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Results: 1 to 20 of 119

1.

Naphthyridinomycin biosynthesis revealing the use of leader peptide to guide nonribosomal peptide assembly.

Pu JY, Peng C, Tang MC, Zhang Y, Guo JP, Song LQ, Hua Q, Tang GL.

Org Lett. 2013 Jul 19;15(14):3674-7. doi: 10.1021/ol401549y. Epub 2013 Jul 10.

PMID:
23841701
[PubMed - indexed for MEDLINE]
2.

Hijacking a hydroxyethyl unit from a central metabolic ketose into a nonribosomal peptide assembly line.

Peng C, Pu JY, Song LQ, Jian XH, Tang MC, Tang GL.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8540-5. doi: 10.1073/pnas.1204232109. Epub 2012 May 14.

PMID:
22586110
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: a novel function for a nonribosomal peptide synthetase.

Koketsu K, Minami A, Watanabe K, Oguri H, Oikawa H.

Methods Enzymol. 2012;516:79-98. doi: 10.1016/B978-0-12-394291-3.00026-5.

PMID:
23034225
[PubMed - indexed for MEDLINE]
5.

Molecular cloning and analysis of the ergopeptine assembly system in the ergot fungus Claviceps purpurea.

Correia T, Grammel N, Ortel I, Keller U, Tudzynski P.

Chem Biol. 2003 Dec;10(12):1281-92.

PMID:
14700635
[PubMed - indexed for MEDLINE]
Free Article
6.

BlmIII and BlmIV nonribosomal peptide synthetase-catalyzed biosynthesis of the bleomycin bithiazole moiety involving both in cis and in trans aminoacylation.

Du L, Chen M, Zhang Y, Shen B.

Biochemistry. 2003 Aug 19;42(32):9731-40.

PMID:
12911315
[PubMed - indexed for MEDLINE]
7.

An iterative nonribosomal peptide synthetase assembles the pyrrole-amide antibiotic congocidine in Streptomyces ambofaciens.

Juguet M, Lautru S, Francou FX, Nezbedová S, Leblond P, Gondry M, Pernodet JL.

Chem Biol. 2009 Apr 24;16(4):421-31. doi: 10.1016/j.chembiol.2009.03.010.

PMID:
19389628
[PubMed - indexed for MEDLINE]
Free Article
8.

Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster.

Binz TM, Maffioli SI, Sosio M, Donadio S, Müller R.

J Biol Chem. 2010 Oct 22;285(43):32710-9. doi: 10.1074/jbc.M110.146803. Epub 2010 Aug 14.

PMID:
20710026
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Core assembly mechanism of quinocarcin/SF-1739: bimodular complex nonribosomal peptide synthetases for sequential mannich-type reactions.

Hiratsuka T, Koketsu K, Minami A, Kaneko S, Yamazaki C, Watanabe K, Oguri H, Oikawa H.

Chem Biol. 2013 Dec 19;20(12):1523-35. doi: 10.1016/j.chembiol.2013.10.011. Epub 2013 Nov 21.

PMID:
24269153
[PubMed - indexed for MEDLINE]
10.

Chapter 14. Biosynthesis of nonribosomal peptide precursors.

Wilkinson B, Micklefield J.

Methods Enzymol. 2009;458:353-78. doi: 10.1016/S0076-6879(09)04814-9.

PMID:
19374990
[PubMed - indexed for MEDLINE]
11.

A nonribosomal peptide synthetase gene tzw1 is involved in zwittermicin A biosynthesis in Bacillus thuringiensis G03.

Shao T, Bai L, Zhang J, Wang G, Liu D, Li Z, Liu J, Song F, Huang D.

Curr Microbiol. 2008 Jul;57(1):61-5. doi: 10.1007/s00284-008-9153-5. Epub 2008 Apr 30.

PMID:
18446411
[PubMed - indexed for MEDLINE]
12.

Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines.

Walsh CT, Chen H, Keating TA, Hubbard BK, Losey HC, Luo L, Marshall CG, Miller DA, Patel HM.

Curr Opin Chem Biol. 2001 Oct;5(5):525-34. Review.

PMID:
11578925
[PubMed - indexed for MEDLINE]
13.

Structure elucidation and biosynthesis of fuscachelins, peptide siderophores from the moderate thermophile Thermobifida fusca.

Dimise EJ, Widboom PF, Bruner SD.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15311-6. doi: 10.1073/pnas.0805451105. Epub 2008 Oct 1.

PMID:
18832174
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Nostophycin biosynthesis is directed by a hybrid polyketide synthase-nonribosomal peptide synthetase in the toxic cyanobacterium Nostoc sp. strain 152.

Fewer DP, Osterholm J, Rouhiainen L, Jokela J, Wahlsten M, Sivonen K.

Appl Environ Microbiol. 2011 Nov;77(22):8034-40. doi: 10.1128/AEM.05993-11. Epub 2011 Sep 23.

PMID:
21948844
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Insights into the biosynthesis of hormaomycin, an exceptionally complex bacterial signaling metabolite.

Höfer I, Crüsemann M, Radzom M, Geers B, Flachshaar D, Cai X, Zeeck A, Piel J.

Chem Biol. 2011 Mar 25;18(3):381-91. doi: 10.1016/j.chembiol.2010.12.018.

PMID:
21439483
[PubMed - indexed for MEDLINE]
Free Article
16.

Activation of a silent fungal polyketide biosynthesis pathway through regulatory cross talk with a cryptic nonribosomal peptide synthetase gene cluster.

Bergmann S, Funk AN, Scherlach K, Schroeckh V, Shelest E, Horn U, Hertweck C, Brakhage AA.

Appl Environ Microbiol. 2010 Dec;76(24):8143-9. doi: 10.1128/AEM.00683-10. Epub 2010 Oct 15.

PMID:
20952652
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The linear pentadecapeptide gramicidin is assembled by four multimodular nonribosomal peptide synthetases that comprise 16 modules with 56 catalytic domains.

Kessler N, Schuhmann H, Morneweg S, Linne U, Marahiel MA.

J Biol Chem. 2004 Feb 27;279(9):7413-9. Epub 2003 Dec 11.

PMID:
14670971
[PubMed - indexed for MEDLINE]
Free Article
18.

Myxovirescin A biosynthesis is directed by hybrid polyketide synthases/nonribosomal peptide synthetase, 3-hydroxy-3-methylglutaryl-CoA synthases, and trans-acting acyltransferases.

Simunovic V, Zapp J, Rachid S, Krug D, Meiser P, Müller R.

Chembiochem. 2006 Aug;7(8):1206-20.

PMID:
16835859
[PubMed - indexed for MEDLINE]
19.

Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins.

Moffitt MC, Neilan BA.

Appl Environ Microbiol. 2004 Nov;70(11):6353-62.

PMID:
15528492
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Substrate specificity of nonribosomal peptide synthetase modules responsible for the biosynthesis of the oligopeptide moiety of cephabacin in Lysobacter lactamgenus.

Demirev AV, Lee CH, Jaishy BP, Nam DH, Ryu DD.

FEMS Microbiol Lett. 2006 Feb;255(1):121-8.

PMID:
16436071
[PubMed - indexed for MEDLINE]

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