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Items: 1 to 20 of 106

1.

Probenecid potentiates MPTP/MPP+ toxicity by interference with cellular energy metabolism.

Alvarez-Fischer D, Noelker C, Grünewald A, Vulinović F, Guerreiro S, Fuchs J, Lu L, Lombès A, Hirsch EC, Oertel WH, Michel PP, Hartmann A.

J Neurochem. 2013 Dec;127(6):782-92. doi: 10.1111/jnc.12343. Epub 2013 Jul 8.

3.

Preferential Extracellular Generation of the Active Parkinsonian Toxin MPP+ by Transporter-Independent Export of the Intermediate MPDP+.

Schildknecht S, Pape R, Meiser J, Karreman C, Strittmatter T, Odermatt M, Cirri E, Friemel A, Ringwald M, Pasquarelli N, Ferger B, Brunner T, Marx A, Möller HM, Hiller K, Leist M.

Antioxid Redox Signal. 2015 Nov 1;23(13):1001-16. doi: 10.1089/ars.2015.6297.

6.

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity.

Przedborski S, Kostic V, Jackson-Lewis V, Naini AB, Simonetti S, Fahn S, Carlson E, Epstein CJ, Cadet JL.

J Neurosci. 1992 May;12(5):1658-67.

7.

The TrkB-positive dopaminergic neurons are less sensitive to MPTP insult in the substantia nigra of adult C57/BL mice.

Ding YX, Xia Y, Jiao XY, Duan L, Yu J, Wang X, Chen LW.

Neurochem Res. 2011 Oct;36(10):1759-66. doi: 10.1007/s11064-011-0491-5. Epub 2011 May 12.

PMID:
21562748
8.

The protective effect of riluzole in the MPTP model of Parkinson's disease in mice is not due to a decrease in MPP(+) accumulation.

Boireau A, Dubedat P, Bordier F, Imperato A, Moussaoui S.

Neuropharmacology. 2000 Apr 3;39(6):1016-20.

PMID:
10727711
9.

Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment.

Petroske E, Meredith GE, Callen S, Totterdell S, Lau YS.

Neuroscience. 2001;106(3):589-601.

PMID:
11591459
10.

Acetaldehyde directly enhances MPP+ neurotoxicity and delays its elimination from the striatum.

Zuddas A, Corsini GU, Schinelli S, Barker JL, Kopin IJ, di Porzio U.

Brain Res. 1989 Oct 30;501(1):11-22.

PMID:
2804689
11.

Synthetic bovine proline-rich-polypeptides generate hydroxyl radicals and fail to protect dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity in mice.

Knaryan VH, Samantaray S, Varghese M, Srinivasan A, Galoyan AA, Mohanakumar KP.

Neuropeptides. 2006 Aug;40(4):291-8. Epub 2006 May 18.

PMID:
16712929
12.

Paraquat neurotoxicity is distinct from that of MPTP and rotenone.

Richardson JR, Quan Y, Sherer TB, Greenamyre JT, Miller GW.

Toxicol Sci. 2005 Nov;88(1):193-201. Epub 2005 Sep 1.

14.

Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

L'Episcopo F, Tirolo C, Caniglia S, Testa N, Serra PA, Impagnatiello F, Morale MC, Marchetti B.

J Neuroinflammation. 2010 Nov 23;7:83. doi: 10.1186/1742-2094-7-83.

15.

Lamotrigine is neuroprotective in the energy deficiency model of MPTP intoxicated mice.

Lagrue E, Chalon S, Bodard S, Saliba E, Gressens P, Castelnau P.

Pediatr Res. 2007 Jul;62(1):14-9.

PMID:
17515828
16.
18.

Changes in neuronal dopamine homeostasis following 1-methyl-4-phenylpyridinium (MPP+) exposure.

Choi SJ, Panhelainen A, Schmitz Y, Larsen KE, Kanter E, Wu M, Sulzer D, Mosharov EV.

J Biol Chem. 2015 Mar 13;290(11):6799-809. doi: 10.1074/jbc.M114.631556. Epub 2015 Jan 16.

19.

Effect of dopaminergic neurotoxin MPTP/MPP+ on coenzyme Q content.

Dhanasekaran M, Karuppagounder SS, Uthayathas S, Wold LE, Parameshwaran K, Jayachandra Babu R, Suppiramaniam V, Brown-Borg H.

Life Sci. 2008 Jul 18;83(3-4):92-5. doi: 10.1016/j.lfs.2008.04.016. Epub 2008 May 6.

PMID:
18565546
20.
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