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Results: 1 to 20 of 95

1.

Targeting cell motility in pulmonary arterial hypertension.

Paulin R, Meloche J, Courboulin A, Lambert C, Haromy A, Courchesne A, Bonnet P, Provencher S, Michelakis ED, Bonnet S.

Eur Respir J. 2014 Feb;43(2):531-44. doi: 10.1183/09031936.00181312. Epub 2013 Jul 11.

PMID:
23845719
[PubMed - in process]
2.

Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology.

Meloche J, Courchesne A, Barrier M, Carter S, Bisserier M, Paulin R, Lauzon-Joset JF, Breuils-Bonnet S, Tremblay É, Biardel S, Racine C, Courture C, Bonnet P, Majka SM, Deshaies Y, Picard F, Provencher S, Bonnet S.

J Am Heart Assoc. 2013 Jan 16;2(1):e005157. doi: 10.1161/JAHA.112.005157.

PMID:
23525442
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension.

Paulin R, Meloche J, Jacob MH, Bisserier M, Courboulin A, Bonnet S.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1798-809. doi: 10.1152/ajpheart.00654.2011. Epub 2011 Sep 2.

PMID:
21890685
[PubMed - indexed for MEDLINE]
Free Article
4.

Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH.

Courboulin A, Barrier M, Perreault T, Bonnet P, Tremblay VL, Paulin R, Tremblay E, Lambert C, Jacob MH, Bonnet SN, Provencher S, Bonnet S.

Eur Respir J. 2012 Sep;40(3):618-29. doi: 10.1183/09031936.00084211. Epub 2012 Apr 10.

PMID:
22496325
[PubMed - indexed for MEDLINE]
Free Article
5.

183 Novel OPG Protein Interactions Regulate Survival, Proliferation And Pah-associated Gene Expression in Pulmonary Arterial Smooth Muscle Cells.

Dawson S, Pickworth J, Rothman A, Iremonger J, Arnold N, Lawrie A.

Heart. 2014 Jun;100 Suppl 3:A102-3. doi: 10.1136/heartjnl-2014-306118.183.

PMID:
24922757
[PubMed - in process]
6.

Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis.

McMurtry MS, Bonnet S, Wu X, Dyck JR, Haromy A, Hashimoto K, Michelakis ED.

Circ Res. 2004 Oct 15;95(8):830-40. Epub 2004 Sep 16.

PMID:
15375007
[PubMed - indexed for MEDLINE]
Free Article
7.

Role for DNA damage signaling in pulmonary arterial hypertension.

Meloche J, Pflieger A, Vaillancourt M, Paulin R, Potus F, Zervopoulos S, Graydon C, Courboulin A, Breuils-Bonnet S, Tremblay E, Couture C, Michelakis ED, Provencher S, Bonnet S.

Circulation. 2014 Feb 18;129(7):786-97. doi: 10.1161/CIRCULATIONAHA.113.006167. Epub 2013 Nov 22.

PMID:
24270264
[PubMed - indexed for MEDLINE]
8.

Involvement of the bone morphogenetic protein system in endothelin- and aldosterone-induced cell proliferation of pulmonary arterial smooth muscle cells isolated from human patients with pulmonary arterial hypertension.

Yamanaka R, Otsuka F, Nakamura K, Yamashita M, Otani H, Takeda M, Matsumoto Y, Kusano KF, Ito H, Makino H.

Hypertens Res. 2010 May;33(5):435-45. doi: 10.1038/hr.2010.16. Epub 2010 Feb 26.

PMID:
20186146
[PubMed - indexed for MEDLINE]
9.

Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension.

Courboulin A, Tremblay VL, Barrier M, Meloche J, Jacob MH, Chapolard M, Bisserier M, Paulin R, Lambert C, Provencher S, Bonnet S.

Respir Res. 2011 Sep 27;12:128. doi: 10.1186/1465-9921-12-128.

PMID:
21951574
[PubMed - indexed for MEDLINE]
Free PMC Article
10.
11.

Role of Src tyrosine kinases in experimental pulmonary hypertension.

