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Results: 1 to 20 of 101

1.

Effect of C-terminal sequence on competitive semaphorin binding to neuropilin-1.

Parker MW, Linkugel AD, Vander Kooi CW.

J Mol Biol. 2013 Nov 15;425(22):4405-14. doi: 10.1016/j.jmb.2013.07.017. Epub 2013 Jul 17.

PMID:
23871893
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mechanistic basis for the potent anti-angiogenic activity of semaphorin 3F.

Guo HF, Li X, Parker MW, Waltenberger J, Becker PM, Vander Kooi CW.

Biochemistry. 2013 Oct 29;52(43):7551-8. doi: 10.1021/bi401034q. Epub 2013 Oct 18.

PMID:
24079887
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mechanism of selective VEGF-A binding by neuropilin-1 reveals a basis for specific ligand inhibition.

Parker MW, Xu P, Guo HF, Vander Kooi CW.

PLoS One. 2012;7(11):e49177. doi: 10.1371/journal.pone.0049177. Epub 2012 Nov 8.

PMID:
23145112
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin.

Parker MW, Hellman LM, Xu P, Fried MG, Vander Kooi CW.

Biochemistry. 2010 May 18;49(19):4068-75. doi: 10.1021/bi100327r.

PMID:
20387901
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Structural basis for ligand and heparin binding to neuropilin B domains.

Vander Kooi CW, Jusino MA, Perman B, Neau DB, Bellamy HD, Leahy DJ.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6152-7. Epub 2007 Apr 3.

PMID:
17405859
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding.

Appleton BA, Wu P, Maloney J, Yin J, Liang WC, Stawicki S, Mortara K, Bowman KK, Elliott JM, Desmarais W, Bazan JF, Bagri A, Tessier-Lavigne M, Koch AW, Wu Y, Watts RJ, Wiesmann C.

EMBO J. 2007 Nov 28;26(23):4902-12. Epub 2007 Nov 8.

PMID:
17989695
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Structure-function analysis of the antiangiogenic ATWLPPR peptide inhibiting VEGF(165) binding to neuropilin-1 and molecular dynamics simulations of the ATWLPPR/neuropilin-1 complex.

Starzec A, Ladam P, Vassy R, Badache S, Bouchemal N, Navaza A, du Penhoat CH, Perret GY.

Peptides. 2007 Dec;28(12):2397-402. Epub 2007 Sep 29.

PMID:
17983687
[PubMed - indexed for MEDLINE]
8.

Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis.

Geretti E, Shimizu A, Klagsbrun M.

Angiogenesis. 2008;11(1):31-9. doi: 10.1007/s10456-008-9097-1. Epub 2008 Feb 19. Review.

PMID:
18283547
[PubMed - indexed for MEDLINE]
9.

Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis.

Gaur P, Bielenberg DR, Samuel S, Bose D, Zhou Y, Gray MJ, Dallas NA, Fan F, Xia L, Lu J, Ellis LM.

Clin Cancer Res. 2009 Nov 15;15(22):6763-70. doi: 10.1158/1078-0432.CCR-09-1810. Epub 2009 Nov 3. Review.

PMID:
19887479
[PubMed - indexed for MEDLINE]
Free Article
10.

Structural and functional relation of neuropilins.

Nakamura F, Goshima Y.

Adv Exp Med Biol. 2002;515:55-69. Review.

PMID:
12613543
[PubMed - indexed for MEDLINE]
11.

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration.

Teesalu T, Sugahara KN, Kotamraju VR, Ruoslahti E.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16157-62. doi: 10.1073/pnas.0908201106. Epub 2009 Sep 2.

PMID:
19805273
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.

Janssen BJ, Malinauskas T, Weir GA, Cader MZ, Siebold C, Jones EY.

Nat Struct Mol Biol. 2012 Dec;19(12):1293-9. doi: 10.1038/nsmb.2416. Epub 2012 Oct 28.

PMID:
23104057
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Targeting endothelial and tumor cells with semaphorins.

Bielenberg DR, Klagsbrun M.

Cancer Metastasis Rev. 2007 Dec;26(3-4):421-31. Review.

PMID:
17768598
[PubMed - indexed for MEDLINE]
14.

Sugar-based peptidomimetics as potential inhibitors of the vascular endothelium growth factor binding to neuropilin-1.

Novoa A, Pellegrini-Moïse N, Bechet D, Barberi-Heyob M, Chapleur Y.

Bioorg Med Chem. 2010 May 1;18(9):3285-98. doi: 10.1016/j.bmc.2010.03.012. Epub 2010 Mar 12.

PMID:
20363638
[PubMed - indexed for MEDLINE]
15.

Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1.

Parker MW, Xu P, Li X, Vander Kooi CW.

J Biol Chem. 2012 Mar 30;287(14):11082-9. doi: 10.1074/jbc.M111.331140. Epub 2012 Feb 7.

PMID:
22318724
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR.

Cébe-Suarez S, Grünewald FS, Jaussi R, Li X, Claesson-Welsh L, Spillmann D, Mercer AA, Prota AE, Ballmer-Hofer K.

FASEB J. 2008 Aug;22(8):3078-86. doi: 10.1096/fj.08-107219. Epub 2008 May 8.

PMID:
18467594
[PubMed - indexed for MEDLINE]
Free Article
17.

Function of members of the neuropilin family as essential pleiotropic cell surface receptors.

Parker MW, Guo HF, Li X, Linkugel AD, Vander Kooi CW.

Biochemistry. 2012 Nov 27;51(47):9437-46. doi: 10.1021/bi3012143. Epub 2012 Nov 14. Review.

PMID:
23116416
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Site-directed mutagenesis in the B-neuropilin-2 domain selectively enhances its affinity to VEGF165, but not to semaphorin 3F.

Geretti E, Shimizu A, Kurschat P, Klagsbrun M.

J Biol Chem. 2007 Aug 31;282(35):25698-707. Epub 2007 Jun 26.

PMID:
17595163
[PubMed - indexed for MEDLINE]
Free Article
19.

Relative effects of VEGF-A and VEGF-C on endothelial cell proliferation, migration and PAF synthesis: Role of neuropilin-1.

Bernatchez PN, Rollin S, Soker S, Sirois MG.

J Cell Biochem. 2002;85(3):629-39.

PMID:
11968003
[PubMed - indexed for MEDLINE]
20.

Binding of a C-end rule peptide to the neuropilin-1 receptor: a molecular modeling approach.

Haspel N, Zanuy D, Nussinov R, Teesalu T, Ruoslahti E, Aleman C.

Biochemistry. 2011 Mar 15;50(10):1755-62. doi: 10.1021/bi101662j. Epub 2011 Feb 14.

PMID:
21247217
[PubMed - indexed for MEDLINE]
Free PMC Article

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