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Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition.

Lopez-Atalaya JP, Ito S, Valor LM, Benito E, Barco A.

Nucleic Acids Res. 2013 Sep;41(17):8072-84. doi: 10.1093/nar/gkt590. Epub 2013 Jul 1.


HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes.

Ooi JY, Tuano NK, Rafehi H, Gao XM, Ziemann M, Du XJ, El-Osta A.

Epigenetics. 2015;10(5):418-30. doi: 10.1080/15592294.2015.1024406. Epub 2015 May 5.


A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests.

Schroeder FA, Lewis MC, Fass DM, Wagner FF, Zhang YL, Hennig KM, Gale J, Zhao WN, Reis S, Barker DD, Berry-Scott E, Kim SW, Clore EL, Hooker JM, Holson EB, Haggarty SJ, Petryshen TL.

PLoS One. 2013 Aug 14;8(8):e71323. doi: 10.1371/journal.pone.0071323. eCollection 2013.


Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain.

Im H, Grass JA, Christensen HM, Perkins A, Bresnick EH.

Biochemistry. 2002 Dec 24;41(51):15152-60.


Trichostatin A selectively suppresses the cold-induced transcription of the ZmDREB1 gene in maize.

Hu Y, Zhang L, Zhao L, Li J, He S, Zhou K, Yang F, Huang M, Jiang L, Li L.

PLoS One. 2011;6(7):e22132. doi: 10.1371/journal.pone.0022132. Epub 2011 Jul 21.


Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain.

Grandjean V, O'Neill L, Sado T, Turner B, Ferguson-Smith A.

FEBS Lett. 2001 Jan 19;488(3):165-9.


Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A.

Gialitakis M, Kretsovali A, Spilianakis C, Kravariti L, Mages J, Hoffmann R, Hatzopoulos AK, Papamatheakis J.

Nucleic Acids Res. 2006 Feb 1;34(3):765-72. Print 2006.


Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells.

Huang Y, Vasilatos SN, Boric L, Shaw PG, Davidson NE.

Breast Cancer Res Treat. 2012 Feb;131(3):777-89. doi: 10.1007/s10549-011-1480-8. Epub 2011 Mar 31.


Vorinostat, a histone deacetylase inhibitor, facilitates fear extinction and enhances expression of the hippocampal NR2B-containing NMDA receptor gene.

Fujita Y, Morinobu S, Takei S, Fuchikami M, Matsumoto T, Yamamoto S, Yamawaki S.

J Psychiatr Res. 2012 May;46(5):635-43. doi: 10.1016/j.jpsychires.2012.01.026. Epub 2012 Feb 25.


Altered histone acetylation is associated with age-dependent memory impairment in mice.

Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Cota P, Wittnam JL, Gogol-Doering A, Opitz L, Salinas-Riester G, Dettenhofer M, Kang H, Farinelli L, Chen W, Fischer A.

Science. 2010 May 7;328(5979):753-6. doi: 10.1126/science.1186088. Erratum in: Science. 2010 Jun 25;328(5986):1634.


Vascular histone deacetylation by pharmacological HDAC inhibition.

Rafehi H, Balcerczyk A, Lunke S, Kaspi A, Ziemann M, Kn H, Okabe J, Khurana I, Ooi J, Khan AW, Du XJ, Chang L, Haviv I, Keating ST, Karagiannis TC, El-Osta A.

Genome Res. 2014 Aug;24(8):1271-84. doi: 10.1101/gr.168781.113. Epub 2014 Apr 14.


Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines.

Osada H, Tatematsu Y, Sugito N, Horio Y, Takahashi T.

Mol Carcinog. 2005 Dec;44(4):233-41.


Histone acetylation is not an accurate predictor of gene expression following treatment with histone deacetylase inhibitors.

Ellis DJ, Lawman ZK, Bonham K.

Biochem Biophys Res Commun. 2008 Mar 14;367(3):656-62. doi: 10.1016/j.bbrc.2007.12.157. Epub 2008 Jan 7.

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