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Items: 1 to 20 of 126

1.

PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum.

Jiang L, Mu J, Zhang Q, Ni T, Srinivasan P, Rayavara K, Yang W, Turner L, Lavstsen T, Theander TG, Peng W, Wei G, Jing Q, Wakabayashi Y, Bansal A, Luo Y, Ribeiro JM, Scherf A, Aravind L, Zhu J, Zhao K, Miller LH.

Nature. 2013 Jul 11;499(7457):223-7. doi: 10.1038/nature12361. Epub 2013 Jul 3.

2.

Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria.

Zhang Q, Siegel TN, Martins RM, Wang F, Cao J, Gao Q, Cheng X, Jiang L, Hon CC, Scheidig-Benatar C, Sakamoto H, Turner L, Jensen AT, Claes A, Guizetti J, Malmquist NA, Scherf A.

Nature. 2014 Sep 18;513(7518):431-5. doi: 10.1038/nature13468. Epub 2014 Jun 29.

PMID:
25043062
3.

A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria.

Voss TS, Healer J, Marty AJ, Duffy MF, Thompson JK, Beeson JG, Reeder JC, Crabb BS, Cowman AF.

Nature. 2006 Feb 23;439(7079):1004-8. Epub 2005 Dec 28.

PMID:
16382237
4.

Expression of P. falciparum var genes involves exchange of the histone variant H2A.Z at the promoter.

Petter M, Lee CC, Byrne TJ, Boysen KE, Volz J, Ralph SA, Cowman AF, Brown GV, Duffy MF.

PLoS Pathog. 2011 Feb;7(2):e1001292. doi: 10.1371/journal.ppat.1001292. Epub 2011 Feb 17.

5.

Active transcription is required for maintenance of epigenetic memory in the malaria parasite Plasmodium falciparum.

Dzikowski R, Deitsch KW.

J Mol Biol. 2008 Oct 3;382(2):288-97. doi: 10.1016/j.jmb.2008.07.015. Epub 2008 Jul 16.

6.

Chromatin associated sense and antisense noncoding RNAs are transcribed from the var gene family of virulence genes of the malaria parasite Plasmodium falciparum.

Epp C, Li F, Howitt CA, Chookajorn T, Deitsch KW.

RNA. 2009 Jan;15(1):116-27. doi: 10.1261/rna.1080109. Epub 2008 Nov 26.

7.

Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum.

Tonkin CJ, Carret CK, Duraisingh MT, Voss TS, Ralph SA, Hommel M, Duffy MF, Silva LM, Scherf A, Ivens A, Speed TP, Beeson JG, Cowman AF.

PLoS Biol. 2009 Apr 14;7(4):e84. doi: 10.1371/journal.pbio.1000084.

8.

Epigenetic memory at malaria virulence genes.

Chookajorn T, Dzikowski R, Frank M, Li F, Jiwani AZ, Hartl DL, Deitsch KW.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):899-902. Epub 2007 Jan 5.

9.
10.

5' flanking region of var genes nucleate histone modification patterns linked to phenotypic inheritance of virulence traits in malaria parasites.

Lopez-Rubio JJ, Gontijo AM, Nunes MC, Issar N, Hernandez Rivas R, Scherf A.

Mol Microbiol. 2007 Dec;66(6):1296-305. Epub 2007 Nov 19.

11.

Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1.

Joergensen L, Bengtsson DC, Bengtsson A, Ronander E, Berger SS, Turner L, Dalgaard MB, Cham GK, Victor ME, Lavstsen T, Theander TG, Arnot DE, Jensen AT.

PLoS Pathog. 2010 Sep 2;6(9):e1001083. doi: 10.1371/journal.ppat.1001083.

12.

Insulator-like pairing elements regulate silencing and mutually exclusive expression in the malaria parasite Plasmodium falciparum.

Avraham I, Schreier J, Dzikowski R.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):E3678-86. doi: 10.1073/pnas.1214572109. Epub 2012 Nov 29.

13.

Antigenic variation in Plasmodium falciparum.

Scherf A, Lopez-Rubio JJ, Riviere L.

Annu Rev Microbiol. 2008;62:445-70. doi: 10.1146/annurev.micro.61.080706.093134. Review.

PMID:
18785843
14.

Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes.

Jensen AT, Magistrado P, Sharp S, Joergensen L, Lavstsen T, Chiucchiuini A, Salanti A, Vestergaard LS, Lusingu JP, Hermsen R, Sauerwein R, Christensen J, Nielsen MA, Hviid L, Sutherland C, Staalsoe T, Theander TG.

J Exp Med. 2004 May 3;199(9):1179-90.

15.

Nuclear pores and perinuclear expression sites of var and ribosomal DNA genes correspond to physically distinct regions in Plasmodium falciparum.

Guizetti J, Martins RM, Guadagnini S, Claes A, Scherf A.

Eukaryot Cell. 2013 May;12(5):697-702. doi: 10.1128/EC.00023-13. Epub 2013 Mar 8.

16.

Strict pairing of var promoters and introns is required for var gene silencing in the malaria parasite Plasmodium falciparum.

Frank M, Dzikowski R, Costantini D, Amulic B, Berdougo E, Deitsch K.

J Biol Chem. 2006 Apr 14;281(15):9942-52. Epub 2006 Feb 2.

17.

Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors.

Flueck C, Bartfai R, Volz J, Niederwieser I, Salcedo-Amaya AM, Alako BT, Ehlgen F, Ralph SA, Cowman AF, Bozdech Z, Stunnenberg HG, Voss TS.

PLoS Pathog. 2009 Sep;5(9):e1000569. doi: 10.1371/journal.ppat.1000569. Epub 2009 Sep 4.

18.

The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer.

Wang CW, Hermsen CC, Sauerwein RW, Arnot DE, Theander TG, Lavstsen T.

Parasitol Int. 2009 Dec;58(4):478-80. doi: 10.1016/j.parint.2009.07.004. Epub 2009 Jul 16.

PMID:
19616120
19.

A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum.

Ukaegbu UE, Zhang X, Heinberg AR, Wele M, Chen Q, Deitsch KW.

PLoS Genet. 2015 May 19;11(5):e1005234. doi: 10.1371/journal.pgen.1005234. eCollection 2015 May.

20.

Regulation of antigenic variation in Plasmodium falciparum: censoring freedom of expression?

Duffy MF, Reeder JC, Brown GV.

Trends Parasitol. 2003 Mar;19(3):121-4.

PMID:
12643994
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