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1.

Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila.

Lőw P, Varga Á, Pircs K, Nagy P, Szatmári Z, Sass M, Juhász G.

BMC Cell Biol. 2013 Jun 25;14:29. doi: 10.1186/1471-2121-14-29.

2.

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway.

Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L.

J Biol Chem. 1999 Mar 5;274(10):6519-25.

4.

Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment.

Martinez-Outschoorn UE, Trimmer C, Lin Z, Whitaker-Menezes D, Chiavarina B, Zhou J, Wang C, Pavlides S, Martinez-Cantarin MP, Capozza F, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Caro J, Lisanti MP, Sotgia F.

Cell Cycle. 2010 Sep 1;9(17):3515-33. Epub 2010 Sep 9.

5.

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS.

Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, Nedelsky NB, Schwartz SL, DiProspero NA, Knight MA, Schuldiner O, Padmanabhan R, Hild M, Berry DL, Garza D, Hubbert CC, Yao TP, Baehrecke EH, Taylor JP.

Nature. 2007 Jun 14;447(7146):859-63.

PMID:
17568747
6.
7.

The insulin-PI3K/TOR pathway induces a HIF-dependent transcriptional response in Drosophila by promoting nuclear localization of HIF-alpha/Sima.

Dekanty A, Lavista-Llanos S, Irisarri M, Oldham S, Wappner P.

J Cell Sci. 2005 Dec 1;118(Pt 23):5431-41. Epub 2005 Nov 8.

8.
9.

Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins.

Srinivas V, Zhang LP, Zhu XH, Caro J.

Biochem Biophys Res Commun. 1999 Jul 5;260(2):557-61.

PMID:
10403805
10.
11.
12.

A novel crosstalk between two major protein degradation systems: regulation of proteasomal activity by autophagy.

Wang XJ, Yu J, Wong SH, Cheng AS, Chan FK, Ng SS, Cho CH, Sung JJ, Wu WK.

Autophagy. 2013 Oct;9(10):1500-8. doi: 10.4161/auto.25573. Epub 2013 Jul 11.

PMID:
23934082
13.

Activation of peroxisome proliferator-activated receptor α (PPARα) suppresses hypoxia-inducible factor-1α (HIF-1α) signaling in cancer cells.

Zhou J, Zhang S, Xue J, Avery J, Wu J, Lind SE, Ding WQ.

J Biol Chem. 2012 Oct 12;287(42):35161-9. doi: 10.1074/jbc.M112.367367. Epub 2012 Aug 29.

14.

Substrate recognition in selective autophagy and the ubiquitin-proteasome system.

Schreiber A, Peter M.

Biochim Biophys Acta. 2014 Jan;1843(1):163-81. doi: 10.1016/j.bbamcr.2013.03.019. Epub 2013 Mar 29. Review.

15.

Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins.

Rajakumar A, Michael HM, Daftary A, Jeyabalan A, Gilmour C, Conrad KP.

Placenta. 2008 Mar;29(3):290-9. doi: 10.1016/j.placenta.2007.11.015. Epub 2008 Jan 28.

PMID:
18222538
16.

Regulation of the Drosophila bHLH-PAS protein Sima by hypoxia: functional evidence for homology with mammalian HIF-1 alpha.

Bacon NC, Wappner P, O'Rourke JF, Bartlett SM, Shilo B, Pugh CW, Ratcliffe PJ.

Biochem Biophys Res Commun. 1998 Aug 28;249(3):811-6.

PMID:
9731218
17.

Activation of hypoxia-induced transcription in normoxia.

Hägg M, Wennström S.

Exp Cell Res. 2005 May 15;306(1):180-91. Epub 2005 Mar 19.

PMID:
15878343
18.

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein.

Tanimoto K, Makino Y, Pereira T, Poellinger L.

EMBO J. 2000 Aug 15;19(16):4298-309.

19.

Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation.

Hubbi ME, Hu H, Kshitiz, Ahmed I, Levchenko A, Semenza GL.

J Biol Chem. 2013 Apr 12;288(15):10703-14. doi: 10.1074/jbc.M112.414771. Epub 2013 Mar 1.

20.

Autophagy regulates hypoxia-induced osteoclastogenesis through the HIF-1α/BNIP3 signaling pathway.

Zhao Y, Chen G, Zhang W, Xu N, Zhu JY, Jia J, Sun ZJ, Wang YN, Zhao YF.

J Cell Physiol. 2012 Feb;227(2):639-48. doi: 10.1002/jcp.22768.

PMID:
21465467
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