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Items: 1 to 20 of 168

1.

CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts.

Guo J, Zhou YJ, Hillwig ML, Shen Y, Yang L, Wang Y, Zhang X, Liu W, Peters RJ, Chen X, Zhao ZK, Huang L.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12108-13. doi: 10.1073/pnas.1218061110. Epub 2013 Jun 28.

2.

[Construction of Saccharomyces cerevisiae whole-cell biocatalyst system for conversion miltiradiene].

Cai Y, Guo J, Zhou YJ, Zhu ZW, Wu WY, Huang LQ, Chen M, Zhao ZB.

Yao Xue Xue Bao. 2013 Oct;48(10):1618-23. Chinese.

PMID:
24417091
3.

Candidate genes involved in tanshinone biosynthesis in hairy roots of Salvia miltiorrhiza revealed by cDNA microarray.

Cui G, Huang L, Tang X, Zhao J.

Mol Biol Rep. 2011 Apr;38(4):2471-8. doi: 10.1007/s11033-010-0383-9. Epub 2010 Nov 17.

PMID:
21082262
4.

Modular pathway engineering of diterpenoid synthases and the mevalonic acid pathway for miltiradiene production.

Zhou YJ, Gao W, Rong Q, Jin G, Chu H, Liu W, Yang W, Zhu Z, Li G, Zhu G, Huang L, Zhao ZK.

J Am Chem Soc. 2012 Feb 15;134(6):3234-41. doi: 10.1021/ja2114486. Epub 2012 Feb 6.

PMID:
22280121
5.

Transcriptome analysis of medicinal plant Salvia miltiorrhiza and identification of genes related to tanshinone biosynthesis.

Yang L, Ding G, Lin H, Cheng H, Kong Y, Wei Y, Fang X, Liu R, Wang L, Chen X, Yang C.

PLoS One. 2013 Nov 19;8(11):e80464. doi: 10.1371/journal.pone.0080464. eCollection 2013.

6.

Production of miltiradiene by metabolically engineered Saccharomyces cerevisiae.

Dai Z, Liu Y, Huang L, Zhang X.

Biotechnol Bioeng. 2012 Nov;109(11):2845-53. doi: 10.1002/bit.24547. Epub 2012 May 17.

PMID:
22566191
7.

RNA interference targeting CYP76AH1 in hairy roots of Salvia miltiorrhiza reveals its key role in the biosynthetic pathway of tanshinones.

Ma Y, Ma XH, Meng FY, Zhan ZL, Guo J, Huang LQ.

Biochem Biophys Res Commun. 2016 Jun 9. pii: S0006-291X(16)30954-8. doi: 10.1016/j.bbrc.2016.06.036. [Epub ahead of print]

PMID:
27291148
8.

[RNA interference and its effect of CYP76AH1 in biosynthesis of tanshinone].

Ma Y, Ma XH, Ma XJ, Guo J, Huang LQ.

Zhongguo Zhong Yao Za Zhi. 2015 Apr;40(8):1439-43. Chinese.

PMID:
26281576
9.

Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza.

Gao W, Sun HX, Xiao H, Cui G, Hillwig ML, Jackson A, Wang X, Shen Y, Zhao N, Zhang L, Wang XJ, Peters RJ, Huang L.

BMC Genomics. 2014 Jan 28;15:73. doi: 10.1186/1471-2164-15-73.

10.

Effects of combined elicitors on tanshinone metabolic profiling and SmCPS expression in Salvia miltiorrhiza hairy root cultures.

Cheng Q, He Y, Li G, Liu Y, Gao W, Huang L.

Molecules. 2013 Jun 27;18(7):7473-85. doi: 10.3390/molecules18077473.

11.

Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones.

Guo J, Ma X, Cai Y, Ma Y, Zhan Z, Zhou YJ, Liu W, Guan M, Yang J, Cui G, Kang L, Yang L, Shen Y, Tang J, Lin H, Ma X, Jin B, Liu Z, Peters RJ, Zhao ZK, Huang L.

New Phytol. 2016 Apr;210(2):525-34. doi: 10.1111/nph.13790. Epub 2015 Dec 18.

PMID:
26682704
12.

A functional genomics approach to tanshinone biosynthesis provides stereochemical insights.

Gao W, Hillwig ML, Huang L, Cui G, Wang X, Kong J, Yang B, Peters RJ.

Org Lett. 2009 Nov 19;11(22):5170-3. doi: 10.1021/ol902051v.

13.

Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots.

Yang D, Du X, Liang X, Han R, Liang Z, Liu Y, Liu F, Zhao J.

PLoS One. 2012;7(11):e46797. doi: 10.1371/journal.pone.0046797. Epub 2012 Nov 29.

14.

Cloning, molecular characterization and functional analysis of 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate reductase (HDR) gene for diterpenoid tanshinone biosynthesis in Salvia miltiorrhiza Bge. f. alba.

Hao G, Shi R, Tao R, Fang Q, Jiang X, Ji H, Feng L, Huang L.

Plant Physiol Biochem. 2013 Sep;70:21-32. doi: 10.1016/j.plaphy.2013.05.010. Epub 2013 May 22.

PMID:
23770591
15.

The Biosynthetic Pathways of Tanshinones and Phenolic Acids in Salvia miltiorrhiza.

Ma XH, Ma Y, Tang JF, He YL, Liu YC, Ma XJ, Shen Y, Cui GH, Lin HX, Rong QX, Guo J, Huang LQ.

Molecules. 2015 Sep 8;20(9):16235-54. doi: 10.3390/molecules200916235. Review.

16.

Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza.

Ma Y, Yuan L, Wu B, Li X, Chen S, Lu S.

J Exp Bot. 2012 Apr;63(7):2809-23. doi: 10.1093/jxb/err466. Epub 2012 Jan 30.

17.

[Cloning and induced expression analysis of 4-hydroxy-3-methyl-but-2-enyl diphosphate reductase gene (smHDR) of Salvia miltiorrhiza].

Cheng QQ, He YF, Li G, Jiang C, Yuan Y, Gao W, Huang LQ.

Yao Xue Xue Bao. 2013 Feb;48(2):236-42. Chinese.

PMID:
23672020
18.

Metabolic profiles and cDNA-AFLP analysis of Salvia miltiorrhiza and Salvia castanea Diel f. tomentosa Stib.

Yang D, Ma P, Liang X, Liang Z, Zhang M, Shen S, Liu H, Liu Y.

PLoS One. 2012;7(1):e29678. doi: 10.1371/journal.pone.0029678. Epub 2012 Jan 30.

19.

New abietane norditerpenoid from Salvia miltiorrhiza with cytotoxic activities.

Yao F, Zhang DW, Qu GW, Li GS, Dai SJ.

J Asian Nat Prod Res. 2012;14(9):913-7. doi: 10.1080/10286020.2012.699962. Epub 2012 Aug 28.

PMID:
22924543
20.

[Transcriptome characterization for Salvia miltiorrhiza using 454 GS FLX].

Li Y, Sun C, Luo HM, Li XW, Niu YY, Chen SL.

Yao Xue Xue Bao. 2010 Apr;45(4):524-9. Chinese.

PMID:
21355222
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