Pullamsetti SS, Berghausen EM, Dabral S, Tretyn A, Butrous E, Savai R, Butrous G, Dahal BK, Brandes RP, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Rosenkranz S, Schermuly RT.

Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1354-65. doi: 10.1161/ATVBAHA.112.248500. Epub 2012 Apr 19.

PMID:
22516066
[PubMed - indexed for MEDLINE]
Free Article
12.

Glycogen synthase kinase 3beta contributes to proliferation of arterial smooth muscle cells in pulmonary hypertension.

Sklepkiewicz P, Schermuly RT, Tian X, Ghofrani HA, Weissmann N, Sedding D, Kashour T, Seeger W, Grimminger F, Pullamsetti SS.

PLoS One. 2011 Apr 18;6(4):e18883. doi: 10.1371/journal.pone.0018883.

PMID:
21533110
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Sildenafil potentiates bone morphogenetic protein signaling in pulmonary arterial smooth muscle cells and in experimental pulmonary hypertension.

Yang J, Li X, Al-Lamki RS, Wu C, Weiss A, Berk J, Schermuly RT, Morrell NW.

Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):34-42. doi: 10.1161/ATVBAHA.112.300121. Epub 2012 Nov 8.

PMID:
23139294
[PubMed - indexed for MEDLINE]
Free Article
14.

Fluoxetine protects against monocrotaline-induced pulmonary arterial hypertension: potential roles of induction of apoptosis and upregulation of Kv1.5 channels in rats.

Zhai FG, Zhang XH, Wang HL.

Clin Exp Pharmacol Physiol. 2009 Aug;36(8):850-6. doi: 10.1111/j.1440-1681.2009.05168.x. Epub 2009 Mar 2.

PMID:
19298536
[PubMed - indexed for MEDLINE]
15.

Enhancer of zeste homolog 2 induces pulmonary artery smooth muscle cell proliferation.

Aljubran SA, Cox R Jr, Tamarapu Parthasarathy P, Kollongod Ramanathan G, Rajanbabu V, Bao H, Mohapatra SS, Lockey R, Kolliputi N.

PLoS One. 2012;7(5):e37712. doi: 10.1371/journal.pone.0037712. Epub 2012 May 25. Erratum in: PLoS One. 2012;7(8). doi: 10.1371/annotation/8580b50a-1556-4c86-aeb6-a88af839297a. Mohapatra, Shyam M [corrected to Mohapatra, Shyam S].

PMID:
22662197
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration.

Pullamsetti S, Krick S, Yilmaz H, Ghofrani HA, Schudt C, Weissmann N, Fuchs B, Seeger W, Grimminger F, Schermuly RT.

Respir Res. 2005 Nov 1;6:128.

PMID:
16262900
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.

Bonnet S, Rochefort G, Sutendra G, Archer SL, Haromy A, Webster L, Hashimoto K, Bonnet SN, Michelakis ED.

Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11418-23. Epub 2007 Jun 27.

PMID:
17596340
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension.

Perros F, Montani D, Dorfmüller P, Durand-Gasselin I, Tcherakian C, Le Pavec J, Mazmanian M, Fadel E, Mussot S, Mercier O, Hervé P, Emilie D, Eddahibi S, Simonneau G, Souza R, Humbert M.

Am J Respir Crit Care Med. 2008 Jul 1;178(1):81-8. doi: 10.1164/rccm.200707-1037OC. Epub 2008 Apr 17.

PMID:
18420966
[PubMed - indexed for MEDLINE]
19.

Sodium butyrate inhibits platelet-derived growth factor-induced proliferation and migration in pulmonary artery smooth muscle cells through Akt inhibition.

Cantoni S, Galletti M, Zambelli F, Valente S, Ponti F, Tassinari R, Pasquinelli G, Galiè N, Ventura C.

FEBS J. 2013 May;280(9):2042-55. doi: 10.1111/febs.12227. Epub 2013 Mar 28.

PMID:
23463962
[PubMed - indexed for MEDLINE]
20.

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