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Items: 1 to 20 of 208

1.

Simultaneous quantitative analyses of indole and oxindole alkaloids of Uncaria Hook in rat plasma and brain after oral administration of the traditional Japanese medicine Yokukansan using high-performance liquid chromatography with tandem mass spectrometry.

Kushida H, Fukutake M, Tabuchi M, Katsuhara T, Nishimura H, Ikarashi Y, Kanitani M, Kase Y.

Biomed Chromatogr. 2013 Dec;27(12):1647-56. doi: 10.1002/bmc.2974. Epub 2013 Jul 1.

PMID:
23813572
2.

The blood-brain barrier permeability of geissoschizine methyl ether in Uncaria hook, a galenical constituent of the traditional Japanese medicine yokukansan.

Imamura S, Tabuchi M, Kushida H, Nishi A, Kanno H, Yamaguchi T, Sekiguchi K, Ikarashi Y, Kase Y.

Cell Mol Neurobiol. 2011 Jul;31(5):787-93. doi: 10.1007/s10571-011-9676-3. Epub 2011 Mar 26.

PMID:
21442303
3.

Determination of rhynchophylline and hirsutine in rat plasma by UPLC-MS/MS after oral administration of Uncaria rhynchophylla extract.

Wu YT, Lin LC, Tsai TH.

Biomed Chromatogr. 2014 Mar;28(3):439-45. doi: 10.1002/bmc.3052. Epub 2013 Oct 9.

PMID:
24122787
4.

Effects of geissoschizine methyl ether, an indole alkaloid in Uncaria hook, a constituent of yokukansan, on human recombinant serotonin 7 receptor.

Ueki T, Nishi A, Imamura S, Kanno H, Mizoguchi K, Sekiguchi K, Ikarashi Y, Kase Y.

Cell Mol Neurobiol. 2013 Jan;33(1):129-35. doi: 10.1007/s10571-012-9878-3. Epub 2012 Sep 12.

PMID:
22968712
5.

Metabolic profiling of the Uncaria hook alkaloid geissoschizine methyl ether in rat and human liver microsomes using high-performance liquid chromatography with tandem mass spectrometry.

Kushida H, Matsumoto T, Igarashi Y, Nishimura H, Watanabe J, Maemura K, Kase Y.

Molecules. 2015 Jan 27;20(2):2100-14. doi: 10.3390/molecules20022100.

6.

Simultaneous determination of ten alkaloids of crude and wine-processed Rhizoma Coptidis aqueous extracts in rat plasma by UHPLC-ESI-MS/MS and its application to a comparative pharmacokinetic study.

Qian XC, Zhang L, Tao Y, Huang P, Li JS, Chai C, Li W, Di LQ, Cai BC.

J Pharm Biomed Anal. 2015 Feb;105:64-73. doi: 10.1016/j.jpba.2014.11.049. Epub 2014 Dec 5.

PMID:
25543284
7.

UHPLC-ESI-MS/MS determination and pharmacokinetic study of two alkaloid components in rat plasma after oral administration of the extract of Corydalis bungeana Turcz.

Yang C, Xiao Y, Wang Z, Wang S, Chen L, Wu L, Liu G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 1;960:59-66. doi: 10.1016/j.jchromb.2014.04.009. Epub 2014 Apr 18.

PMID:
24786221
8.

Geissoschizine methyl ether, an alkaloid in Uncaria hook, is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan.

Nishi A, Yamaguchi T, Sekiguchi K, Imamura S, Tabuchi M, Kanno H, Nakai Y, Hashimoto K, Ikarashi Y, Kase Y.

Neuroscience. 2012 Apr 5;207:124-36. doi: 10.1016/j.neuroscience.2012.01.037. Epub 2012 Jan 24.

PMID:
22314317
9.
10.

Geissoschizine methyl ether, a corynanthean-type indole alkaloid from Uncaria rhynchophylla as a potential acetylcholinesterase inhibitor.

Yang ZD, Duan DZ, Du J, Yang MJ, Li S, Yao XJ.

Nat Prod Res. 2012;26(1):22-8. doi: 10.1080/14786419.2010.529811. Epub 2011 Jun 30.

PMID:
21714741
11.

Simultaneous determination of ten active constituents of Yankening Capsule in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry.

Wang J, Pang Q, Cen W, Zhu P, Xu Y.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jan 26;978-979:43-53. doi: 10.1016/j.jchromb.2014.10.016. Epub 2014 Oct 22.

PMID:
25531869
12.

Simultaneous determination of active xanthone glycosides, timosaponins and alkaloids in rat plasma after oral administration of Zi-Shen Pill extract for the pharmacokinetic study by liquid chromatography-tandem mass spectrometry.

Cai F, Xu W, Wei H, Sun L, Gao S, Yang Q, Feng J, Zhang F, Chen W.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Jul 1;878(21):1845-54. doi: 10.1016/j.jchromb.2010.05.024. Epub 2010 May 24.

PMID:
20541984
14.

Development of LC-MS determination method and back-propagation ANN pharmacokinetic model of corynoxeine in rat.

Ma J, Cai J, Lin G, Chen H, Wang X, Wang X, Hu L.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 May 15;959:10-5. doi: 10.1016/j.jchromb.2014.03.024. Epub 2014 Mar 31.

PMID:
24732215
15.
17.

Simultaneous quantification of three active alkaloids from a traditional Chinese medicine Ramulus Mori (Sangzhi) in rat plasma using liquid chromatography-tandem mass spectrometry.

Yang S, Wang B, Xia X, Li X, Wang R, Sheng L, Li D, Liu Y, Li Y.

J Pharm Biomed Anal. 2015 May 10;109:177-83. doi: 10.1016/j.jpba.2015.02.019. Epub 2015 Feb 19.

PMID:
25778928
18.

Specific binding and characteristics of geissoschizine methyl ether, an indole alkaloid of Uncaria Hook, in the rat brain.

Mizoguchi K, Kushida H, Kanno H, Igarashi Y, Nishimura H, Ikarashi Y, Kase Y.

J Ethnopharmacol. 2014 Dec 2;158 Pt A:264-70. doi: 10.1016/j.jep.2014.10.015. Epub 2014 Oct 31.

PMID:
25456433
19.

A HPLC-MS/MS method for the simultaneous quantitation of six alkaloids of Rhizoma Corydalis Decumbentis in rat plasma and its application to a pharmacokinetic study.

Liao C, Chang S, Yin S, Wang Z, Meng Y.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jan 1;944:101-6. doi: 10.1016/j.jchromb.2013.11.010. Epub 2013 Nov 15.

PMID:
24295909
20.
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