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Items: 1 to 20 of 76

1.

hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression.

Avasarala S, Van Scoyk M, Wang J, Sechler M, Vandervest K, Brzezinski C, Weekes C, Edwards MG, Arcaroli J, Davis RE, Bikkavilli RK, Winn RA.

Biol Open. 2013 May 22;2(7):675-85. doi: 10.1242/bio.20134507. Print 2013 Jul 15.

2.

Heterotrimeric G-protein, Gα16, is a critical downstream effector of non-canonical Wnt signaling and a potent inhibitor of transformed cell growth in non small cell lung cancer.

Avasarala S, Bikkavilli RK, Van Scoyk M, Zhang W, Lapite A, Hostetter L, Byers JT, Heasley LE, Sohn JW, Winn RA.

PLoS One. 2013 Oct 18;8(10):e76895. doi: 10.1371/journal.pone.0076895. eCollection 2013.

3.

Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation.

Winn RA, Marek L, Han SY, Rodriguez K, Rodriguez N, Hammond M, Van Scoyk M, Acosta H, Mirus J, Barry N, Bren-Mattison Y, Van Raay TJ, Nemenoff RA, Heasley LE.

J Biol Chem. 2005 May 20;280(20):19625-34. Epub 2005 Feb 10.

4.

Redundant expression of canonical Wnt ligands in human breast cancer cell lines.

Benhaj K, Akcali KC, Ozturk M.

Oncol Rep. 2006 Mar;15(3):701-7.

PMID:
16465433
5.

Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/β-catenin signaling pathway in human lung cancer.

Yang L, Chen Y, Cui T, Knösel T, Zhang Q, Albring KF, Huber O, Petersen I.

Carcinogenesis. 2012 Oct;33(10):1863-70. doi: 10.1093/carcin/bgs226. Epub 2012 Jul 12.

6.

Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer.

Tennis MA, Vanscoyk MM, Wilson LA, Kelley N, Winn RA.

PLoS One. 2012;7(3):e32921. doi: 10.1371/journal.pone.0032921. Epub 2012 Mar 5.

7.
8.

Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells.

Carmon KS, Loose DS.

Mol Cancer Res. 2008 Jun;6(6):1017-28. doi: 10.1158/1541-7786.MCR-08-0039.

9.

WNT7a induces E-cadherin in lung cancer cells.

Ohira T, Gemmill RM, Ferguson K, Kusy S, Roche J, Brambilla E, Zeng C, Baron A, Bemis L, Erickson P, Wilder E, Rustgi A, Kitajewski J, Gabrielson E, Bremnes R, Franklin W, Drabkin HA.

Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10429-34. Epub 2003 Aug 22.

10.

Cyr61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway.

Tong X, O'Kelly J, Xie D, Mori A, Lemp N, McKenna R, Miller CW, Koeffler HP.

Oncogene. 2004 Jun 17;23(28):4847-55.

PMID:
15077166
11.

gamma-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth.

Winn RA, Bremnes RM, Bemis L, Franklin WA, Miller YE, Cool C, Heasley LE.

Oncogene. 2002 Oct 24;21(49):7497-506.

12.

Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells.

Jiang L, Huang Q, Zhang S, Zhang Q, Chang J, Qiu X, Wang E.

BMC Cancer. 2010 Jun 22;10:318. doi: 10.1186/1471-2407-10-318.

14.

Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer.

Bikkavilli RK, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, Edwards MG, Rathinam MK, Zhou T, Tauler J, Borowicz S, Lussier YA, Parr BA, Cool CD, Winn RA.

Oncogene. 2015 Oct 16;34(42):5317-28. doi: 10.1038/onc.2015.2. Epub 2015 Mar 2. Erratum in: Oncogene. 2015 Oct 16;34(42):5406.

15.

MicroRNAs reduce tumor growth and contribute to enhance cytotoxicity induced by gefitinib in non-small cell lung cancer.

Zhong M, Ma X, Sun C, Chen L.

Chem Biol Interact. 2010 Mar 30;184(3):431-8. doi: 10.1016/j.cbi.2010.01.025. Epub 2010 Jan 25.

PMID:
20097187
16.

Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells.

Teng Y, Wang X, Wang Y, Ma D.

Biochem Biophys Res Commun. 2010 Feb 12;392(3):373-9. doi: 10.1016/j.bbrc.2010.01.028. Epub 2010 Jan 13.

PMID:
20074550
17.

Altered HOX and WNT7A expression in human lung cancer.

Calvo R, West J, Franklin W, Erickson P, Bemis L, Li E, Helfrich B, Bunn P, Roche J, Brambilla E, Rosell R, Gemmill RM, Drabkin HA.

Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12776-81.

18.

Peripheral T-lymphocytes express WNT7A and its restoration in leukemia-derived lymphoblasts inhibits cell proliferation.

Ochoa-Hernández AB, Ramos-Solano M, Meza-Canales ID, García-Castro B, Rosales-Reynoso MA, Rosales-Aviña JA, Barrera-Chairez E, Ortíz-Lazareno PC, Hernández-Flores G, Bravo-Cuellar A, Jave-Suarez LF, Barros-Núñez P, Aguilar-Lemarroy A.

BMC Cancer. 2012 Feb 7;12:60. doi: 10.1186/1471-2407-12-60.

19.

MicroRNA-34b functions as a tumor suppressor and acts as a nodal point in the feedback loop with Met.

Wang LG, Ni Y, Su BH, Mu XR, Shen HC, Du JJ.

Int J Oncol. 2013 Mar;42(3):957-62. doi: 10.3892/ijo.2013.1767. Epub 2013 Jan 10.

PMID:
23314612
20.

Ephrin-A1 inhibits NSCLC tumor growth via induction of Cdx-2 a tumor suppressor gene.

Sukka-Ganesh B, Mohammed KA, Kaye F, Goldberg EP, Nasreen N.

BMC Cancer. 2012 Jul 23;12:309. doi: 10.1186/1471-2407-12-309.

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