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Items: 1 to 20 of 101

1.

KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces intrauterine growth restriction in mice.

Abe N, Nakahara T, Morita A, Wada Y, Mori A, Sakamoto K, Nagamitsu T, Ishii K.

Birth Defects Res B Dev Reprod Toxicol. 2013 Aug;98(4):297-303. doi: 10.1002/bdrb.21064. Epub 2013 Jun 18.

PMID:
23780833
2.

Effects of KRN633, an inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase, on vascular development of placenta and fetus of mid-pregnancy in mice.

Wada Y, Ozaki H, Abe N, Nagamitsu T, Ohta H, Nakahara T, Ishii K.

J Pharmacol Sci. 2010;112(3):290-8. Epub 2010 Mar 2.

3.

Treatment of mid-pregnant mice with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces abnormal retinal vascular patterning in their newborn pups.

Morita A, Nakahara T, Abe N, Kurauchi Y, Mori A, Sakamoto K, Nagamitsu T, Ishii K.

Birth Defects Res B Dev Reprod Toxicol. 2014 Aug;101(4):293-9. doi: 10.1002/bdrb.21112. Epub 2014 May 15.

PMID:
24831925
4.

Effects of pre- and post-natal treatment with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, on retinal vascular development and patterning in mice.

Morita A, Nakahara T, Abe N, Kurauchi Y, Mori A, Sakamoto K, Nagamitsu T, Ishii K.

Exp Eye Res. 2014 Mar;120:127-37. doi: 10.1016/j.exer.2014.01.009. Epub 2014 Jan 23.

PMID:
24462631
5.

Short-term treatment with VEGF receptor inhibitors induces retinopathy of prematurity-like abnormal vascular growth in neonatal rats.

Nakano A, Nakahara T, Mori A, Ushikubo H, Sakamoto K, Ishii K.

Exp Eye Res. 2016 Feb;143:120-31. doi: 10.1016/j.exer.2015.10.016. Epub 2015 Oct 22.

PMID:
26500193
6.

KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth.

Nakamura K, Yamamoto A, Kamishohara M, Takahashi K, Taguchi E, Miura T, Kubo K, Shibuya M, Isoe T.

Mol Cancer Ther. 2004 Dec;3(12):1639-49.

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Induction of intrauterine growth restriction by reducing placental vascular growth with the angioinhibin TNP-470.

Rutland CS, Mukhopadhyay M, Underwood S, Clyde N, Mayhew TM, Mitchell CA.

Biol Reprod. 2005 Dec;73(6):1164-73. Epub 2005 Aug 3.

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Effects of mTOR inhibition on normal retinal vascular development in the mouse.

Yagasaki R, Nakahara T, Mori A, Sakamoto K, Ishii K.

Exp Eye Res. 2014 Dec;129:127-34. doi: 10.1016/j.exer.2014.11.005. Epub 2014 Nov 8.

PMID:
25446323
13.

Suppression of hypoxia-induced HIF-1alpha accumulation by VEGFR inhibitors: Different profiles of AAL993 versus SU5416 and KRN633.

Ban HS, Uno M, Nakamura H.

Cancer Lett. 2010 Oct 1;296(1):17-26. doi: 10.1016/j.canlet.2010.03.010. Epub 2010 Apr 7.

PMID:
20378243
14.

Endothelial NO synthase augments fetoplacental blood flow, placental vascularization, and fetal growth in mice.

Kulandavelu S, Whiteley KJ, Bainbridge SA, Qu D, Adamson SL.

Hypertension. 2013 Jan;61(1):259-66. doi: 10.1161/HYPERTENSIONAHA.112.201996. Epub 2012 Nov 12.

15.

Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy.

Ciardiello F, Bianco R, Caputo R, Caputo R, Damiano V, Troiani T, Melisi D, De Vita F, De Placido S, Bianco AR, Tortora G.

Clin Cancer Res. 2004 Jan 15;10(2):784-93.

16.

Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves the antiangiogenic efficacy for advanced stage mouse corneal neovascularization.

Chaoran Z, Zhirong L, Gezhi X.

Graefes Arch Clin Exp Ophthalmol. 2011 Oct;249(10):1493-501. doi: 10.1007/s00417-011-1709-6. Epub 2011 May 15.

PMID:
21574021
17.

Role of vascular endothelial growth factor in maintenance of pregnancy in mice.

Wada Y, Ozaki H, Abe N, Mori A, Sakamoto K, Nagamitsu T, Nakahara T, Ishii K.

Endocrinology. 2013 Feb;154(2):900-10. doi: 10.1210/en.2012-1967. Epub 2013 Jan 10.

PMID:
23307787
18.

Expression of VEGF-C and activation of its receptors VEGFR-2 and VEGFR-3 in trophoblast.

Dunk C, Ahmed A.

Histol Histopathol. 2001 Apr;16(2):359-75.

PMID:
11332691
19.
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