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Items: 1 to 20 of 107

1.

Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.

Rodríguez-Piñeiro AM, Bergström JH, Ermund A, Gustafsson JK, Schütte A, Johansson ME, Hansson GC.

Am J Physiol Gastrointest Liver Physiol. 2013 Sep 1;305(5):G348-56. doi: 10.1152/ajpgi.00047.2013. Epub 2013 Jul 5.

2.

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.

Holmén Larsson JM, Thomsson KA, Rodríguez-Piñeiro AM, Karlsson H, Hansson GC.

Am J Physiol Gastrointest Liver Physiol. 2013 Sep 1;305(5):G357-63. doi: 10.1152/ajpgi.00048.2013. Epub 2013 Jul 5.

3.

Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches.

Ermund A, Schütte A, Johansson ME, Gustafsson JK, Hansson GC.

Am J Physiol Gastrointest Liver Physiol. 2013 Sep 1;305(5):G341-7. doi: 10.1152/ajpgi.00046.2013. Epub 2013 Jul 5.

4.

Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.

Johansson ME, Thomsson KA, Hansson GC.

J Proteome Res. 2009 Jul;8(7):3549-57. doi: 10.1021/pr9002504.

PMID:
19432394
5.

Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus.

Schütte A, Ermund A, Becker-Pauly C, Johansson ME, Rodriguez-Pineiro AM, Bäckhed F, Müller S, Lottaz D, Bond JS, Hansson GC.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12396-401. doi: 10.1073/pnas.1407597111. Epub 2014 Aug 11.

6.

Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human MUC2.

Thomsson KA, Holmén-Larsson JM, Angström J, Johansson ME, Xia L, Hansson GC.

Glycobiology. 2012 Aug;22(8):1128-39. doi: 10.1093/glycob/cws083. Epub 2012 May 11.

7.
8.

Fast renewal of the distal colonic mucus layers by the surface goblet cells as measured by in vivo labeling of mucin glycoproteins.

Johansson ME.

PLoS One. 2012;7(7):e41009. doi: 10.1371/journal.pone.0041009. Epub 2012 Jul 17.

9.

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria.

Johansson ME, Phillipson M, Petersson J, Velcich A, Holm L, Hansson GC.

Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15064-9. doi: 10.1073/pnas.0803124105. Epub 2008 Sep 19.

10.

Cystic fibrosis mice lacking Muc1 have reduced amounts of intestinal mucus.

Parmley RR, Gendler SJ.

J Clin Invest. 1998 Nov 15;102(10):1798-806.

11.

The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice.

Erickson NA, Nyström EE, Mundhenk L, Arike L, Glauben R, Heimesaat MM, Fischer A, Bereswill S, Birchenough GM, Gruber AD, Johansson ME.

PLoS One. 2015 Jul 10;10(7):e0131991. doi: 10.1371/journal.pone.0131991. eCollection 2015.

12.

γδ T-cell-deficient mice show alterations in mucin expression, glycosylation, and goblet cells but maintain an intact mucus layer.

Kober OI, Ahl D, Pin C, Holm L, Carding SR, Juge N.

Am J Physiol Gastrointest Liver Physiol. 2014 Apr 1;306(7):G582-93. doi: 10.1152/ajpgi.00218.2013. Epub 2014 Feb 6.

13.

Gastrointestinal expression and partial cDNA cloning of murine Muc2.

van Klinken BJ, Einerhand AW, Duits LA, Makkink MK, Tytgat KM, Renes IB, Verburg M, Büller HA, Dekker J.

Am J Physiol. 1999 Jan;276(1 Pt 1):G115-24.

15.

Intestinal metaplasia of human stomach displays distinct patterns of mucin (MUC1, MUC2, MUC5AC, and MUC6) expression.

Reis CA, David L, Correa P, Carneiro F, de Bolós C, Garcia E, Mandel U, Clausen H, Sobrinho-Simões M.

Cancer Res. 1999 Mar 1;59(5):1003-7.

16.

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.

Pelaseyed T, Bergström JH, Gustafsson JK, Ermund A, Birchenough GM, Schütte A, van der Post S, Svensson F, Rodríguez-Piñeiro AM, Nyström EE, Wising C, Johansson ME, Hansson GC.

Immunol Rev. 2014 Jul;260(1):8-20. doi: 10.1111/imr.12182. Review.

17.

Threonine metabolism in the intestine of mice: loss of mucin 2 induces the threonine catabolic pathway.

van der Sluis M, Schaart MW, de Koning BA, Schierbeek H, Velcich A, Renes IB, van Goudoever JB.

J Pediatr Gastroenterol Nutr. 2009 Jul;49(1):99-107. doi: 10.1097/MPG.0b013e3181a23dbe.

PMID:
19502996
18.

Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro.

Chorley BN, Crews AL, Li Y, Adler KB, Minnicozzi M, Martin LD.

Respir Res. 2006 Feb 25;7:35.

19.

[Expression and clinical significance of Mucin and E-cadherin in colorectal tumors].

Yu XW, Rong W, Xu FL, Xu GY, Sun YR, Feng MY.

Ai Zheng. 2007 Nov;26(11):1204-10. Chinese.

PMID:
17991319
20.

Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis.

Johansson ME, Gustafsson JK, Holmén-Larsson J, Jabbar KS, Xia L, Xu H, Ghishan FK, Carvalho FA, Gewirtz AT, Sjövall H, Hansson GC.

Gut. 2014 Feb;63(2):281-91. doi: 10.1136/gutjnl-2012-303207. Epub 2013 Feb 20.

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