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Results: 1 to 20 of 94

1.

Effects of Calorie Restriction and IGF-1 Receptor Blockade on the Progression of 22Rv1 Prostate Cancer Xenografts.

Galet C, Gray A, Said JW, Castor B, Wan J, Beltran PJ, Calzone FJ, Elashoff D, Cohen P, Aronson WJ.

Int J Mol Sci. 2013 Jul 3;14(7):13782-95. doi: 10.3390/ijms140713782.

PMID:
23823800
[PubMed]
Free PMC Article
2.

Effect of a low-fat diet combined with IGF-1 receptor blockade on 22Rv1 prostate cancer xenografts.

Konijeti R, Koyama S, Gray A, Barnard RJ, Said JW, Castor B, Elashoff D, Wan J, Beltran PJ, Calzone FJ, Cohen P, Galet C, Aronson WJ.

Mol Cancer Ther. 2012 Jul;11(7):1539-46. doi: 10.1158/1535-7163.MCT-11-1003. Epub 2012 May 4.

PMID:
22562985
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Targeting IGF-IR with ganitumab inhibits tumorigenesis and increases durability of response to androgen-deprivation therapy in VCaP prostate cancer xenografts.

Fahrenholtz CD, Beltran PJ, Burnstein KL.

Mol Cancer Ther. 2013 Apr;12(4):394-404. doi: 10.1158/1535-7163.MCT-12-0648. Epub 2013 Jan 24.

PMID:
23348048
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1.

Nogueira LM, Lavigne JA, Chandramouli GV, Lui H, Barrett JC, Hursting SD.

Cancer Med. 2012 Oct;1(2):275-88. doi: 10.1002/cam4.23. Epub 2012 Aug 6.

PMID:
23342276
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Effect of intermittent fasting on prostate cancer tumor growth in a mouse model.

Thomas JA 2nd, Antonelli JA, Lloyd JC, Masko EM, Poulton SH, Phillips TE, Pollak M, Freedland SJ.

Prostate Cancer Prostatic Dis. 2010 Dec;13(4):350-5. doi: 10.1038/pcan.2010.24. Epub 2010 Aug 24.

PMID:
20733612
[PubMed - indexed for MEDLINE]
6.

Age-dependent loss of insulin-like growth factor-1 receptor immunoreactive cells in the supraoptic hypothalamus is reduced in calorically restricted mice.

Yaghmaie F, Saeed O, Garan SA, Voelker MA, Gouw AM, Freitag W, Sternberg H, Timiras PS.

Int J Dev Neurosci. 2006 Nov;24(7):431-6. Epub 2006 Oct 10.

PMID:
17034982
[PubMed - indexed for MEDLINE]
7.

Calorie restriction decreases murine and human pancreatic tumor cell growth, nuclear factor-κB activation, and inflammation-related gene expression in an insulin-like growth factor-1-dependent manner.

Harvey AE, Lashinger LM, Hays D, Harrison LM, Lewis K, Fischer SM, Hursting SD.

PLoS One. 2014 May 7;9(5):e94151. doi: 10.1371/journal.pone.0094151. eCollection 2014.

PMID:
24804677
[PubMed - in process]
Free PMC Article
8.

Combined Inhibition of IGF-1R/IR and Src family kinases enhances antitumor effects in prostate cancer by decreasing activated survival pathways.

Dayyani F, Parikh NU, Varkaris AS, Song JH, Moorthy S, Chatterji T, Maity SN, Wolfe AR, Carboni JM, Gottardis MM, Logothetis CJ, Gallick GE.

PLoS One. 2012;7(12):e51189. doi: 10.1371/journal.pone.0051189. Epub 2012 Dec 26.

PMID:
23300537
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice.

Shukla S, Mishra A, Fu P, MacLennan GT, Resnick MI, Gupta S.

FASEB J. 2005 Dec;19(14):2042-4. Epub 2005 Oct 17.

PMID:
16230333
[PubMed - indexed for MEDLINE]
Free Article
10.

Serum insulin-like growth factor-I and mammary tumor development in ad libitum-fed, chronic calorie-restricted, and intermittent calorie-restricted MMTV-TGF-alpha mice.

Rogozina OP, Bonorden MJ, Grande JP, Cleary MP.

Cancer Prev Res (Phila). 2009 Aug;2(8):712-9. doi: 10.1158/1940-6207.CAPR-09-0028. Epub 2009 Aug 3.

PMID:
19654106
[PubMed - indexed for MEDLINE]
11.

