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Results: 1 to 20 of 170

1.

Henryin, an ent-kaurane diterpenoid, inhibits Wnt signaling through interference with β-catenin/TCF4 interaction in colorectal cancer cells.

Li X, Pu J, Jiang S, Su J, Kong L, Mao B, Sun H, Li Y.

PLoS One. 2013 Jul 2;8(7):e68525. doi: 10.1371/journal.pone.0068525. Print 2013.

PMID:
23844215
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.

Yeh CT, Rao YK, Ye M, Wu WS, Chang TC, Wang LS, Wu CH, Wu AT, Tzeng YM.

Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41. doi: 10.1016/j.taap.2012.03.007. Epub 2012 Mar 23.

PMID:
22465936
[PubMed - indexed for MEDLINE]
3.

Structure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction.

Tian W, Han X, Yan M, Xu Y, Duggineni S, Lin N, Luo G, Li YM, Han X, Huang Z, An J.

Biochemistry. 2012 Jan 17;51(2):724-31. doi: 10.1021/bi201428h. Epub 2012 Jan 6.

PMID:
22224445
[PubMed - indexed for MEDLINE]
4.

Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes.

Schepeler T, Holm A, Halvey P, Nordentoft I, Lamy P, Riising EM, Christensen LL, Thorsen K, Liebler DC, Helin K, Ørntoft TF, Andersen CL.

Oncogene. 2012 May 31;31(22):2750-60. doi: 10.1038/onc.2011.453. Epub 2011 Oct 3.

PMID:
21963845
[PubMed - indexed for MEDLINE]
5.

A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/β-catenin signaling and colon cancer cell tumorigenesis.

Wang W, Liu H, Wang S, Hao X, Li L.

Cell Res. 2011 May;21(5):730-40. doi: 10.1038/cr.2011.30. Epub 2011 Feb 15.

PMID:
21321609
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Wnt/β-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells.

Konsavage WM Jr, Kyler SL, Rennoll SA, Jin G, Yochum GS.

J Biol Chem. 2012 Apr 6;287(15):11730-9. doi: 10.1074/jbc.M111.327767. Epub 2012 Feb 15.

PMID:
22337891
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer.

Chan DW, Mak CS, Leung TH, Chan KK, Ngan HY.

Oncotarget. 2012 Dec;3(12):1546-56.

PMID:
23295859
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Context-dependent activation of Wnt signaling by tumor suppressor RUNX3 in gastric cancer cells.

Ju X, Ishikawa TO, Naka K, Ito K, Ito Y, Oshima M.

Cancer Sci. 2014 Apr;105(4):418-24. doi: 10.1111/cas.12356. Epub 2014 Feb 18.

PMID:
24447505
[PubMed - indexed for MEDLINE]
9.

Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/β-catenin pathway in human cancer.

Zhang Y, Toh L, Lau P, Wang X.

J Biol Chem. 2012 Sep 21;287(39):32494-511. Epub 2012 Jul 31.

PMID:
22854964
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

p15RS attenuates Wnt/{beta}-catenin signaling by disrupting {beta}-catenin·TCF4 Interaction.

Wu Y, Zhang Y, Zhang H, Yang X, Wang Y, Ren F, Liu H, Zhai Y, Jia B, Yu J, Chang Z.

J Biol Chem. 2010 Nov 5;285(45):34621-31. doi: 10.1074/jbc.M110.148791. Epub 2010 Aug 25.

PMID:
20739273
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Phospholipase D1 drives a positive feedback loop to reinforce the Wnt/beta-catenin/TCF signaling axis.

Kang DW, Lee SH, Yoon JW, Park WS, Choi KY, Min do S.

Cancer Res. 2010 May 15;70(10):4233-42. doi: 10.1158/0008-5472.CAN-09-3470. Epub 2010 May 4.

PMID:
20442281
[PubMed - indexed for MEDLINE]
Free Article
12.

Reg4-induced mitogenesis involves Akt-GSK3β-β-Catenin-TCF-4 signaling in human colorectal cancer.

Bishnupuri KS, Sainathan SK, Bishnupuri K, Leahy DR, Luo Q, Anant S, Houchen CW, Dieckgraefe BK.

Mol Carcinog. 2014 Feb;53 Suppl 1:E169-80. doi: 10.1002/mc.22088. Epub 2013 Oct 22.

PMID:
24151146
[PubMed - indexed for MEDLINE]
13.

Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo.

Wei W, Chua MS, Grepper S, So S.

Int J Cancer. 2010 May 15;126(10):2426-36. doi: 10.1002/ijc.24810.

PMID:
19662654
[PubMed - indexed for MEDLINE]
14.

The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells.

Ungerbäck J, Elander N, Grünberg J, Sigvardsson M, Söderkvist P.

PLoS One. 2011 Mar 18;6(3):e17957. doi: 10.1371/journal.pone.0017957.

PMID:
21437251
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.

Mahmoudi T, Boj SF, Hatzis P, Li VS, Taouatas N, Vries RG, Teunissen H, Begthel H, Korving J, Mohammed S, Heck AJ, Clevers H.

PLoS Biol. 2010 Nov 16;8(11):e1000539. doi: 10.1371/journal.pbio.1000539.

PMID:
21103407
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells.

He L, Lu N, Dai Q, Zhao Y, Zhao L, Wang H, Li Z, You Q, Guo Q.

Toxicology. 2013 Oct 4;312:36-47. doi: 10.1016/j.tox.2013.07.013. Epub 2013 Jul 30. Review.

PMID:
23907061
[PubMed - indexed for MEDLINE]
17.

Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells.

Chakraborty PK, Lee WK, Molitor M, Wolff NA, Thévenod F.

Mol Cancer. 2010 May 8;9:102. doi: 10.1186/1476-4598-9-102.

PMID:
20459685
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells.

Wei W, Chua MS, Grepper S, So SK.

Mol Cancer. 2009 Sep 24;8:76. doi: 10.1186/1476-4598-8-76.

PMID:
19778454
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

NGX6 inhibits cell invasion and adhesion through suppression of Wnt/beta-catenin signal pathway in colon cancer.

Guo Q, Shen S, Liao M, Lian P, Wang X.

Acta Biochim Biophys Sin (Shanghai). 2010 Jul;42(7):450-6. doi: 10.1093/abbs/gmq049. Epub 2010 Jun 13.

PMID:
20705583
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

β-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells.

Satow R, Shitashige M, Jigami T, Fukami K, Honda K, Kitabayashi I, Yamada T.

Gastroenterology. 2012 Mar;142(3):572-81. doi: 10.1053/j.gastro.2011.11.041. Epub 2011 Dec 9.

PMID:
22155184
[PubMed - indexed for MEDLINE]

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