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Items: 1 to 20 of 133


An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants.

Cao M, Liu X, Zhang Y, Xue X, Zhou XE, Melcher K, Gao P, Wang F, Zeng L, Zhao Y, Zhao Y, Deng P, Zhong D, Zhu JK, Xu HE, Xu Y.

Cell Res. 2013 Aug;23(8):1043-54. doi: 10.1038/cr.2013.95. Epub 2013 Jul 9.


Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance.

Okamoto M, Peterson FC, Defries A, Park SY, Endo A, Nambara E, Volkman BF, Cutler SR.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12132-7. doi: 10.1073/pnas.1305919110. Epub 2013 Jul 1.


Tomato PYR/PYL/RCAR abscisic acid receptors show high expression in root, differential sensitivity to the abscisic acid agonist quinabactin, and the capability to enhance plant drought resistance.

González-Guzmán M, Rodríguez L, Lorenzo-Orts L, Pons C, Sarrión-Perdigones A, Fernández MA, Peirats-Llobet M, Forment J, Moreno-Alvero M, Cutler SR, Albert A, Granell A, Rodríguez PL.

J Exp Bot. 2014 Aug;65(15):4451-64. doi: 10.1093/jxb/eru219. Epub 2014 May 26.


A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.

Melcher K, Ng LM, Zhou XE, Soon FF, Xu Y, Suino-Powell KM, Park SY, Weiner JJ, Fujii H, Chinnusamy V, Kovach A, Li J, Wang Y, Li J, Peterson FC, Jensen DR, Yong EL, Volkman BF, Cutler SR, Zhu JK, Xu HE.

Nature. 2009 Dec 3;462(7273):602-8. doi: 10.1038/nature08613.


Modulation of abscisic acid signaling in vivo by an engineered receptor-insensitive protein phosphatase type 2C allele.

Dupeux F, Antoni R, Betz K, Santiago J, Gonzalez-Guzman M, Rodriguez L, Rubio S, Park SY, Cutler SR, Rodriguez PL, Márquez JA.

Plant Physiol. 2011 May;156(1):106-16. doi: 10.1104/pp.110.170894. Epub 2011 Feb 28.


Enhancement of abscisic acid sensitivity and reduction of water consumption in Arabidopsis by combined inactivation of the protein phosphatases type 2C ABI1 and HAB1.

Saez A, Robert N, Maktabi MH, Schroeder JI, Serrano R, Rodriguez PL.

Plant Physiol. 2006 Aug;141(4):1389-99. Epub 2006 Jun 23.


Unique drought resistance functions of the highly ABA-induced clade A protein phosphatase 2Cs.

Bhaskara GB, Nguyen TT, Verslues PE.

Plant Physiol. 2012 Sep;160(1):379-95. doi: 10.1104/pp.112.202408. Epub 2012 Jul 24.


The unique mode of action of a divergent member of the ABA-receptor protein family in ABA and stress signaling.

Zhao Y, Chan Z, Xing L, Liu X, Hou YJ, Chinnusamy V, Wang P, Duan C, Zhu JK.

Cell Res. 2013 Dec;23(12):1380-95. doi: 10.1038/cr.2013.149. Epub 2013 Nov 5.


Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.

Santiago J, Rodrigues A, Saez A, Rubio S, Antoni R, Dupeux F, Park SY, Márquez JA, Cutler SR, Rodriguez PL.

Plant J. 2009 Nov;60(4):575-88. doi: 10.1111/j.1365-313X.2009.03981.x. Epub 2009 Jul 16.


Designed abscisic acid analogs as antagonists of PYL-PP2C receptor interactions.

Takeuchi J, Okamoto M, Akiyama T, Muto T, Yajima S, Sue M, Seo M, Kanno Y, Kamo T, Endo A, Nambara E, Hirai N, Ohnishi T, Cutler SR, Todoroki Y.

