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Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation.

Marras F, Nicco E, Bozzano F, Di Biagio A, Dentone C, Pontali E, Boni S, Setti M, Orofino G, Mantia E, Bartolacci V, Bisio F, Riva A, Biassoni R, Moretta L, De Maria A.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11970-5. doi: 10.1073/pnas.1302090110. Epub 2013 Jul 1.


Specific phenotypic and functional features of natural killer cells from HIV-infected long-term nonprogressors and HIV controllers.

Vieillard V, Fausther-Bovendo H, Samri A, Debré P; French Asymptomatiques à Long Terme (ALT) ANRS-CO15 Study Group.

J Acquir Immune Defic Syndr. 2010 Apr;53(5):564-73. doi: 10.1097/QAI.0b013e3181d0c5b4.


Influence of in vitro IL-2 or IL-15 alone or in combination with Hsp-70-derived 14-mer peptide (TKD) on the expression of NK cell activatory and inhibitory receptors.

Hromadnikova I, Pirkova P, Sedlackova L.

Mediators Inflamm. 2013;2013:405295. doi: 10.1155/2013/405295. Epub 2013 Feb 17.


Expressions of natural cytotoxicity receptors and NKG2D on decidual natural killer cells in patients having spontaneous abortions.

Zhang Y, Zhao A, Wang X, Shi G, Jin H, Lin Q.

Fertil Steril. 2008 Nov;90(5):1931-7. Epub 2007 Nov 26.


The impaired NK cell cytolytic function in viremic HIV-1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44).

De Maria A, Fogli M, Costa P, Murdaca G, Puppo F, Mavilio D, Moretta A, Moretta L.

Eur J Immunol. 2003 Sep;33(9):2410-8.


Activated gammadelta T cells express the natural cytotoxicity receptor natural killer p 44 and show cytotoxic activity against myeloma cells.

von Lilienfeld-Toal M, Nattermann J, Feldmann G, Sievers E, Frank S, Strehl J, Schmidt-Wolf IG.

Clin Exp Immunol. 2006 Jun;144(3):528-33.


Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.

Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.

Gastroenterology. 2010 Sep;139(3):882-92, 892.e1-3. doi: 10.1053/j.gastro.2010.05.040. Epub 2010 Jun 1.


Activation of natural killer cells by hepatitis C virus particles in vitro.

Farag MM, Weigand K, Encke J, Momburg F.

Clin Exp Immunol. 2011 Sep;165(3):352-62. doi: 10.1111/j.1365-2249.2011.04431.x. Epub 2011 Jun 17.


Human NK cytotoxicity against porcine cells is triggered by NKp44 and NKG2D.

Forte P, Lilienfeld BG, Baumann BC, Seebach JD.

J Immunol. 2005 Oct 15;175(8):5463-70.


Successfully treated HIV-infected patients have differential expression of NK cell receptors (NKp46 and NKp30) according to AIDS status at presentation.

Bisio F, Bozzano F, Marras F, Di Biagio A, Moretta L, De Maria A.

Immunol Lett. 2013 Apr;152(1):16-24. doi: 10.1016/j.imlet.2013.03.003. Epub 2013 Mar 26.


NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis.

Vitale M, Bottino C, Sivori S, Sanseverino L, Castriconi R, Marcenaro E, Augugliaro R, Moretta L, Moretta A.

J Exp Med. 1998 Jun 15;187(12):2065-72.


Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions.

Garcia-Iglesias T, Del Toro-Arreola A, Albarran-Somoza B, Del Toro-Arreola S, Sanchez-Hernandez PE, Ramirez-Dueñas MG, Balderas-Peña LM, Bravo-Cuellar A, Ortiz-Lazareno PC, Daneri-Navarro A.

BMC Cancer. 2009 Jun 16;9:186. doi: 10.1186/1471-2407-9-186.


Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

Nielsen N, Pascal V, Fasth AE, Sundström Y, Galsgaard ED, Ahern D, Andersen M, Baslund B, Bartels EM, Bliddal H, Feldmann M, Malmström V, Berg L, Spee P, Söderström K.

Immunology. 2014 Aug;142(4):581-93. doi: 10.1111/imm.12271.


Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2- versus IL-15-activated NK cells.

Chiossone L, Vitale C, Cottalasso F, Moretti S, Azzarone B, Moretta L, Mingari MC.

Blood. 2007 May 1;109(9):3767-75. Epub 2007 Jan 18.


NK cytotoxicity against CD4+ T cells during HIV-1 infection: a gp41 peptide induces the expression of an NKp44 ligand.

Vieillard V, Strominger JL, Debré P.

Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10981-6. Epub 2005 Jul 26.


Surface expression and cytolytic function of natural killer cell receptors is altered in chronic hepatitis C.

Nattermann J, Feldmann G, Ahlenstiel G, Langhans B, Sauerbruch T, Spengler U.

Gut. 2006 Jun;55(6):869-77. Epub 2005 Dec 1.


Dual-functional capability of CD3+CD56+ CIK cells, a T-cell subset that acquires NK function and retains TCR-mediated specific cytotoxicity.

Pievani A, Borleri G, Pende D, Moretta L, Rambaldi A, Golay J, Introna M.

Blood. 2011 Sep 22;118(12):3301-10. doi: 10.1182/blood-2011-02-336321. Epub 2011 Aug 5.


Regulatory role of NKp44, NKp46, DNAM-1 and NKG2D receptors in the interaction between NK cells and trophoblast cells. Evidence for divergent functional profiles of decidual versus peripheral NK cells.

Vacca P, Cantoni C, Prato C, Fulcheri E, Moretta A, Moretta L, Mingari MC.

Int Immunol. 2008 Nov;20(11):1395-405. doi: 10.1093/intimm/dxn105. Epub 2008 Sep 23.


Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells.

Ferlazzo G, Tsang ML, Moretta L, Melioli G, Steinman RM, Münz C.

J Exp Med. 2002 Feb 4;195(3):343-51.

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