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Results: 1 to 20 of 111

1.

Detection of inhibitors of phenotypically drug-tolerant Mycobacterium tuberculosis using an in vitro bactericidal screen.

Bassett IM, Lun S, Bishai WR, Guo H, Kirman JR, Altaf M, O'Toole RF.

J Microbiol. 2013 Oct;51(5):651-8. doi: 10.1007/s12275-013-3099-4. Epub 2013 Jun 25.

PMID:
23800952
[PubMed - indexed for MEDLINE]
2.
3.

Targeting the chromosome partitioning protein ParA in tuberculosis drug discovery.

Nisa S, Blokpoel MC, Robertson BD, Tyndall JD, Lun S, Bishai WR, O'Toole R.

J Antimicrob Chemother. 2010 Nov;65(11):2347-58. doi: 10.1093/jac/dkq311. Epub 2010 Sep 1.

PMID:
20810423
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Evaluation of the Mycobacterium smegmatis and BCG models for the discovery of Mycobacterium tuberculosis inhibitors.

Altaf M, Miller CH, Bellows DS, O'Toole R.

Tuberculosis (Edinb). 2010 Nov;90(6):333-7. doi: 10.1016/j.tube.2010.09.002. Epub 2010 Oct 12.

PMID:
20933470
[PubMed - indexed for MEDLINE]
5.

Evaluation of Mycobacterium smegmatis as a possible surrogate screen for selecting molecules active against multi-drug resistant Mycobacterium tuberculosis.

Chaturvedi V, Dwivedi N, Tripathi RP, Sinha S.

J Gen Appl Microbiol. 2007 Dec;53(6):333-7.

PMID:
18187888
[PubMed - indexed for MEDLINE]
Free Article
6.

Antimycobacterial screening of traditional medicinal plants using the microplate resazurin assay.

Webster D, Lee TD, Moore J, Manning T, Kunimoto D, LeBlanc D, Johnson JA, Gray CA.

Can J Microbiol. 2010 Jun;56(6):487-94. doi: 10.1139/w10-035.

PMID:
20657619
[PubMed - indexed for MEDLINE]
7.

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis.

Guzman JD, Gupta A, Evangelopoulos D, Basavannacharya C, Pabon LC, Plazas EA, Muñoz DR, Delgado WA, Cuca LE, Ribon W, Gibbons S, Bhakta S.

J Antimicrob Chemother. 2010 Oct;65(10):2101-7. doi: 10.1093/jac/dkq313. Epub 2010 Aug 18.

PMID:
20719764
[PubMed - indexed for MEDLINE]
Free Article
8.

Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen.

Ramón-García S, Ng C, Anderson H, Chao JD, Zheng X, Pfeifer T, Av-Gay Y, Roberge M, Thompson CJ.

Antimicrob Agents Chemother. 2011 Aug;55(8):3861-9. doi: 10.1128/AAC.00474-11. Epub 2011 May 16.

PMID:
21576426
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

An integrated surrogate model for screening of drugs against Mycobacterium tuberculosis.

Gupta A, Bhakta S.

J Antimicrob Chemother. 2012 Jun;67(6):1380-91. doi: 10.1093/jac/dks056. Epub 2012 Mar 7.

PMID:
22398649
[PubMed - indexed for MEDLINE]
Free Article
10.

Fast-growing, non-infectious and intracellularly surviving drug-resistant Mycobacterium aurum: a model for high-throughput antituberculosis drug screening.

Gupta A, Bhakta S, Kundu S, Gupta M, Srivastava BS, Srivastava R.

J Antimicrob Chemother. 2009 Oct;64(4):774-81. doi: 10.1093/jac/dkp279. Epub 2009 Aug 4.

PMID:
19656786
[PubMed - indexed for MEDLINE]
Free Article
11.

Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.

Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.

Lett Appl Microbiol. 2011 Jan;52(1):33-40. doi: 10.1111/j.1472-765X.2010.02963.x. Epub 2010 Nov 29.

