH, Jung KE, Moon HR, Kim K, Lim H.

Bioorg Med Chem. 1999 Jul;7(7):1467-73.

PMID:
10465421
[PubMed - indexed for MEDLINE]
3.

Stabilization of double-stranded oligonucleotides using backbone-linked disulfide bridges.

Gao H, Yang M, Cook AF.

Nucleic Acids Res. 1995 Jan 25;23(2):285-92.

PMID:
7862534
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Intramolecular free-radical cyclization reactions on pentose sugars for the synthesis of carba-LNA and carba-ENA and the application of their modified oligonucleotides as potential RNA targeted therapeutics.

Zhou C, Chattopadhyaya J.

Chem Rev. 2012 Jul 11;112(7):3808-32. doi: 10.1021/cr100306q. Epub 2012 Apr 24. Review. No abstract available.

PMID:
22530946
[PubMed - indexed for MEDLINE]
5.

Automated solid-phase synthesis of RNA oligonucleotides containing a nonbridging phosphorodithioate linkage via phosphorothioamidites.

Li NS, Frederiksen JK, Piccirilli JA.

J Org Chem. 2012 Nov 2;77(21):9889-92. doi: 10.1021/jo301834p. Epub 2012 Oct 25.

PMID:
23050987
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Rapid routes of synthesis of chemically reactive and highly radioactively labeled alpha- and beta-oligonucleotide derivatives for in vivo studies.

Boutorine AS, Le Doan T, Battioni JP, Mansuy D, Dupré D, Hélène C.

Bioconjug Chem. 1990 Sep-Oct;1(5):350-6.

PMID:
1965883
[PubMed - indexed for MEDLINE]
7.

Synthesis of 2'-O-[2-[(N,N-dimethylamino)oxy]ethyl] modified nucleosides and oligonucleotides.

Prakash TP, Kawasaki AM, Fraser AS, Vasquez G, Manoharan M.

J Org Chem. 2002 Jan 25;67(2):357-69.

PMID:
11798305
[PubMed - indexed for MEDLINE]
8.

Approach to the synthesis of natural and modified oligonucleotides by the phosphotriester method using O-nucleophilic intramolecular catalysis.

Efimov VA, Molchanova NS, Chakhmakhcheva OG.

Nucleosides Nucleotides Nucleic Acids. 2007;26(8-9):1087-93.

PMID:
18058542
[PubMed - indexed for MEDLINE]
9.

Chimeric RNA with modified backbones: alternating methylene(methylimino) linked phosphodiester backbone oligonucleotides with 2'-OH and 2'-OMe groups.

Prhavc M, Bhat B, Just G, Cook PD, Manoharan M.

Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):995-7.

PMID:
11563162
[PubMed - indexed for MEDLINE]
10.

One-electron reductive template-directed ligation of oligodeoxynucleotides possessing a disulfide bond.

Tanabe K, Kuraseko E, Yamamoto Y, Nishimoto S.

J Am Chem Soc. 2008 May 21;130(20):6302-3. doi: 10.1021/ja7111614. Epub 2008 Apr 29.

PMID:
18444625
[PubMed - indexed for MEDLINE]
11.

Synthesis and properties of 2'-O,4'-C-ethyleneoxy bridged 5-methyluridine.

Hari Y, Morikawa T, Osawa T, Obika S.

Org Lett. 2013 Jul 19;15(14):3702-5. doi: 10.1021/ol401566r. Epub 2013 Jul 1.

PMID:
23815244
[PubMed - indexed for MEDLINE]
12.

2'-O-[2-(guanidinium)ethyl]-modified oligonucleotides: stabilizing effect on duplex and triplex structures.

Prakash TP, Püschl A, Lesnik E, Mohan V, Tereshko V, Egli M, Manoharan M.

Org Lett. 2004 Jun 10;6(12):1971-4.

PMID:
15176796
[PubMed - indexed for MEDLINE]
13.

Phosphorylating reagent-free synthesis of 5'-phosphate oligonucleotides by controlled oxidative degradation of their 5'-end.

Sallamand C, Miscioscia A, Lartia R, Defrancq E.

Org Lett. 2012 Apr 20;14(8):2030-3. doi: 10.1021/ol300542s. Epub 2012 Apr 5.

PMID:
22480332
[PubMed - indexed for MEDLINE]
14.

Solid phase synthesis of phosphorothioate oligonucleotides utilizing diethyldithiocarbonate disulfide (DDD) as an efficient sulfur transfer reagent.

Cheruvallath ZS, Kumar RK, Rentel C, Cole DL, Ravikumar VT.

Nucleosides Nucleotides Nucleic Acids. 2003 Apr;22(4):461-8.

PMID:
12885126
[PubMed - indexed for MEDLINE]
15.
16.

An improved method for the synthesis and deprotection of methylphosphonate oligonucleotides.

Hogrefe RI, Reynolds MA, Vaghefi MM, Young KM, Riley TA, Klem RE, Arnold LJ Jr.

Methods Mol Biol. 1993;20:143-64.

PMID:
8242134
[PubMed - indexed for MEDLINE]
17.

Oligonucleotide N3'-->P5' phosphoramidates.

Gryaznov SM, Lloyd DH, Chen JK, Schultz RG, DeDionisio LA, Ratmeyer L, Wilson WD.

Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5798-802.

PMID:
7541136
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Photochemical generation of ribose abasic sites in RNA oligonucleotides.

Trzupek JD, Sheppard TL.

Org Lett. 2005 Apr 14;7(8):1493-6.

PMID:
15816735
[PubMed - indexed for MEDLINE]
19.

Synthetic oligonucleotides as RNA mimetics: 2'-modified Rnas and N3'-->P5' phosphoramidates.

Egli M, Gryaznov SM.

Cell Mol Life Sci. 2000 Sep;57(10):1440-56. Review.

PMID:
11078022
[PubMed - indexed for MEDLINE]
20.

End-labeling oligonucleotides with chemical tags after synthesis.

Zearfoss NR, Ryder SP.

Methods Mol Biol. 2012;941:181-93. doi: 10.1007/978-1-62703-113-4_14.

PMID:
23065562
[PubMed - indexed for MEDLINE]

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