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Results: 1 to 20 of 105

1.

Assembly-directed antivirals differentially bind quasiequivalent pockets to modify hepatitis B virus capsid tertiary and quaternary structure.

Katen SP, Tan Z, Chirapu SR, Finn MG, Zlotnick A.

Structure. 2013 Aug 6;21(8):1406-16. doi: 10.1016/j.str.2013.06.013. Epub 2013 Jul 18.

PMID:
23871485
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Global structural changes in hepatitis B virus capsids induced by the assembly effector HAP1.

Bourne CR, Finn MG, Zlotnick A.

J Virol. 2006 Nov;80(22):11055-61. Epub 2006 Aug 30.

PMID:
16943288
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Phase diagrams map the properties of antiviral agents directed against hepatitis B virus core assembly.

Li L, Chirapu SR, Finn MG, Zlotnick A.

Antimicrob Agents Chemother. 2013 Mar;57(3):1505-8. doi: 10.1128/AAC.01766-12. Epub 2012 Dec 3.

PMID:
23208717
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly.

Stray SJ, Bourne CR, Punna S, Lewis WG, Finn MG, Zlotnick A.

Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8138-43. Epub 2005 May 31.

PMID:
15928089
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Trapping of hepatitis B virus capsid assembly intermediates by phenylpropenamide assembly accelerators.

Katen SP, Chirapu SR, Finn MG, Zlotnick A.

ACS Chem Biol. 2010 Dec 17;5(12):1125-36. doi: 10.1021/cb100275b. Epub 2010 Oct 4.

PMID:
20845949
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Small-molecule effectors of hepatitis B virus capsid assembly give insight into virus life cycle.

Bourne C, Lee S, Venkataiah B, Lee A, Korba B, Finn MG, Zlotnick A.

J Virol. 2008 Oct;82(20):10262-70. doi: 10.1128/JVI.01360-08. Epub 2008 Aug 6.

PMID:
18684823
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

An in vitro fluorescence screen to identify antivirals that disrupt hepatitis B virus capsid assembly.

Stray SJ, Johnson JM, Kopek BG, Zlotnick A.

Nat Biotechnol. 2006 Mar;24(3):358-62. Epub 2006 Feb 12.

PMID:
16474383
[PubMed - indexed for MEDLINE]
8.

A mutant hepatitis B virus core protein mimics inhibitors of icosahedral capsid self-assembly.

Bourne CR, Katen SP, Fulz MR, Packianathan C, Zlotnick A.

Biochemistry. 2009 Mar 3;48(8):1736-42. doi: 10.1021/bi801814y.

PMID:
19196007
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Characterization of the mode of action of a potent dengue virus capsid inhibitor.

Scaturro P, Trist IM, Paul D, Kumar A, Acosta EG, Byrd CM, Jordan R, Brancale A, Bartenschlager R.

J Virol. 2014 Oct;88(19):11540-55. doi: 10.1128/JVI.01745-14. Epub 2014 Jul 23.

PMID:
25056895
[PubMed - indexed for MEDLINE]
10.

BAY 41-4109 has multiple effects on Hepatitis B virus capsid assembly.

Stray SJ, Zlotnick A.

J Mol Recognit. 2006 Nov-Dec;19(6):542-8.

PMID:
17006877
[PubMed - indexed for MEDLINE]
11.

Antigenic switching of hepatitis B virus by alternative dimerization of the capsid protein.

DiMattia MA, Watts NR, Stahl SJ, Grimes JM, Steven AC, Stuart DI, Wingfield PT.

Structure. 2013 Jan 8;21(1):133-42. doi: 10.1016/j.str.2012.10.017. Epub 2012 Dec 6.

PMID:
23219881
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Structure-based design and biochemical evaluation of sulfanilamide derivatives as hepatitis B virus capsid assembly inhibitors.

Cho MH, Song JS, Kim HJ, Park SG, Jung G.

J Enzyme Inhib Med Chem. 2013 Oct;28(5):916-25. doi: 10.3109/14756366.2012.694879. Epub 2012 Jul 18.

PMID:
22803663
[PubMed - indexed for MEDLINE]
13.

Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids.

Campagna MR, Liu F, Mao R, Mills C, Cai D, Guo F, Zhao X, Ye H, Cuconati A, Guo H, Chang J, Xu X, Block TM, Guo JT.

J Virol. 2013 Jun;87(12):6931-42. doi: 10.1128/JVI.00582-13. Epub 2013 Apr 10.

PMID:
23576513
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Weak protein-protein interactions are sufficient to drive assembly of hepatitis B virus capsids.

Ceres P, Zlotnick A.

Biochemistry. 2002 Oct 1;41(39):11525-31.

PMID:
12269796
[PubMed - indexed for MEDLINE]
15.

Interaction between nucleophosmin and HBV core protein increases HBV capsid assembly.

Jeong H, Cho MH, Park SG, Jung G.

FEBS Lett. 2014 Mar 18;588(6):851-8. doi: 10.1016/j.febslet.2014.01.020. Epub 2014 Jan 23.

PMID:
24462683
[PubMed - indexed for MEDLINE]
16.

Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein.

Bartonova V, Igonet S, Sticht J, Glass B, Habermann A, Vaney MC, Sehr P, Lewis J, Rey FA, KraĆ¼sslich HG.

J Biol Chem. 2008 Nov 14;283(46):32024-33. doi: 10.1074/jbc.M804230200. Epub 2008 Sep 4.

PMID:
18772135
[PubMed - indexed for MEDLINE]
Free Article
17.

A small molecule inhibits and misdirects assembly of hepatitis B virus capsids.

Zlotnick A, Ceres P, Singh S, Johnson JM.

J Virol. 2002 May;76(10):4848-54.

PMID:
11967301
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Virus assembly, allostery and antivirals.

Zlotnick A, Mukhopadhyay S.

Trends Microbiol. 2011 Jan;19(1):14-23. doi: 10.1016/j.tim.2010.11.003. Epub 2010 Dec 14. Review.

PMID:
21163649
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Subunit folds and maturation pathway of a dsRNA virus capsid.

Nemecek D, Boura E, Wu W, Cheng N, Plevka P, Qiao J, Mindich L, Heymann JB, Hurley JH, Steven AC.

Structure. 2013 Aug 6;21(8):1374-83. doi: 10.1016/j.str.2013.06.007. Epub 2013 Jul 25.

PMID:
23891288
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Crystal structure of human adenovirus at 3.5 A resolution.

Reddy VS, Natchiar SK, Stewart PL, Nemerow GR.

Science. 2010 Aug 27;329(5995):1071-5. doi: 10.1126/science.1187292.

PMID:
20798318
[PubMed - indexed for MEDLINE]
Free PMC Article

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