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Results: 1 to 20 of 97

1.

Retinal iron homeostasis in health and disease.

Song D, Dunaief JL.

Front Aging Neurosci. 2013 Jun 28;5:24. doi: 10.3389/fnagi.2013.00024. Print 2013.

PMID:
23825457
[PubMed]
Free PMC Article
2.

Iron homeostasis and toxicity in retinal degeneration.

He X, Hahn P, Iacovelli J, Wong R, King C, Bhisitkul R, Massaro-Giordano M, Dunaief JL.

Prog Retin Eye Res. 2007 Nov;26(6):649-73. Epub 2007 Aug 11. Review.

PMID:
17921041
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture.

Dunaief JL.

Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4660-4.

PMID:
17065470
[PubMed - indexed for MEDLINE]
Free Article
4.

Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration.

Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Kautz L, Roth MP, Dunaief JL.

Am J Pathol. 2011 Jul;179(1):335-48. doi: 10.1016/j.ajpath.2011.03.033. Epub 2011 May 3.

PMID:
21703414
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Iron toxicity as a potential factor in AMD.

Wong RW, Richa DC, Hahn P, Green WR, Dunaief JL.

Retina. 2007 Oct;27(8):997-1003. Review.

PMID:
18040235
[PubMed - indexed for MEDLINE]
6.

Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD.

Hadziahmetovic M, Dentchev T, Song Y, Haddad N, He X, Hahn P, Pratico D, Wen R, Harris ZL, Lambris JD, Beard J, Dunaief JL.

Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2728-36. doi: 10.1167/iovs.07-1472. Epub 2008 Mar 7.

PMID:
18326691
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration.

Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Grieco S, Lee J, Lyubarsky A, Pratico D, Connelly J, Spino M, Harris ZL, Dunaief JL.

Invest Ophthalmol Vis Sci. 2011 Feb 16;52(2):959-68. doi: 10.1167/iovs.10-6207.

PMID:
21051716
[PubMed - indexed for MEDLINE]
Free Article
8.

Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activity.

Chen H, Lukas TJ, Du N, Suyeoka G, Neufeld AH.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1895-902. doi: 10.1167/iovs.08-2850. Epub 2009 Jan 17.

PMID:
19151392
[PubMed - indexed for MEDLINE]
Free Article
9.

Iron and age-related macular degeneration.

Błasiak J, Skłodowska A, Ulińska M, Szaflik JP.

Klin Oczna. 2009;111(4-6):174-7. Review.

PMID:
19673453
[PubMed - indexed for MEDLINE]
10.

Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).

Ramkumar HL, Zhang J, Chan CC.

Prog Retin Eye Res. 2010 May;29(3):169-90. doi: 10.1016/j.preteyeres.2010.02.002. Epub 2010 Mar 3. Review.

PMID:
20206286
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration.

Hahn P, Qian Y, Dentchev T, Chen L, Beard J, Harris ZL, Dunaief JL.

Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13850-5. Epub 2004 Sep 13.

PMID:
15365174
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium.

Wolkow N, Song D, Song Y, Chu S, Hadziahmetovic M, Lee JC, Iacovelli J, Grieco S, Dunaief JL.

Am J Pathol. 2012 Apr;180(4):1614-24. doi: 10.1016/j.ajpath.2011.12.041. Epub 2012 Feb 17.

PMID:
22342521
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina.

Hahn P, Dentchev T, Qian Y, Rouault T, Harris ZL, Dunaief JL.

Mol Vis. 2004 Aug 26;10:598-607.

PMID:
15354085
[PubMed - indexed for MEDLINE]
Free Article
14.

Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane.

Hahn P, Milam AH, Dunaief JL.

Arch Ophthalmol. 2003 Aug;121(8):1099-105.

PMID:
12912686
[PubMed - indexed for MEDLINE]
15.

The iron carrier transferrin is upregulated in retinas from patients with age-related macular degeneration.

Chowers I, Wong R, Dentchev T, Farkas RH, Iacovelli J, Gunatilaka TL, Medeiros NE, Presley JB, Campochiaro PA, Curcio CA, Dunaief JL, Zack DJ.

Invest Ophthalmol Vis Sci. 2006 May;47(5):2135-40.

PMID:
16639025
[PubMed - indexed for MEDLINE]
Free Article
16.

Macular degeneration in a patient with aceruloplasminemia, a disease associated with retinal iron overload.

Dunaief JL, Richa C, Franks EP, Schultze RL, Aleman TS, Schenck JF, Zimmerman EA, Brooks DG.

Ophthalmology. 2005 Jun;112(6):1062-5.

PMID:
15882908
[PubMed - indexed for MEDLINE]
17.

N-tert-butyl hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration.

Voloboueva LA, Killilea DW, Atamna H, Ames BN.

FASEB J. 2007 Dec;21(14):4077-86. Epub 2007 Jul 26.

PMID:
17656467
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD.

Ma W, Zhao L, Fontainhas AM, Fariss RN, Wong WT.

PLoS One. 2009 Nov 20;4(11):e7945. doi: 10.1371/journal.pone.0007945.

PMID:
19936204
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice.

Song D, Zhao L, Li Y, Hadziahmetovic M, Song Y, Connelly J, Spino M, Dunaief JL.

Invest Ophthalmol Vis Sci. 2014 Jun 26;55(7):4525-32. doi: 10.1167/iovs.14-14568.

PMID:
24970260
[PubMed - in process]
20.

Potential role of retinal pigment epithelial lipofuscin accumulation in age-related macular degeneration.

Katz ML.

Arch Gerontol Geriatr. 2002 May-Jun;34(3):359-70.

PMID:
14764336
[PubMed]

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