Decreased systemic IGF-1 in response to calorie restriction modulates murine tumor cell growth, nuclear factor-κB activation, and inflammation-related gene expression.

Harvey AE, Lashinger LM, Otto G, Nunez NP, Hursting SD.

Mol Carcinog. 2013 Dec;52(12):997-1006. doi: 10.1002/mc.21940. Epub 2012 Jul 6.

PMID:
22778026
[PubMed - indexed for MEDLINE]
12.

Efficacy of ganitumab (AMG 479), alone and in combination with rapamycin, in Ewing's and osteogenic sarcoma models.

Beltran PJ, Chung YA, Moody G, Mitchell P, Cajulis E, Vonderfecht S, Kendall R, Radinsky R, Calzone FJ.

J Pharmacol Exp Ther. 2011 Jun;337(3):644-54. doi: 10.1124/jpet.110.178400. Epub 2011 Mar 8.

PMID:
21385891
[PubMed - indexed for MEDLINE]
Free Article
13.

Ganitumab (AMG 479) inhibits IGF-II-dependent ovarian cancer growth and potentiates platinum-based chemotherapy.

Beltran PJ, Calzone FJ, Mitchell P, Chung YA, Cajulis E, Moody G, Belmontes B, Li CM, Vonderfecht S, Velculescu VE, Yang G, Qi J, Slamon DJ, Konecny GE.

Clin Cancer Res. 2014 Jun 1;20(11):2947-58. doi: 10.1158/1078-0432.CCR-13-3448. Epub 2014 Apr 11.

PMID:
24727326
[PubMed - in process]
Free PMC Article
14.

Genetic blockade of insulin-like growth factor-1 receptor via recombinant adenovirus in lung cancer can be enhanced by the histone deacetylase inhibitor, vorinostat.

Park MY, Kim DR, Eo EY, Lim HJ, Park JS, Cho YJ, Yoon HI, Lee JH, Lee CT.

J Gene Med. 2013 Mar-Apr;15(3-4):115-22. doi: 10.1002/jgm.2699.

PMID:
23413016
[PubMed - indexed for MEDLINE]
15.

A ketogenic diet increases brain insulin-like growth factor receptor and glucose transporter gene expression.

Cheng CM, Kelley B, Wang J, Strauss D, Eagles DA, Bondy CA.

Endocrinology. 2003 Jun;144(6):2676-82.

PMID:
12746332
[PubMed - indexed for MEDLINE]
16.

Antisense oligonucleotide targeting of insulin-like growth factor-1 receptor (IGF-1R) in prostate cancer.

Furukawa J, Wraight CJ, Freier SM, Peralta E, Atley LM, Monia BP, Gleave ME, Cox ME.

Prostate. 2010 Feb 1;70(2):206-18. doi: 10.1002/pros.21054.

PMID:
19790231
[PubMed - indexed for MEDLINE]
17.

Epitope-specific mechanisms of IGF1R inhibition by ganitumab.

Calzone FJ, Cajulis E, Chung YA, Tsai MM, Mitchell P, Lu J, Chen C, Sun J, Radinsky R, Kendall R, Beltran PJ.

PLoS One. 2013;8(2):e55135. doi: 10.1371/journal.pone.0055135. Epub 2013 Feb 1.

PMID:
23383308
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Luteolin inhibits insulin-like growth factor 1 receptor signaling in prostate cancer cells.

Fang J, Zhou Q, Shi XL, Jiang BH.

Carcinogenesis. 2007 Mar;28(3):713-23. Epub 2006 Oct 25.

PMID:
17065200
[PubMed - indexed for MEDLINE]
Free Article
19.

Blocking dopamine D2 receptors by haloperidol curtails the beneficial impact of calorie restriction on the metabolic phenotype of high-fat diet induced obese mice.

de Leeuw van Weenen JE, Auvinen HE, Parlevliet ET, Coomans CP, Schröder-van der Elst JP, Meijer OC, Pijl H.

J Neuroendocrinol. 2011 Feb;23(2):158-67. doi: 10.1111/j.1365-2826.2010.02092.x.

PMID:
21062378
[PubMed - indexed for MEDLINE]
20.

Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice.

Dunn SE, Kari FW, French J, Leininger JR, Travlos G, Wilson R, Barrett JC.

Cancer Res. 1997 Nov 1;57(21):4667-72.

PMID:
9354418
[PubMed - indexed for MEDLINE]
Free Article

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