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Results: 1 to 20 of 105

1.

Metabolic signatures of GS-CHO cell clones associated with butyrate treatment and culture phase transition.

Carinhas N, Duarte TM, Barreiro LC, Carrondo MJ, Alves PM, Teixeira AP.

Biotechnol Bioeng. 2013 Dec;110(12):3244-57. doi: 10.1002/bit.24983. Epub 2013 Jul 7.

PMID:
23794452
[PubMed - indexed for MEDLINE]
2.

A kinetic-metabolic model based on cell energetic state: study of CHO cell behavior under Na-butyrate stimulation.

Ghorbaniaghdam A, Henry O, Jolicoeur M.

Bioprocess Biosyst Eng. 2013 Apr;36(4):469-87. doi: 10.1007/s00449-012-0804-3. Epub 2012 Sep 14.

PMID:
22976819
[PubMed - indexed for MEDLINE]
3.

Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.

Fan L, Kadura I, Krebs LE, Hatfield CC, Shaw MM, Frye CC.

Biotechnol Bioeng. 2012 Apr;109(4):1007-15. doi: 10.1002/bit.24365. Epub 2011 Nov 21.

PMID:
22068567
[PubMed - indexed for MEDLINE]
4.

Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry.

Ahn WS, Antoniewicz MR.

Metab Eng. 2011 Sep;13(5):598-609. doi: 10.1016/j.ymben.2011.07.002. Epub 2011 Aug 2.

PMID:
21821143
[PubMed - indexed for MEDLINE]
5.

Transcriptome and proteome analysis of Chinese hamster ovary cells under low temperature and butyrate treatment.

Kantardjieff A, Jacob NM, Yee JC, Epstein E, Kok YJ, Philp R, Betenbaugh M, Hu WS.

J Biotechnol. 2010 Jan 15;145(2):143-59. doi: 10.1016/j.jbiotec.2009.09.008. Epub 2009 Sep 19.

PMID:
19770009
[PubMed - indexed for MEDLINE]
6.

Metabolic analysis of antibody producing CHO cells in fed-batch production.

Dean J, Reddy P.

Biotechnol Bioeng. 2013 Jun;110(6):1735-47. doi: 10.1002/bit.24826. Epub 2013 Feb 15.

PMID:
23296898
[PubMed - indexed for MEDLINE]
7.

Na-butyrate sustains energetic states of metabolism and t-PA productivity of CHO cells.

McMurray-Beaulieu V, Hisiger S, Durand C, Perrier M, Jolicoeur M.

J Biosci Bioeng. 2009 Aug;108(2):160-7. doi: 10.1016/j.jbiosc.2009.03.001.

PMID:
19619865
[PubMed - indexed for MEDLINE]
8.

Metabolic responses of CHO cells to limitation of key amino acids.

Duarte TM, Carinhas N, Barreiro LC, Carrondo MJ, Alves PM, Teixeira AP.

Biotechnol Bioeng. 2014 Oct;111(10):2095-106. doi: 10.1002/bit.25266. Epub 2014 Jul 28.

PMID:
24771076
[PubMed - in process]
9.

Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed-batch CHO cell culture.

Templeton N, Dean J, Reddy P, Young JD.

Biotechnol Bioeng. 2013 Jul;110(7):2013-24. doi: 10.1002/bit.24858. Epub 2013 Mar 4.

PMID:
23381838
[PubMed - indexed for MEDLINE]
10.

Metabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [13C, 1H] COSY NMR spectroscopy.

Goudar C, Biener R, Boisart C, Heidemann R, Piret J, de Graaf A, Konstantinov K.

Metab Eng. 2010 Mar;12(2):138-49. doi: 10.1016/j.ymben.2009.10.007. Epub 2009 Nov 5.

PMID:
19896555
[PubMed - indexed for MEDLINE]
11.

A single nutrient feed supports both chemically defined NS0 and CHO fed-batch processes: Improved productivity and lactate metabolism.

Ma N, Ellet J, Okediadi C, Hermes P, McCormick E, Casnocha S.

Biotechnol Prog. 2009 Sep-Oct;25(5):1353-63. doi: 10.1002/btpr.238.

PMID:
19637321
[PubMed - indexed for MEDLINE]
12.

Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells.

Burleigh SC, van de Laar T, Stroop CJ, van Grunsven WM, O'Donoghue N, Rudd PM, Davey GP.

BMC Biotechnol. 2011 Oct 18;11:95. doi: 10.1186/1472-6750-11-95.

PMID:
22008152
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Fluorescent proteins in animal cells for process development: optimization of sodium butyrate treatment as an example.

Hunt L, Batard P, Jordan M, Wurm FM.

Biotechnol Bioeng. 2002 Mar 5;77(5):528-37.

PMID:
11788951
[PubMed - indexed for MEDLINE]
14.

Dependence on glucose limitation of the pCO2 influences on CHO cell growth, metabolism and IgG production.

Takuma S, Hirashima C, Piret JM.

Biotechnol Bioeng. 2007 Aug 15;97(6):1479-88.

PMID:
17318909
[PubMed - indexed for MEDLINE]
16.

Metabolite profiling of recombinant CHO cells: designing tailored feeding regimes that enhance recombinant antibody production.

Sellick CA, Croxford AS, Maqsood AR, Stephens G, Westerhoff HV, Goodacre R, Dickson AJ.

Biotechnol Bioeng. 2011 Dec;108(12):3025-31. doi: 10.1002/bit.23269. Epub 2011 Aug 10.

PMID:
21769861
[PubMed - indexed for MEDLINE]
17.

Effect of N-Acetylcystein on butyrate-treated Chinese hamster ovary cells to improve the production of recombinant human interferon-beta-1a.

Oh HK, So MK, Yang J, Yoon HC, Ahn JS, Lee JM, Kim JT, Yoo JU, Byun TH.

Biotechnol Prog. 2005 Jul-Aug;21(4):1154-64.

PMID:
16080696
[PubMed - indexed for MEDLINE]
18.

Towards dynamic metabolic flux analysis in CHO cell cultures.

Ahn WS, Antoniewicz MR.

Biotechnol J. 2012 Jan;7(1):61-74. doi: 10.1002/biot.201100052. Epub 2011 Nov 21. Review.

PMID:
22102428
[PubMed - indexed for MEDLINE]
19.

Determination of Chinese hamster ovary cell line stability and recombinant antibody expression during long-term culture.

Bailey LA, Hatton D, Field R, Dickson AJ.

Biotechnol Bioeng. 2012 Aug;109(8):2093-103.

PMID:
22896849
[PubMed - indexed for MEDLINE]
20.

Sodium butyrate stimulates monoclonal antibody over-expression in CHO cells by improving gene accessibility.

Jiang Z, Sharfstein ST.

Biotechnol Bioeng. 2008 May 1;100(1):189-94.

PMID:
18023047
[PubMed - indexed for MEDLINE]

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