PMID:
21114505
[PubMed - indexed for MEDLINE]
12.

In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide.

Villar R, Vicente E, Solano B, Pérez-Silanes S, Aldana I, Maddry JA, Lenaerts AJ, Franzblau SG, Cho SH, Monge A, Goldman RC.

J Antimicrob Chemother. 2008 Sep;62(3):547-54. doi: 10.1093/jac/dkn214. Epub 2008 May 23.

PMID:
18502817
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Decreased outer membrane permeability protects mycobacteria from killing by ubiquitin-derived peptides.

Purdy GE, Niederweis M, Russell DG.

Mol Microbiol. 2009 Sep;73(5):844-57. doi: 10.1111/j.1365-2958.2009.06801.x. Epub 2009 Aug 6.

PMID:
19682257
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Evaluation of nitrate reduction assay, resazurin microtiter assay and microscopic observation drug susceptibility assay for first line antitubercular drug susceptibility testing of clinical isolates of M. tuberculosis.

Dixit P, Singh U, Sharma P, Jain A.

J Microbiol Methods. 2012 Jan;88(1):122-6. doi: 10.1016/j.mimet.2011.11.006. Epub 2011 Nov 26.

PMID:
22133919
[PubMed - indexed for MEDLINE]
15.

Bactericidal activity of 2-nitroimidazole against the active replicating stage of Mycobacterium bovis BCG and Mycobacterium tuberculosis with intracellular efficacy in THP-1 macrophages.

Khan A, Sarkar S, Sarkar D.

Int J Antimicrob Agents. 2008 Jul;32(1):40-5. doi: 10.1016/j.ijantimicag.2008.02.022. Epub 2008 Jun 5.

PMID:
18538548
[PubMed - indexed for MEDLINE]
16.

A novel screening method based on menadione mediated rapid reduction of tetrazolium salt for testing of anti-mycobacterial agents.

Singh U, Akhtar S, Mishra A, Sarkar D.

J Microbiol Methods. 2011 Feb;84(2):202-7. doi: 10.1016/j.mimet.2010.11.013. Epub 2010 Dec 1.

PMID:
21129420
[PubMed - indexed for MEDLINE]
17.

Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.

Miller CH, Nisa S, Dempsey S, Jack C, O'Toole R.

Antimicrob Agents Chemother. 2009 Dec;53(12):5279-83. doi: 10.1128/AAC.00803-09. Epub 2009 Sep 28.

PMID:
19786608
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The abyssomicin C family as in vitro inhibitors of Mycobacterium tuberculosis.

Freundlich JS, Lalgondar M, Wei JR, Swanson S, Sorensen EJ, Rubin EJ, Sacchettini JC.

Tuberculosis (Edinb). 2010 Sep;90(5):298-300. doi: 10.1016/j.tube.2010.08.002. Epub 2010 Aug 23.

PMID:
20739223
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Development of a microdilution method to evaluate Mycobacterium tuberculosis drug susceptibility.

Banfi E, Scialino G, Monti-Bragadin C.

J Antimicrob Chemother. 2003 Nov;52(5):796-800. Epub 2003 Sep 30.

PMID:
14519676
[PubMed - indexed for MEDLINE]
Free Article
20.

Tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide and N-benzyl-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3.

Remuiñán MJ, Pérez-Herrán E, Rullás J, Alemparte C, Martínez-Hoyos M, Dow DJ, Afari J, Mehta N, Esquivias J, Jiménez E, Ortega-Muro F, Fraile-Gabaldón MT, Spivey VL, Loman NJ, Pallen MJ, Constantinidou C, Minick DJ, Cacho M, Rebollo-López MJ, González C, Sousa V, Angulo-Barturen I, Mendoza-Losana A, Barros D, Besra GS, Ballell L, Cammack N.

PLoS One. 2013 Apr 17;8(4):e60933. doi: 10.1371/journal.pone.0060933. Print 2013.

PMID:
23613759
[PubMed - indexed for MEDLINE]
Free PMC Article

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