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Results: 1 to 20 of 95

1.

Relaxin for treatment of acute heart failure: making the case for treating targeted patient profiles.

Hernandez-Montfort JA, Arora S, Slawsky MT.

Curr Heart Fail Rep. 2013 Sep;10(3):198-203. doi: 10.1007/s11897-013-0148-6. Review.

PMID:
23836112
[PubMed - indexed for MEDLINE]
2.

Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes.

Metra M, Cotter G, Davison BA, Felker GM, Filippatos G, Greenberg BH, Ponikowski P, Unemori E, Voors AA, Adams KF Jr, Dorobantu MI, Grinfeld L, Jondeau G, Marmor A, Masip J, Pang PS, Werdan K, Prescott MF, Edwards C, Teichman SL, Trapani A, Bush CA, Saini R, Schumacher C, Severin T, Teerlink JR; RELAX-AHF Investigators.

J Am Coll Cardiol. 2013 Jan 15;61(2):196-206. doi: 10.1016/j.jacc.2012.11.005.

PMID:
23273292
[PubMed - indexed for MEDLINE]
Free Article
3.

Permutation criteria to evaluate multiple clinical endpoints in a proof-of-concept study: lessons from Pre-RELAX-AHF.

Davison BA, Cotter G, Sun H, Chen L, Teerlink JR, Metra M, Felker GM, Voors AA, Ponikowski P, Filippatos G, Greenberg B, Teichman SL, Unemori E, Koch GG.

Clin Res Cardiol. 2011 Sep;100(9):745-53. doi: 10.1007/s00392-011-0304-5. Epub 2011 Mar 17.

PMID:
21416190
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial.

Teerlink JR, Cotter G, Davison BA, Felker GM, Filippatos G, Greenberg BH, Ponikowski P, Unemori E, Voors AA, Adams KF Jr, Dorobantu MI, Grinfeld LR, Jondeau G, Marmor A, Masip J, Pang PS, Werdan K, Teichman SL, Trapani A, Bush CA, Saini R, Schumacher C, Severin TM, Metra M; RELAXin in Acute Heart Failure (RELAX-AHF) Investigators.

Lancet. 2013 Jan 5;381(9860):29-39. doi: 10.1016/S0140-6736(12)61855-8. Epub 2012 Nov 7.

PMID:
23141816
[PubMed - indexed for MEDLINE]
5.

[What is new in the medical management of acute heart failure?].

Meyer P, White M, Keller RF, Lerch R, Hullin R.

Rev Med Suisse. 2010 Jun 9;6(252):1211-7. Review. French.

PMID:
20614757
[PubMed - indexed for MEDLINE]
6.

Relaxin, a pleiotropic vasodilator for the treatment of heart failure.

Teichman SL, Unemori E, Dschietzig T, Conrad K, Voors AA, Teerlink JR, Felker GM, Metra M, Cotter G.

Heart Fail Rev. 2009 Dec;14(4):321-9. doi: 10.1007/s10741-008-9129-3. Epub 2008 Dec 20. Review.

PMID:
19101795
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Design of the RELAXin in acute heart failure study.

Ponikowski P, Metra M, Teerlink JR, Unemori E, Felker GM, Voors AA, Filippatos G, Greenberg B, Teichman SL, Severin T, Mueller-Velten G, Cotter G, Davison BA.

Am Heart J. 2012 Feb;163(2):149-55.e1. doi: 10.1016/j.ahj.2011.10.009.

PMID:
22305830
[PubMed - indexed for MEDLINE]
8.

Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study.

Teerlink JR, Metra M, Felker GM, Ponikowski P, Voors AA, Weatherley BD, Marmor A, Katz A, Grzybowski J, Unemori E, Teichman SL, Cotter G.

Lancet. 2009 Apr 25;373(9673):1429-39. doi: 10.1016/S0140-6736(09)60622-X. Epub 2009 Mar 28.

PMID:
19329178
[PubMed - indexed for MEDLINE]
9.

Medical therapy for acute decompensated heart failure: what recent clinical trials have taught us about diuretics and vasodilators.

Marti C, Cole R, Kalogeropoulos A, Georgiopoulou V, Butler J.

Curr Heart Fail Rep. 2012 Mar;9(1):1-7. doi: 10.1007/s11897-011-0072-6. Review.

PMID:
21874282
[PubMed - indexed for MEDLINE]
10.

