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Related Citations for PubMed (Select 23808395)


Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079.

Jimenez-Pacheco A, Mesuret G, Sanz-Rodriguez A, Tanaka K, Mooney C, Conroy R, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC, Engel T.

Epilepsia. 2013 Sep;54(9):1551-61. doi: 10.1111/epi.12257. Epub 2013 Jun 28.


Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice.

Engel T, Gomez-Villafuertes R, Tanaka K, Mesuret G, Sanz-Rodriguez A, Garcia-Huerta P, Miras-Portugal MT, Henshall DC, Diaz-Hernandez M.

FASEB J. 2012 Apr;26(4):1616-28. doi: 10.1096/fj.11-196089. Epub 2011 Dec 23.


P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage.

Mesuret G, Engel T, Hessel EV, Sanz-Rodriguez A, Jimenez-Pacheco A, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC.

CNS Neurosci Ther. 2014 Jun;20(6):556-64. doi: 10.1111/cns.12272. Epub 2014 Apr 21.


Hippocampal damage after intra-amygdala kainic acid-induced status epilepticus and seizure preconditioning-mediated neuroprotection in SJL mice.

Tanaka K, Jimenez-Mateos EM, Matsushima S, Taki W, Henshall DC.

Epilepsy Res. 2010 Feb;88(2-3):151-61. doi: 10.1016/j.eplepsyres.2009.10.012.


Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus.

Murphy BM, Engel T, Paucard A, Hatazaki S, Mouri G, Tanaka K, Tuffy LP, Jimenez-Mateos EM, Woods I, Dunleavy M, Bonner HP, Meller R, Simon RP, Strasser A, Prehn JH, Henshall DC.

Cell Death Differ. 2010 Mar;17(3):459-68. doi: 10.1038/cdd.2009.134. Epub 2009 Sep 25.


Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus.

Nicoletti JN, Shah SK, McCloskey DP, Goodman JH, Elkady A, Atassi H, Hylton D, Rudge JS, Scharfman HE, Croll SD.

Neuroscience. 2008 Jan 2;151(1):232-41. Epub 2007 Oct 26.


Neuroprotective effects of estrogens on hippocampal cells in adult female rats after status epilepticus.

Velísková J, Velísek L, Galanopoulou AS, Sperber EF.

Epilepsia. 2000;41 Suppl 6:S30-5.


P2X7 purinoceptors contribute to the death of Schwann cells transplanted into the spinal cord.

Luo J, Lee S, Wu D, Yeh J, Ellamushi H, Wheeler AP, Warnes G, Zhang Y, Bo X.

Cell Death Dis. 2013 Oct 3;4:e829. doi: 10.1038/cddis.2013.343.


P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control.

Engel T, Jimenez-Pacheco A, Miras-Portugal MT, Diaz-Hernandez M, Henshall DC.

Int J Physiol Pathophysiol Pharmacol. 2012;4(4):174-87. Epub 2012 Dec 26.


Delayed sclerosis, neuroprotection, and limbic epileptogenesis after status epilepticus in the rat.

Ebert U, Brandt C, Löscher W.

Epilepsia. 2002;43 Suppl 5:86-95.


Bi-lateral changes to hippocampal cholesterol levels during epileptogenesis and in chronic epilepsy following focal-onset status epilepticus in mice.

Heverin M, Engel T, Meaney S, Jimenez-Mateos EM, Al-Saudi R, Henshall DC.

Brain Res. 2012 Oct 22;1480:81-90. doi: 10.1016/j.brainres.2012.08.018. Epub 2012 Aug 17.


Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death.

Moran C, Sanz-Rodriguez A, Jimenez-Pacheco A, Martinez-Villareal J, McKiernan RC, Jimenez-Mateos EM, Mooney C, Woods I, Prehn JH, Henshall DC, Engel T.

Cell Death Dis. 2013 Apr 25;4:e606. doi: 10.1038/cddis.2013.136.


The P2X7 receptor-pannexin-1 complex decreases muscarinic acetylcholine receptor-mediated seizure susceptibility in mice.

Kim JE, Kang TC.

J Clin Invest. 2011 May;121(5):2037-47. doi: 10.1172/JCI44818. Epub 2011 Apr 18.


P2X receptors as targets for the treatment of status epilepticus.

Henshall DC, Diaz-Hernandez M, Miras-Portugal MT, Engel T.

Front Cell Neurosci. 2013 Nov 26;7:237. doi: 10.3389/fncel.2013.00237. Review.


The effect of P2X7 receptor activation on nuclear factor-κB phosphorylation induced by status epilepticus in the rat hippocampus.

Kim JE, Kim DS, Jin Ryu H, Il Kim W, Kim MJ, Won Kim D, Young Choi S, Kang TC.

Hippocampus. 2013 Jun;23(6):500-14. doi: 10.1002/hipo.22109. Epub 2013 Apr 5.


MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus.

Hu K, Xie YY, Zhang C, Ouyang DS, Long HY, Sun DN, Long LL, Feng L, Li Y, Xiao B.

BMC Neurosci. 2012 Sep 22;13:115. doi: 10.1186/1471-2202-13-115.


Effect of the calcineurin inhibitor FK506 on K+-Cl- cotransporter 2 expression in the mouse hippocampus after kainic acid-induced status epilepticus.

Shin HJ, Jeon BT, Kim J, Jeong EA, Kim MJ, Lee DH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS.

J Neural Transm. 2012 Jun;119(6):669-77. doi: 10.1007/s00702-011-0746-y. Epub 2011 Dec 11.

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