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Items: 1 to 20 of 107

1.

In vitro testicular toxicity models: opportunities for advancement via biomedical engineering techniques.

Parks Saldutti L, Beyer BK, Breslin W, Brown TR, Chapin RE, Campion S, Enright B, Faustman E, Foster PM, Hartung T, Kelce W, Kim JH, Loboa EG, Piersma AH, Seyler D, Turner KJ, Yu H, Yu X, Sasaki JC.

ALTEX. 2013;30(3):353-77.

2.

Assuring safety without animal testing: the case for the human testis in vitro.

Chapin RE, Boekelheide K, Cortvrindt R, van Duursen MB, Gant T, Jegou B, Marczylo E, van Pelt AM, Post JN, Roelofs MJ, Schlatt S, Teerds KJ, Toppari J, Piersma AH.

Reprod Toxicol. 2013 Aug;39:63-8. doi: 10.1016/j.reprotox.2013.04.004. Epub 2013 Apr 21.

PMID:
23612449
3.

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.

Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P.

Mutat Res. 2007 Mar 30;628(1):31-55. Epub 2007 Jan 13.

PMID:
17293159
4.

The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research.

Embry MR, Belanger SE, Braunbeck TA, Galay-Burgos M, Halder M, Hinton DE, Léonard MA, Lillicrap A, Norberg-King T, Whale G.

Aquat Toxicol. 2010 Apr 15;97(2):79-87. doi: 10.1016/j.aquatox.2009.12.008. Epub 2009 Dec 16. Review.

PMID:
20061034
5.

Strategies and tools for preventing neurotoxicity: to test, to predict and how to do it.

Llorens J, Li AA, Ceccatelli S, Suñol C.

Neurotoxicology. 2012 Aug;33(4):796-804. doi: 10.1016/j.neuro.2012.01.019. Epub 2012 Feb 7.

PMID:
22342764
6.

Developmental toxicology: new directions workshop: refining testing strategies and study designs.

Brannen KC, Fenton SE, Hansen DK, Harrouk W, Kim JH, Shuey D.

Birth Defects Res B Dev Reprod Toxicol. 2011 Oct;92(5):404-12. doi: 10.1002/bdrb.20326.

7.

The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity.

Amacher DE.

Toxicol Appl Pharmacol. 2010 May 15;245(1):134-42. doi: 10.1016/j.taap.2010.02.011. Epub 2010 Feb 26. Review.

PMID:
20219512
8.
9.

Incidence and nature of testicular toxicity findings in pharmaceutical development.

Sasaki JC, Chapin RE, Hall DG, Breslin W, Moffit J, Saldutti L, Enright B, Seger M, Jarvi K, Hixon M, Mitchard T, Kim JH.

Birth Defects Res B Dev Reprod Toxicol. 2011 Dec;92(6):511-25. doi: 10.1002/bdrb.20338. Review.

PMID:
22162370
10.

Prospects for reducing and refining the use of dogs in the regulatory toxicity testing of pharmaceuticals.

Broadhead CL, Betton G, Combes R, Damment S, Everett D, Garner C, Godsafe Z, Healing G, Heywood R, Jennings M, Lumley C, Oliver G, Smith D, Straughan D, Topham J, Wallis R, Wilson S, Buckley P.

Hum Exp Toxicol. 2000 Aug;19(8):440-7. Review.

PMID:
11125714
11.

Novel technologies and an overall strategy to allow hazard assessment and risk prediction of chemicals, cosmetics, and drugs with animal-free methods.

Leist M, Lidbury BA, Yang C, Hayden PJ, Kelm JM, Ringeissen S, Detroyer A, Meunier JR, Rathman JF, Jackson GR Jr, Stolper G, Hasiwa N.

ALTEX. 2012;29(4):373-88.

13.

Preparation of rodent testis co-cultures.

Wegner S, Hong S, Yu X, Faustman EM.

Curr Protoc Toxicol. 2013 Feb;Chapter 16:Unit 16.10. doi: 10.1002/0471140856.tx1610s55.

14.
15.

[INVITOX 2002: 12th International workshop on in vitro toxicology].

Boess F, Scholz G, Spielman H.

ALTEX. 2003;20(1):36-9. German. No abstract available.

PMID:
12674101
17.

Testicular and germ cell toxicity: in vitro approaches.

Lamb JC 4th, Chapin RE.

Reprod Toxicol. 1993;7 Suppl 1:17-22. Review.

PMID:
8400636
18.

Opportunities to integrate new approaches in genetic toxicology: an ILSI-HESI workshop report.

Zeiger E, Gollapudi B, Aardema MJ, Auerbach S, Boverhof D, Custer L, Dedon P, Honma M, Ishida S, Kasinski AL, Kim JH, Manjanatha MG, Marlowe J, Pfuhler S, Pogribny I, Slikker W, Stankowski LF Jr, Tanir JY, Tice R, van Benthem J, White P, Witt KL, Thybaud V.

Environ Mol Mutagen. 2015 Apr;56(3):277-85. doi: 10.1002/em.21923. Epub 2014 Dec 6.

19.

Meeting report: alternatives for developmental neurotoxicity testing.

Lein P, Locke P, Goldberg A.

Environ Health Perspect. 2007 May;115(5):764-8. Epub 2007 Jan 29.

20.

Alternative test methods in inhalation toxicology: challenges and opportunities.

Costa DL.

Exp Toxicol Pathol. 2008 Jun;60(2-3):105-9. doi: 10.1016/j.etp.2008.01.001. Epub 2008 May 16.

PMID:
18486462
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