Acute heart failure: lessons learned so far.

Howlett JG.

Can J Cardiol. 2011 May-Jun;27(3):284-95. doi: 10.1016/j.cjca.2011.02.007. Review.

PMID:
21601768
[PubMed - indexed for MEDLINE]
11.

Tezosentan in patients with acute heart failure: design of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Study (VERITAS).

Teerlink JR, McMurray JJ, Bourge RC, Cleland JG, Cotter G, Jondeau G, Krum H, Metra M, O'Connor CM, Parker JD, Torre-Amione G, Van Veldhuisen DJ, Frey A, Rainisio M, Kobrin I; VERITAS Investigators.

Am Heart J. 2005 Jul;150(1):46-53.

PMID:
16084150
[PubMed - indexed for MEDLINE]
12.

Vasodilators in the treatment of acute heart failure: what we know, what we don't.

Metra M, Teerlink JR, Voors AA, Felker GM, Milo-Cotter O, Weatherley B, Dittrich H, Cotter G.

Heart Fail Rev. 2009 Dec;14(4):299-307. doi: 10.1007/s10741-008-9127-5. Epub 2008 Dec 19. Review.

PMID:
19096932
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Novel pharmacologic therapies in development for acute decompensated heart failure.

Ezekowitz JA.

Curr Cardiol Rep. 2013 Feb;15(2):329. doi: 10.1007/s11886-012-0329-z. Review.

PMID:
23314727
[PubMed - indexed for MEDLINE]
14.

Early drop in systolic blood pressure and worsening renal function in acute heart failure: renal results of Pre-RELAX-AHF.

Voors AA, Davison BA, Felker GM, Ponikowski P, Unemori E, Cotter G, Teerlink JR, Greenberg BH, Filippatos G, Teichman SL, Metra M; Pre-RELAX-AHF study group.

Eur J Heart Fail. 2011 Sep;13(9):961-7. doi: 10.1093/eurjhf/hfr060. Epub 2011 May 28.

PMID:
21622980
[PubMed - indexed for MEDLINE]
15.

Recent developments in the treatment of heart failure: highlights from the American Heart Association's Scientific Sessions, Los Angeles, California, 3 - 7 December 2012.

von Haehling S.

Expert Opin Investig Drugs. 2013 Jul;22(7):933-7. doi: 10.1517/13543784.2013.798301. Epub 2013 May 9.

PMID:
23656525
[PubMed - indexed for MEDLINE]
16.

Advancing care for acute heart failure--no time to relax.

Hernandez AF, Granger CB.

Lancet. 2009 Apr 25;373(9673):1401-2. doi: 10.1016/S0140-6736(09)60653-X. Epub 2009 Mar 28. No abstract available.

PMID:
19329180
[PubMed - indexed for MEDLINE]
17.

Acute decompensated heart failure: update on new and emerging evidence and directions for future research.

Givertz MM, Teerlink JR, Albert NM, Westlake Canary CA, Collins SP, Colvin-Adams M, Ezekowitz JA, Fang JC, Hernandez AF, Katz SD, Krishnamani R, Stough WG, Walsh MN, Butler J, Carson PE, Dimarco JP, Hershberger RE, Rogers JG, Spertus JA, Stevenson WG, Sweitzer NK, Tang WH, Starling RC.

J Card Fail. 2013 Jun;19(6):371-89. doi: 10.1016/j.cardfail.2013.04.002. Review.

PMID:
23743486
[PubMed - indexed for MEDLINE]
18.

Relaxin-2 may offer therapeutic advantages in end-stage heart failure.

Zhao Z, Liu T, Li G.

Int J Cardiol. 2012 Jun 14;157(3):432-3. doi: 10.1016/j.ijcard.2012.03.169. Epub 2012 Apr 27. No abstract available.

PMID:
22541981
[PubMed - indexed for MEDLINE]
19.

Overview of randomized clinical trials in acute heart failure syndromes.

Teerlink JR.

Am J Cardiol. 2005 Sep 19;96(6A):59G-67G. Review.

PMID:
16181824
[PubMed - indexed for MEDLINE]
20.

Relaxin: a new approach for the treatment of acute congestive heart failure.

Grossman J, Frishman WH.

Cardiol Rev. 2010 Nov-Dec;18(6):305-12. doi: 10.1097/CRD.0b013e3181f493e3. Review.

PMID:
20926940
[PubMed - indexed for MEDLINE]

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