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Results: 1 to 20 of 71

1.

Colon cancer progression is driven by APEX1-mediated upregulation of Jagged.

Kim MH, Kim HB, Yoon SP, Lim SC, Cha MJ, Jeon YJ, Park SG, Chang IY, You HJ.

J Clin Invest. 2013 Jul 1. pii: 65521. doi: 10.1172/JCI65521. [Epub ahead of print]

PMID:
23863623
[PubMed - as supplied by publisher]
Free PMC Article
2.

Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer.

Dai Y, Wilson G, Huang B, Peng M, Teng G, Zhang D, Zhang R, Ebert MP, Chen J, Wong BC, Chan KW, George J, Qiao L.

Cell Death Dis. 2014 Apr 10;5:e1170. doi: 10.1038/cddis.2014.137.

PMID:
24722295
[PubMed - in process]
3.

Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation.

Veeraraghavalu K, Pett M, Kumar RV, Nair P, Rangarajan A, Stanley MA, Krishna S.

J Virol. 2004 Aug;78(16):8687-700.

PMID:
15280477
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Elevated Jagged-1 and Notch-1 expression in high grade and metastatic prostate cancers.

Zhu H, Zhou X, Redfield S, Lewin J, Miele L.

Am J Transl Res. 2013 Apr 19;5(3):368-78. Print 2013.

PMID:
23634247
[PubMed]
Free PMC Article
5.

APEX1 gene amplification and its protein overexpression in osteosarcoma: correlation with recurrence, metastasis, and survival.

Yang J, Yang D, Cogdell D, Du X, Li H, Pang Y, Sun Y, Hu L, Sun B, Trent J, Chen K, Zhang W.

Technol Cancer Res Treat. 2010 Apr;9(2):161-9.

PMID:
20218738
[PubMed - indexed for MEDLINE]
6.

HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells.

Belton A, Gabrovsky A, Bae YK, Reeves R, Iacobuzio-Donahue C, Huso DL, Resar LM.

PLoS One. 2012;7(1):e30034. doi: 10.1371/journal.pone.0030034. Epub 2012 Jan 20.

PMID:
22276142
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappaB signaling pathways.

Wang Z, Li Y, Banerjee S, Kong D, Ahmad A, Nogueira V, Hay N, Sarkar FH.

J Cell Biochem. 2010 Mar 1;109(4):726-36. doi: 10.1002/jcb.22451.

PMID:
20052673
[PubMed - indexed for MEDLINE]
8.

Combination DLL4 with Jagged1-siRNA can enhance inhibition of the proliferation and invasiveness activity of human gastric carcinoma by Notch1/VEGF pathway.

Sun HW, Wu C, Tan HY, Wang QS.

Hepatogastroenterology. 2012 May;59(115):924-9. doi: 10.5754/hge11484.

PMID:
22020917
[PubMed - indexed for MEDLINE]
9.

Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling.

Guilmeau S, Flandez M, Mariadason JM, Augenlicht LH.

Oncogene. 2010 Feb 18;29(7):992-1002. doi: 10.1038/onc.2009.393. Epub 2009 Nov 23.

PMID:
19935714
[PubMed - indexed for MEDLINE]
10.

JAGGED1 expression is associated with prostate cancer metastasis and recurrence.

Santagata S, Demichelis F, Riva A, Varambally S, Hofer MD, Kutok JL, Kim R, Tang J, Montie JE, Chinnaiyan AM, Rubin MA, Aster JC.

Cancer Res. 2004 Oct 1;64(19):6854-7.

PMID:
15466172
[PubMed - indexed for MEDLINE]
Free Article
11.

S-adenosylmethionine regulates apurinic/apyrimidinic endonuclease 1 stability: implication in hepatocarcinogenesis.

Tomasi ML, Iglesias-Ara A, Yang H, Ramani K, Feo F, Pascale MR, Martínez-Chantar ML, Mato JM, Lu SC.

Gastroenterology. 2009 Mar;136(3):1025-36. doi: 10.1053/j.gastro.2008.09.026. Epub 2008 Sep 25.

PMID:
18983843
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The notch ligand JAGGED1 as a target for anti-tumor therapy.

Li D, Masiero M, Banham AH, Harris AL.

Front Oncol. 2014 Sep 25;4:254. doi: 10.3389/fonc.2014.00254. eCollection 2014. Review.

PMID:
25309874
[PubMed]
Free PMC Article
13.

The Notch signaling pathway is related to neurovascular progression of pancreatic cancer.

Büchler P, Gazdhar A, Schubert M, Giese N, Reber HA, Hines OJ, Giese T, Ceyhan GO, Müller M, Büchler MW, Friess H.

Ann Surg. 2005 Dec;242(6):791-800, discussion 800-1.

PMID:
16327489
[PubMed - indexed for MEDLINE]
Free PMC Article
14.
15.

Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/VEGFR-2 expression in breast cancer.

Guo S, Gonzalez-Perez RR.

PLoS One. 2011;6(6):e21467. doi: 10.1371/journal.pone.0021467. Epub 2011 Jun 23.

PMID:
21731759
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.

Fathers KE, Bell ES, Rajadurai CV, Cory S, Zhao H, Mourskaia A, Zuo D, Madore J, Monast A, Mes-Masson AM, Grosset AA, Gaboury L, Hallet M, Siegel P, Park M.

Breast Cancer Res. 2012 May 8;14(3):R74.

PMID:
22569336
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Adrenergic signaling promotes angiogenesis through endothelial cell-tumor cell crosstalk.

Chen H, Liu D, Yang Z, Sun L, Deng Q, Yang S, Qian L, Guo L, Yu M, Hu M, Shi M, Guo N.

Endocr Relat Cancer. 2014 Oct;21(5):783-95. doi: 10.1530/ERC-14-0236.

PMID:
25179535
[PubMed - in process]
18.

Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion.

Chen J, Imanaka N, Chen J, Griffin JD.

Br J Cancer. 2010 Jan 19;102(2):351-60. doi: 10.1038/sj.bjc.6605486. Epub 2009 Dec 15.

PMID:
20010940
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

High-level expression of Notch1 increased the risk of metastasis in T1 stage clear cell renal cell carcinoma.

Ai Q, Ma X, Huang Q, Liu S, Shi T, Zhang C, Zhu M, Zhang Y, Wang B, Ni D, Li H, Zheng T, Zhang X.

PLoS One. 2012;7(4):e35022. doi: 10.1371/journal.pone.0035022. Epub 2012 Apr 10.

PMID:
22506064
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Study of AP endonuclease (APEX1/REF1), a DNA repair enzyme, in gallbladder carcinoma.

Shukla VK, das PC, Dixit R, Bhartiya SK, Basu S, Raman MJ.

Anticancer Res. 2012 Apr;32(4):1489-92.

PMID:
22493391
[PubMed - indexed for MEDLINE]

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