Nat Chem Biol. 2014 Jun;10(6):477-82. doi: 10.1038/nchembio.1524. Epub 2014 May 4.


Structural basis of abscisic acid signalling.

Miyazono K, Miyakawa T, Sawano Y, Kubota K, Kang HJ, Asano A, Miyauchi Y, Takahashi M, Zhi Y, Fujita Y, Yoshida T, Kodaira KS, Yamaguchi-Shinozaki K, Tanokura M.

Nature. 2009 Dec 3;462(7273):609-14. doi: 10.1038/nature08583.


Functional roles of the protein phosphatase 2C, AtAIP1, in abscisic acid signaling and sugar tolerance in Arabidopsis.

Lim CW, Kim JH, Baek W, Kim BS, Lee SC.

Plant Sci. 2012 May;187:83-8. doi: 10.1016/j.plantsci.2012.01.013. Epub 2012 Feb 3.


Thirsty plants and beyond: structural mechanisms of abscisic acid perception and signaling.

Melcher K, Zhou XE, Xu HE.

Curr Opin Struct Biol. 2010 Dec;20(6):722-9. doi: 10.1016/ Epub 2010 Oct 14. Review.


Complex structures of the abscisic acid receptor PYL3/RCAR13 reveal a unique regulatory mechanism.

Zhang X, Zhang Q, Xin Q, Yu L, Wang Z, Wu W, Jiang L, Wang G, Tian W, Deng Z, Wang Y, Liu Z, Long J, Gong Z, Chen Z.

Structure. 2012 May 9;20(5):780-90. doi: 10.1016/j.str.2012.02.019.


Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.

Soon FF, Ng LM, Zhou XE, West GM, Kovach A, Tan MH, Suino-Powell KM, He Y, Xu Y, Chalmers MJ, Brunzelle JS, Zhang H, Yang H, Jiang H, Li J, Yong EL, Cutler S, Zhu JK, Griffin PR, Melcher K, Xu HE.

Science. 2012 Jan 6;335(6064):85-8. doi: 10.1126/science.1215106. Epub 2011 Nov 24.


Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins.

Park SY, Fung P, Nishimura N, Jensen DR, Fujii H, Zhao Y, Lumba S, Santiago J, Rodrigues A, Chow TF, Alfred SE, Bonetta D, Finkelstein R, Provart NJ, Desveaux D, Rodriguez PL, McCourt P, Zhu JK, Schroeder JI, Volkman BF, Cutler SR.

Science. 2009 May 22;324(5930):1068-71. doi: 10.1126/science.1173041. Epub 2009 Apr 30.


FAR-RED ELONGATED HYPOCOTYL3 and FAR-RED IMPAIRED RESPONSE1 transcription factors integrate light and abscisic acid signaling in Arabidopsis.

Tang W, Ji Q, Huang Y, Jiang Z, Bao M, Wang H, Lin R.

Plant Physiol. 2013 Oct;163(2):857-66. doi: 10.1104/pp.113.224386. Epub 2013 Aug 14.


Regulators of PP2C phosphatase activity function as abscisic acid sensors.

Ma Y, Szostkiewicz I, Korte A, Moes D, Yang Y, Christmann A, Grill E.

Science. 2009 May 22;324(5930):1064-8. doi: 10.1126/science.1172408. Epub 2009 Apr 30.


The molecular basis of ABA-independent inhibition of PP2Cs by a subclass of PYL proteins.

Hao Q, Yin P, Li W, Wang L, Yan C, Lin Z, Wu JZ, Wang J, Yan SF, Yan N.

Mol Cell. 2011 Jun 10;42(5):662-72. doi: 10.1016/j.molcel.2011.05.011.


Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation.

Mosquna A, Peterson FC, Park SY, Lozano-Juste J, Volkman BF, Cutler SR.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20838-43. doi: 10.1073/pnas.1112838108. Epub 2011 Dec 2.

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