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Results: 1 to 20 of 78

1.

An update of animal models of Alzheimer disease with a reevaluation of plaque depositions.

Lee JE, Han PL.

Exp Neurobiol. 2013 Jun;22(2):84-95. doi: 10.5607/en.2013.22.2.84. Epub 2013 Jun 27.

PMID:
23833557
[PubMed]
Free PMC Article
2.

Analysis of differential plaque depositions in the brains of Tg2576 and Tg-APPswe/PS1dE9 transgenic mouse models of Alzheimer disease.

Kim TK, Lee JE, Park SK, Lee KW, Seo JS, Im JY, Kim ST, Lee JY, Kim YH, Lee JK, Han PL.

Exp Mol Med. 2012 Aug 31;44(8):492-502. doi: 10.3858/emm.2012.44.8.056.

PMID:
22644036
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice.

Zhang W, Zhang W, Li Z, Hao J, Zhang Z, Liu L, Mao N, Miao J, Zhang L.

Pharmacol Biochem Behav. 2012 Jan;100(3):361-9. doi: 10.1016/j.pbb.2011.09.012. Epub 2011 Oct 2.

PMID:
21993310
[PubMed - indexed for MEDLINE]
4.

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease.

Garcia-Alloza M, Robbins EM, Zhang-Nunes SX, Purcell SM, Betensky RA, Raju S, Prada C, Greenberg SM, Bacskai BJ, Frosch MP.

Neurobiol Dis. 2006 Dec;24(3):516-24. Epub 2006 Oct 5.

PMID:
17029828
[PubMed - indexed for MEDLINE]
5.

Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice.

Laursen B, Mørk A, Plath N, Kristiansen U, Bastlund JF.

Behav Brain Res. 2013 Mar 1;240:146-52. doi: 10.1016/j.bbr.2012.11.012. Epub 2012 Nov 22.

PMID:
23178660
[PubMed - indexed for MEDLINE]
6.

Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein.

Lee KW, Lee SH, Kim H, Song JS, Yang SD, Paik SG, Han PL.

J Neurosci Res. 2004 May 15;76(4):572-80.

PMID:
15114629
[PubMed - indexed for MEDLINE]
7.

Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimer's disease mitigates Aβ pathology and improves cognitive function.

Kim TK, Han HE, Kim H, Lee JE, Choi D, Park WJ, Han PL.

Exp Mol Med. 2012 Dec 31;44(12):740-8. doi: 10.3858/emm.2012.44.12.082.

PMID:
23172351
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A modified preparation (LMK03) of the oriental medicine Jangwonhwan reduces Abeta(1-42) level in the brain of Tg-APPswe/PS1dE9 mouse model of Alzheimer disease.

Seo JS, Jung EY, Kim JH, Lyu YS, Han PL, Kang HW.

J Ethnopharmacol. 2010 Aug 9;130(3):578-85.

PMID:
20669372
[PubMed - indexed for MEDLINE]
9.

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R.

J Neurosci. 2006 Oct 4;26(40):10129-40.

PMID:
17021169
[PubMed - indexed for MEDLINE]
Free Article
10.

Cognitive Impairment in Transgenic Mouse Models of Amyloid Deposition.

Morgan D.

In: Levin ED, Buccafusco JJ, editors. Animal Models of Cognitive Impairment. Boca Raton (FL): CRC Press; 2006. Chapter 10.

PMID:
21204370
[PubMed]
Books & Documents
11.

Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model.

Katsouri L, Georgopoulos S.

PLoS One. 2011;6(7):e21880. doi: 10.1371/journal.pone.0021880. Epub 2011 Jul 6.

PMID:
21755005
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease.

Willuweit A, Velden J, Godemann R, Manook A, Jetzek F, Tintrup H, Kauselmann G, Zevnik B, Henriksen G, Drzezga A, Pohlner J, Schoor M, Kemp JA, von der Kammer H.

PLoS One. 2009 Nov 20;4(11):e7931. doi: 10.1371/journal.pone.0007931.

PMID:
19936202
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes.

Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K.

Nat Med. 1998 Jan;4(1):97-100.

PMID:
9427614
[PubMed - indexed for MEDLINE]
14.

APP/PS1 transgenic mice treated with aluminum: an update of Alzheimer's disease model.

Zhang QL, Jia L, Jiao X, Guo WL, Ji JW, Yang HL, Niu Q.

Int J Immunopathol Pharmacol. 2012 Jan-Mar;25(1):49-58.

PMID:
22507317
[PubMed - indexed for MEDLINE]
15.

BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer's disease: differential Aβ antibody labeling of early-onset axon terminal pathology.

Cai Y, Zhang XM, Macklin LN, Cai H, Luo XG, Oddo S, Laferla FM, Struble RG, Rose GM, Patrylo PR, Yan XX.

Neurotox Res. 2012 Feb;21(2):160-74. doi: 10.1007/s12640-011-9256-9. Epub 2011 Jul 2.

PMID:
21725719
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Oriental medicine Jangwonhwan reduces Abeta(1-42) level and beta-amyloid deposition in the brain of Tg-APPswe/PS1dE9 mouse model of Alzheimer disease.

Seo JS, Yun JH, Baek IS, Leem YH, Kang HW, Cho HK, Lyu YS, Son HJ, Han PL.

J Ethnopharmacol. 2010 Mar 2;128(1):206-12. doi: 10.1016/j.jep.2010.01.014. Epub 2010 Jan 14.

PMID:
20079417
[PubMed - indexed for MEDLINE]
17.

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models.

Webster SJ, Bachstetter AD, Nelson PT, Schmitt FA, Van Eldik LJ.

Front Genet. 2014 Apr 23;5:88. doi: 10.3389/fgene.2014.00088. eCollection 2014. Review.

PMID:
24795750
[PubMed]
Free PMC Article
18.

Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice.

Dewachter I, van Dorpe J, Spittaels K, Tesseur I, Van Den Haute C, Moechars D, Van Leuven F.

Exp Gerontol. 2000 Sep;35(6-7):831-41. Review.

PMID:
11053674
[PubMed - indexed for MEDLINE]
19.

Early memory deficits precede plaque deposition in APPswe/PS1dE9 mice: involvement of oxidative stress and cholinergic dysfunction.

Zhang W, Bai M, Xi Y, Hao J, Liu L, Mao N, Su C, Miao J, Li Z.

Free Radic Biol Med. 2012 Apr 15;52(8):1443-52. doi: 10.1016/j.freeradbiomed.2012.01.023. Epub 2012 Feb 2.

PMID:
22342520
[PubMed - indexed for MEDLINE]
20.

A modified preparation (LMK03) of the oriental medicine Jangwonhwan reduces Abeta(1-42) level in the brain of Tg-APPswe/PS1dE9 mouse model of Alzheimer disease.

Seo JS, Jung EY, Kim JH, Lyu YS, Han PL, Kang HW.

J Ethnopharmacol. 2010 Jun 1. [Epub ahead of print]

PMID:
20685330
[PubMed - as supplied by publisher]

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