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Results: 1 to 20 of 142

1.

HDAC dependent transcriptional repression of Bmp-7 potentiates TGF-β mediated renal fibrosis in obstructive uropathy.

Manson SR, Song JB, Hruska KA, Austin PF.

J Urol. 2014 Jan;191(1):242-52. doi: 10.1016/j.juro.2013.06.110. Epub 2013 Jun 29.

PMID:
23820056
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The BMP-7-Smad1/5/8 pathway promotes kidney repair after obstruction induced renal injury.

Manson SR, Niederhoff RA, Hruska KA, Austin PF.

J Urol. 2011 Jun;185(6 Suppl):2523-30. doi: 10.1016/j.juro.2011.01.034. Epub 2011 Apr 27.

PMID:
21527199
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Blocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signaling.

Liu N, He S, Ma L, Ponnusamy M, Tang J, Tolbert E, Bayliss G, Zhao TC, Yan H, Zhuang S.

PLoS One. 2013;8(1):e54001. doi: 10.1371/journal.pone.0054001. Epub 2013 Jan 16.

PMID:
23342059
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Endogenous BMP-7 is a critical molecular determinant of the reversibility of obstruction-induced renal injuries.

Manson SR, Niederhoff RA, Hruska KA, Austin PF.

Am J Physiol Renal Physiol. 2011 Dec;301(6):F1293-302. doi: 10.1152/ajprenal.00071.2011. Epub 2011 Aug 31.

PMID:
21880836
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling.

Park J, Lee SY, Ooshima A, Yang KM, Kang JM, Kim YW, Kim SJ.

J Mol Med (Berl). 2013 Nov;91(11):1273-84. doi: 10.1007/s00109-013-1086-1. Epub 2013 Sep 27.

PMID:
24072041
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Vitamin E ameliorates renal fibrosis in ureteral obstruction: role of maintaining BMP-7 during epithelial-to-mesenchymal transition.

Tasanarong A, Kongkham S, Thitiarchakul S, Eiam-Ong S.

J Med Assoc Thai. 2011 Dec;94 Suppl 7:S10-8.

PMID:
22619901
[PubMed - indexed for MEDLINE]
7.

Dimethylfumarate attenuates renal fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-β/Smad signaling.

Oh CJ, Kim JY, Choi YK, Kim HJ, Jeong JY, Bae KH, Park KG, Lee IK.

PLoS One. 2012;7(10):e45870. doi: 10.1371/journal.pone.0045870. Epub 2012 Oct 8.

PMID:
23056222
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy.

Pang M, Kothapally J, Mao H, Tolbert E, Ponnusamy M, Chin YE, Zhuang S.

Am J Physiol Renal Physiol. 2009 Oct;297(4):F996-F1005. doi: 10.1152/ajprenal.00282.2009. Epub 2009 Jul 29.

PMID:
19640900
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy.

Moon JA, Kim HT, Cho IS, Sheen YY, Kim DK.

Kidney Int. 2006 Oct;70(7):1234-43. Epub 2006 Aug 23.

PMID:
16929250
[PubMed - indexed for MEDLINE]
10.

Obstructive nephropathy and renal fibrosis: The role of bone morphogenic protein-7 and hepatocyte growth factor.

Klahr S, Morrissey J.

Kidney Int Suppl. 2003 Nov;(87):S105-12. Review.

PMID:
14531782
[PubMed - indexed for MEDLINE]
11.

C-reactive protein promotes acute renal inflammation and fibrosis in unilateral ureteral obstructive nephropathy in mice.

Li ZI, Chung AC, Zhou L, Huang XR, Liu F, Fu P, Fan JM, Szalai AJ, Lan HY.

Lab Invest. 2011 Jun;91(6):837-51. doi: 10.1038/labinvest.2011.42. Epub 2011 Mar 7.

PMID:
21383672
[PubMed - indexed for MEDLINE]
Free Article
12.

Defect in Runx2 gene accelerates ureteral obstruction-induced kidney fibrosis via increased TGF-β signaling pathway.

Kim JI, Jang HS, Jeong JH, Noh MR, Choi JY, Park KM.

Biochim Biophys Acta. 2013 Oct;1832(10):1520-7. doi: 10.1016/j.bbadis.2013.04.021. Epub 2013 Apr 29.

PMID:
23639629
[PubMed - indexed for MEDLINE]
13.

CD44v3-v10 reduces the profibrotic effects of TGF-β1 and attenuates tubular injury in the early stage of chronic obstructive nephropathy.

Rampanelli E, Rouschop K, Teske GJ, Claessen N, Leemans JC, Florquin S.

Am J Physiol Renal Physiol. 2013 Nov 15;305(10):F1445-54. doi: 10.1152/ajprenal.00340.2013. Epub 2013 Sep 11.

PMID:
24026183
[PubMed - indexed for MEDLINE]
14.

Protective effects of low-dose carbon monoxide against renal fibrosis induced by unilateral ureteral obstruction.

Wang L, Lee JY, Kwak JH, He Y, Kim SI, Choi ME.

Am J Physiol Renal Physiol. 2008 Mar;294(3):F508-17. Epub 2007 Dec 19.

PMID:
18094035
[PubMed - indexed for MEDLINE]
Free Article
15.

Bone morphogenetic protein-2 antagonizes renal interstitial fibrosis by promoting catabolism of type I transforming growth factor-beta receptors.

Yang YL, Liu YS, Chuang LY, Guh JY, Lee TC, Liao TN, Hung MY, Chiang TA.

Endocrinology. 2009 Feb;150(2):727-40. doi: 10.1210/en.2008-0090. Epub 2008 Oct 1.

PMID:
18832104
[PubMed - indexed for MEDLINE]
16.

Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction.

Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A.

J Clin Invest. 2003 Nov;112(10):1486-94.

PMID:
14617750
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Transforming growth factor-beta-dependent and -independent pathways of induction of tubulointerstitial fibrosis in beta6(-/-) mice.

Ma LJ, Yang H, Gaspert A, Carlesso G, Barty MM, Davidson JM, Sheppard D, Fogo AB.

Am J Pathol. 2003 Oct;163(4):1261-73.

PMID:
14507636
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Vitamin E ameliorates renal fibrosis by inhibition of TGF-beta/Smad2/3 signaling pathway in UUO mice.

Tasanarong A, Kongkham S, Duangchana S, Thitiarchakul S, Eiam-Ong S.

J Med Assoc Thai. 2011 Dec;94 Suppl 7:S1-9.

PMID:
22619900
[PubMed - indexed for MEDLINE]
19.

Role of connective tissue growth factor in profibrotic action of transforming growth factor-beta: a potential target for preventing renal fibrosis.

Yokoi H, Sugawara A, Mukoyama M, Mori K, Makino H, Suganami T, Nagae T, Yahata K, Fujinaga Y, Tanaka I, Nakao K.

Am J Kidney Dis. 2001 Oct;38(4 Suppl 1):S134-8.

PMID:
11576939
[PubMed - indexed for MEDLINE]
20.

Angiotensin II receptor antagonist ameliorates renal tubulointerstitial fibrosis caused by unilateral ureteral obstruction.

Ishidoya S, Morrissey J, McCracken R, Reyes A, Klahr S.

Kidney Int. 1995 May;47(5):1285-94.

PMID:
7637258
[PubMed - indexed for MEDLINE]

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