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Items: 1 to 20 of 92

1.

Influence and pathophysiological mechanisms of simvastatin on prostatic hyperplasia in spontaneously hypertensive rats.

Zhang X, Shen F, Dong L, Zhao X, Qu X.

Urol Int. 2013;91(4):467-73. doi: 10.1159/000350519. Epub 2013 Jul 6.

PMID:
23838355
2.

[Inhibitory effect of losartan on prostatic hyperplasia in spontaneous hypertension rats and its pathophysiological mechanism].

Shen F, Dong LN, Zhang XY, Zhao XK, Zeng XF, Qu XB.

Zhonghua Nan Ke Xue. 2012 Jul;18(7):600-5. Chinese.

PMID:
22994044
3.

Simvastatin ameliorates angiotensin II-induced endothelial dysfunction through restoration of Rho-BH4-eNOS-NO pathway.

Zhang Z, Wang M, Xue SJ, Liu DH, Tang YB.

Cardiovasc Drugs Ther. 2012 Feb;26(1):31-40. doi: 10.1007/s10557-011-6351-3.

PMID:
22083280
4.

Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms.

Kumar A, Sharma N, Gupta A, Kalonia H, Mishra J.

Brain Res. 2012 Aug 30;1471:13-22. doi: 10.1016/j.brainres.2012.06.050. Epub 2012 Jul 10.

PMID:
22789904
5.

Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury.

Li B, Mahmood A, Lu D, Wu H, Xiong Y, Qu C, Chopp M.

Neurosurgery. 2009 Jul;65(1):179-85; discussion 185-6. doi: 10.1227/01.NEU.0000346272.76537.DC.

6.

Simvastatin reduces mortality and hepatic injury after hemorrhage/resuscitation in rats.

Relja B, Lehnert M, Seyboth K, Bormann F, Höhn C, Czerny C, Henrich D, Marzi I.

Shock. 2010 Jul;34(1):46-54. doi: 10.1097/SHK.0b013e3181cd8d05.

PMID:
19997050
7.

Effects of chronic treatment with simvastatin on endothelial dysfunction in spontaneously hypertensive rats.

Alvarez de Sotomayor M, Pérez-Guerrero C, Herrera MD, Marhuenda E.

J Hypertens. 1999 Jun;17(6):769-76.

PMID:
10459874
8.

Simvastatin increases circulating endothelial progenitor cells and reduces the formation and progression of diabetic retinopathy in rats.

Zhang W, Yan H.

Exp Eye Res. 2012 Dec;105:1-8. doi: 10.1016/j.exer.2012.09.014. Epub 2012 Oct 8.

PMID:
23059402
9.

Simvastatin and losartan enhance nitric oxide and reduce oxidative stress in salt-induced hypertension.

Bayorh MA, Ganafa AA, Eatman D, Walton M, Feuerstein GZ.

Am J Hypertens. 2005 Nov;18(11):1496-502.

PMID:
16280288
10.
11.

[Simvastatin and ischemia-reperfusion damage: its effects on apoptotic myocyte death and on the endothelial expression of nitric-oxide synthetase in an experimental model of the isolated rat heart].

Di Napoli P, Maggi A, Spina R, Barsotti L, Taccardi AA, Stuppia L, Vianale G, Palka G, Barsotti A.

Cardiologia. 1999 Jan;44(1):69-74. Italian.

PMID:
10188333
12.

Protective mechanisms of simvastatin in experimental periodontal disease.

Dalcico R, de Menezes AM, Deocleciano OB, Oriá RB, Vale ML, Ribeiro RA, Brito GA.

J Periodontol. 2013 Aug;84(8):1145-57. doi: 10.1902/jop.2012.120114. Epub 2012 Nov 26.

PMID:
23181416
13.

Simvastatin prevents large blood pressure variability induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways.

Takayama N, Kai H, Kudo H, Yasuoka S, Mori T, Anegawa T, Koga M, Kajimoto H, Hirooka Y, Imaizumi T.

Hypertens Res. 2011 Mar;34(3):341-7. doi: 10.1038/hr.2010.229. Epub 2010 Dec 2.

PMID:
21124329
14.

Simvastatin suppresses the progression of experimentally induced cerebral aneurysms in rats.

Aoki T, Kataoka H, Ishibashi R, Nozaki K, Hashimoto N.

Stroke. 2008 Apr;39(4):1276-85. doi: 10.1161/STROKEAHA.107.503086. Epub 2008 Feb 28.

15.

Simvastatin suppresses experimental aortic aneurysm expansion.

Kalyanasundaram A, Elmore JR, Manazer JR, Golden A, Franklin DP, Galt SW, Zakhary EM, Carey DJ.

J Vasc Surg. 2006 Jan;43(1):117-24.

16.

Simvastatin inhibits cardiac hypertrophy and angiotensin-converting enzyme activity in rats with aortic stenosis.

Luo JD, Zhang WW, Zhang GP, Guan JX, Chen X.

Clin Exp Pharmacol Physiol. 1999 Nov;26(11):903-8.

PMID:
10561812
17.

Simvastatin reduces secondary brain injury caused by cortical contusion in rats: possible involvement of TLR4/NF-kappaB pathway.

Chen G, Zhang S, Shi J, Ai J, Qi M, Hang C.

Exp Neurol. 2009 Apr;216(2):398-406. doi: 10.1016/j.expneurol.2008.12.019. Epub 2009 Jan 7.

PMID:
19166837
18.

[Effects of simvastatin on the left ventricular hypertrophy in spontaneously hypertensive rats and its relationship with the expression of protein kinase B].

Zhao LY, Chen YQ, Zheng QS, Xue YS, Shang FJ, Li AG, Wang B.

Zhonghua Yi Xue Za Zhi. 2005 May 25;85(19):1344-7. Chinese.

PMID:
16029635
19.

AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.

Harada N, Shimozawa N, Okajima K.

Transl Res. 2009 Sep;154(3):142-52. doi: 10.1016/j.trsl.2009.06.004. Epub 2009 Jul 7.

PMID:
19665690
20.

Comparison of the effect of simvastatin, spironolactone and L-arginine on endothelial function of aorta in hereditary hypertriglyceridemic rats.

Török J, L'upták I, Matúsková J, Pechánová O, Zicha J, Kunes J, Simko F.

Physiol Res. 2007;56 Suppl 2:S33-40. Epub 2007 Sep 5.

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