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Potential function of granulysin, other related effector molecules and lymphocyte subsets in patients with TB and HIV/TB coinfection.

Pitabut N, Sakurada S, Tanaka T, Ridruechai C, Tanuma J, Aoki T, Kantipong P, Piyaworawong S, Kobayashi N, Dhepakson P, Yanai H, Yamada N, Oka S, Okada M, Khusmith S, Keicho N.

Int J Med Sci. 2013 Jun 15;10(8):1003-14. doi: 10.7150/ijms.6437. Print 2013.


Plasma granulysin levels and cellular interferon-gamma production correlate with curative host responses in tuberculosis, while plasma interferon-gamma levels correlate with tuberculosis disease activity in adults.

Sahiratmadja E, Alisjahbana B, Buccheri S, Di Liberto D, de Boer T, Adnan I, van Crevel R, Klein MR, van Meijgaarden KE, Nelwan RH, van de Vosse E, Dieli F, Ottenhoff TH.

Tuberculosis (Edinb). 2007 Jul;87(4):312-21. Epub 2007 Mar 26.


Impaired expression of perforin and granulysin in CD8+ T cells at the site of infection in human chronic pulmonary tuberculosis.

Andersson J, Samarina A, Fink J, Rahman S, Grundström S.

Infect Immun. 2007 Nov;75(11):5210-22. Epub 2007 Jul 30.


Mycobacterium tuberculosis-specific CD8+ T cell recall in convalescing TB subjects with HIV co-infection.

Ongaya A, Huante MB, Mwangi P, Keiser PH, Amukoye E, Endsley JJ.

Tuberculosis (Edinb). 2013 Dec;93 Suppl:S60-5. doi: 10.1016/S1472-9792(13)70012-X.


Potent immune responses of Ag-specific Vgamma2Vdelta2+ T cells and CD8+ T cells associated with latent stage of Mycobacterium tuberculosis coinfection in HIV-1-infected humans.

Shao L, Zhang W, Zhang S, Chen CY, Jiang W, Xu Y, Meng C, Weng X, Chen ZW.

AIDS. 2008 Nov 12;22(17):2241-50. doi: 10.1097/QAD.0b013e3283117f18.


Coordinate expression of CC chemokine ligand 5, granulysin, and perforin in CD8+ T cells provides a host defense mechanism against Mycobacterium tuberculosis.

Stegelmann F, Bastian M, Swoboda K, Bhat R, Kiessler V, Krensky AM, Roellinghoff M, Modlin RL, Stenger S.

J Immunol. 2005 Dec 1;175(11):7474-83.


Granulysin-expressing CD4+ T cells as candidate immune marker for tuberculosis during childhood and adolescence.

Mueller H, Faé KC, Magdorf K, Ganoza CA, Wahn U, Guhlich U, Feiterna-Sperling C, Kaufmann SH.

PLoS One. 2011;6(12):e29367. doi: 10.1371/journal.pone.0029367. Epub 2011 Dec 27.


Decreased plasma granulysin and increased interferon-gamma concentrations in patients with newly diagnosed and relapsed tuberculosis.

Pitabut N, Mahasirimongkol S, Yanai H, Ridruechai C, Sakurada S, Dhepakson P, Kantipong P, Piyaworawong S, Moolphate S, Hansudewechakul C, Yamada N, Keicho N, Okada M, Khusmith S.

Microbiol Immunol. 2011 Aug;55(8):565-73. doi: 10.1111/j.1348-0421.2011.00348.x.


Activation of NK cell granulysin by mycobacteria and IL-15 is differentially affected by HIV.

Hogg A, Huante M, Ongaya A, Williams J, Ferguson M, Cloyd M, Amukoye E, Endsley J.

Tuberculosis (Edinb). 2011 Dec;91 Suppl 1:S75-81. doi: 10.1016/ Epub 2011 Nov 17.


Dynamics of adrenal steroids are related to variations in Th1 and Treg populations during Mycobacterium tuberculosis infection in HIV positive persons.

Quiroga MF, Angerami MT, Santucci N, Ameri D, Francos JL, Wallach J, Sued O, Cahn P, Salomón H, Bottasso O.

PLoS One. 2012;7(3):e33061. doi: 10.1371/journal.pone.0033061. Epub 2012 Mar 14.


CD4(+) and CD8(+) T cells kill intracellular Mycobacterium tuberculosis by a perforin and Fas/Fas ligand-independent mechanism.

Canaday DH, Wilkinson RJ, Li Q, Harding CV, Silver RF, Boom WH.

J Immunol. 2001 Sep 1;167(5):2734-42.


Decreased serum granulysin levels in childhood tuberculosis which reverse after therapy.

Di Liberto D, Buccheri S, Caccamo N, Meraviglia S, Romano A, Di Carlo P, Titone L, Dieli F, Krensky AM, Salerno A.

Tuberculosis (Edinb). 2007 Jul;87(4):322-8. Epub 2007 Mar 26.


Differential expression of granulysin and perforin by NK cells in cancer patients and correlation of impaired granulysin expression with progression of cancer.

Kishi A, Takamori Y, Ogawa K, Takano S, Tomita S, Tanigawa M, Niman M, Kishida T, Fujita S.

Cancer Immunol Immunother. 2002 Jan;50(11):604-14. Epub 2001 Nov 22.


Induction of granulysin in CD8+ T cells by IL-21 and IL-15 is suppressed by human immunodeficiency virus-1.

Hogg AE, Bowick GC, Herzog NK, Cloyd MW, Endsley JJ.

J Leukoc Biol. 2009 Nov;86(5):1191-203. doi: 10.1189/jlb.0409222. Epub 2009 Aug 17.


Granulysin-dependent killing of intracellular and extracellular Mycobacterium tuberculosis by Vgamma9/Vdelta2 T lymphocytes.

Dieli F, Troye-Blomberg M, Ivanyi J, Fournié JJ, Krensky AM, Bonneville M, Peyrat MA, Caccamo N, Sireci G, Salerno A.

J Infect Dis. 2001 Oct 15;184(8):1082-5. Epub 2001 Sep 28.


Natural-killer cell-derived cytolytic molecules in HIV-associated pulmonary tuberculosis-role of exogenous interleukins.

Rao PV, Ramanavelan S, Rajasekaran S, Raja A.

J Clin Immunol. 2010 May;30(3):393-401. doi: 10.1007/s10875-010-9380-y. Epub 2010 Mar 13.


Alteration of CD8+ T cell effector diversity during HIV-1 infection with discordant normalization in effective antiretroviral therapy.

Onlamoon N, Sukapirom K, Polsrila K, Ammaranond P, Pattanapanyasat K.

Cytometry B Clin Cytom. 2012 Jan;82(1):35-42. doi: 10.1002/cyto.b.20616. Epub 2011 Sep 13.


Induction of granulysin and perforin cytolytic mediator expression in 10-week-old infants vaccinated with BCG at birth.

Semple PL, Watkins M, Davids V, Krensky AM, Hanekom WA, Kaplan G, Ress S.

Clin Dev Immunol. 2011;2011:438463. doi: 10.1155/2011/438463. Epub 2010 Dec 28.

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