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The expression of intronic miRNAs, miR-483 and miR-483*, and their host gene, Igf2, in murine osteoarthritis cartilage.

Qi Y, Ma N, Yan F, Yu Z, Wu G, Qiao Y, Han D, Xiang Y, Li F, Wang W, Gao X.

Int J Biol Macromol. 2013 Oct;61:43-9. doi: 10.1016/j.ijbiomac.2013.06.006. Epub 2013 Jun 17.


MicroRNA-488 regulates zinc transporter SLC39A8/ZIP8 during pathogenesis of osteoarthritis.

Song J, Kim D, Lee CH, Lee MS, Chun CH, Jin EJ.

J Biomed Sci. 2013 May 20;20:31. doi: 10.1186/1423-0127-20-31.


Expression of intronic miRNAs and their host gene Igf2 in a murine unilateral ureteral obstruction model.

Li NQ, Yang J, Cui L, Ma N, Zhang L, Hao LR.

Braz J Med Biol Res. 2015 Jun;48(6):486-92. doi: 10.1590/1414-431X20143958. Epub 2015 Mar 27.


Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks.

Iliopoulos D, Malizos KN, Oikonomou P, Tsezou A.

PLoS One. 2008;3(11):e3740. doi: 10.1371/journal.pone.0003740. Epub 2008 Nov 17.


Regulation of H19 and its encoded microRNA-675 in osteoarthritis and under anabolic and catabolic in vitro conditions.

Steck E, Boeuf S, Gabler J, Werth N, Schnatzer P, Diederichs S, Richter W.

J Mol Med (Berl). 2012 Oct;90(10):1185-95. doi: 10.1007/s00109-012-0895-y. Epub 2012 Apr 21.


Coexpression of an intronic microRNA and its host gene reveals a potential role for miR-483-5p as an IGF2 partner.

Ma N, Wang X, Qiao Y, Li F, Hui Y, Zou C, Jin J, Lv G, Peng Y, Wang L, Huang H, Zhou L, Zheng X, Gao X.

Mol Cell Endocrinol. 2011 Feb 10;333(1):96-101. doi: 10.1016/j.mce.2010.11.027. Epub 2010 Dec 10.


The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13.

Jones SW, Watkins G, Le Good N, Roberts S, Murphy CL, Brockbank SM, Needham MR, Read SJ, Newham P.

Osteoarthritis Cartilage. 2009 Apr;17(4):464-72. doi: 10.1016/j.joca.2008.09.012. Epub 2008 Oct 11.


MMP13 is a critical target gene during the progression of osteoarthritis.

Wang M, Sampson ER, Jin H, Li J, Ke QH, Im HJ, Chen D.

Arthritis Res Ther. 2013 Jan 8;15(1):R5. doi: 10.1186/ar4133.


NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis.

Tardif G, Pelletier JP, Fahmi H, Hum D, Zhang Y, Kapoor M, Martel-Pelletier J.

Arthritis Res Ther. 2013;15(6):R197.


Two non-coding RNAs, MicroRNA-101 and HOTTIP contribute cartilage integrity by epigenetic and homeotic regulation of integrin-α1.

Kim D, Song J, Han J, Kim Y, Chun CH, Jin EJ.

Cell Signal. 2013 Dec;25(12):2878-87. doi: 10.1016/j.cellsig.2013.08.034. Epub 2013 Sep 7.


The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis.

Santini P, Politi L, Vedova PD, Scandurra R, Scotto d'Abusco A.

Rheumatol Int. 2014 May;34(5):711-6. doi: 10.1007/s00296-013-2754-8. Epub 2013 Apr 18.


Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.

Tardif G, Hum D, Pelletier JP, Duval N, Martel-Pelletier J.

BMC Musculoskelet Disord. 2009 Nov 30;10:148. doi: 10.1186/1471-2474-10-148.


Interleukin-6 plays an essential role in hypoxia-inducible factor 2α-induced experimental osteoarthritic cartilage destruction in mice.

Ryu JH, Yang S, Shin Y, Rhee J, Chun CH, Chun JS.

Arthritis Rheum. 2011 Sep;63(9):2732-43. doi: 10.1002/art.30451.


Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes.

Díaz-Prado S, Cicione C, Muiños-López E, Hermida-Gómez T, Oreiro N, Fernández-López C, Blanco FJ.

BMC Musculoskelet Disord. 2012 Aug 12;13:144. doi: 10.1186/1471-2474-13-144.


MicroRNA-558 regulates the expression of cyclooxygenase-2 and IL-1β-induced catabolic effects in human articular chondrocytes.

Park SJ, Cheon EJ, Kim HA.

Osteoarthritis Cartilage. 2013 Jul;21(7):981-9. doi: 10.1016/j.joca.2013.04.012. Epub 2013 Apr 20.


Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.

Blaney Davidson EN, Remst DF, Vitters EL, van Beuningen HM, Blom AB, Goumans MJ, van den Berg WB, van der Kraan PM.

J Immunol. 2009 Jun 15;182(12):7937-45. doi: 10.4049/jimmunol.0803991. Erratum in: J Immunol. 2010 Aug 15;185(4):2629.


Molecular mechanisms of the cartilage-specific microRNA-140 in osteoarthritis.

Zhang R, Ma J, Yao J.

Inflamm Res. 2013 Oct;62(10):871-7. doi: 10.1007/s00011-013-0654-8. Epub 2013 Aug 14. Review.


Global analyses of gene expression in early experimental osteoarthritis.

Appleton CT, Pitelka V, Henry J, Beier F.

Arthritis Rheum. 2007 Jun;56(6):1854-68.


In vivo osteoarthritis target validation utilizing genetically-modified mice.

Glasson SS.

Curr Drug Targets. 2007 Feb;8(2):367-76. Review.

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