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Results: 1 to 20 of 193

1.

Androgen metabolite-dependent growth of hormone receptor-positive breast cancer as a possible aromatase inhibitor-resistance mechanism.

Hanamura T, Niwa T, Nishikawa S, Konno H, Gohno T, Tazawa C, Kobayashi Y, Kurosumi M, Takei H, Yamaguchi Y, Ito K, Hayashi S.

Breast Cancer Res Treat. 2013 Jun;139(3):731-40. doi: 10.1007/s10549-013-2595-x. Epub 2013 Jun 19.

PMID:
23780684
[PubMed - indexed for MEDLINE]
2.

Possible role of the aromatase-independent steroid metabolism pathways in hormone responsive primary breast cancers.

Hanamura T, Niwa T, Gohno T, Kurosumi M, Takei H, Yamaguchi Y, Ito K, Hayashi S.

Breast Cancer Res Treat. 2014 Jan;143(1):69-80. doi: 10.1007/s10549-013-2788-3. Epub 2013 Nov 30.

PMID:
24292869
[PubMed - indexed for MEDLINE]
3.

The androgen metabolite 5alpha-androstane-3beta,17beta-diol (3betaAdiol) induces breast cancer growth via estrogen receptor: implications for aromatase inhibitor resistance.

Sikora MJ, Cordero KE, Larios JM, Johnson MD, Lippman ME, Rae JM.

Breast Cancer Res Treat. 2009 May;115(2):289-96. doi: 10.1007/s10549-008-0080-8. Epub 2008 Jun 4.

PMID:
18521740
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Interaction of Androst-5-ene-3β,17β-diol and 5α-androstane-3β,17β-diol with estrogen and androgen receptors: a combined binding and cell study.

Chen J, Wang WQ, Lin SX.

J Steroid Biochem Mol Biol. 2013 Sep;137:316-21. doi: 10.1016/j.jsbmb.2013.01.012. Epub 2013 Feb 14.

PMID:
23416106
[PubMed - indexed for MEDLINE]
6.

Enhanced formation of non-phenolic androgen metabolites with intrinsic oestrogen-like gene transactivation potency in human breast cancer cells: a distinctive metabolic pattern.

Pérez-Palacios G, Santillán R, García-Becerra R, Borja-Cacho E, Larrea F, Damián-Matsumura P, González L, Lemus AE.

J Endocrinol. 2006 Sep;190(3):805-18.

PMID:
17003281
[PubMed - indexed for MEDLINE]
Free Article
7.

Androgens upregulate cyp19a1b (aromatase B) gene expression in the brain of zebrafish (Danio rerio) through estrogen receptors.

Mouriec K, Gueguen MM, Manuel C, Percevault F, Thieulant ML, Pakdel F, Kah O.

Biol Reprod. 2009 May;80(5):889-96. doi: 10.1095/biolreprod.108.073643. Epub 2009 Jan 7.

PMID:
19129512
[PubMed - indexed for MEDLINE]
Free Article
8.

The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits prostate cancer cell migration through activation of the estrogen receptor beta subtype.

Guerini V, Sau D, Scaccianoce E, Rusmini P, Ciana P, Maggi A, Martini PG, Katzenellenbogen BS, Martini L, Motta M, Poletti A.

Cancer Res. 2005 Jun 15;65(12):5445-53.

PMID:
15958594
[PubMed - indexed for MEDLINE]
Free Article
9.

Hormonal regulation of steroidogenic enzyme gene expression in Leydig cells.

Payne AH, Youngblood GL, Sha L, Burgos-Trinidad M, Hammond SH.

J Steroid Biochem Mol Biol. 1992 Dec;43(8):895-906. doi: 10.1016/0960-0760(92)90317-C. Review.

PMID:
22217834
[PubMed - indexed for MEDLINE]
10.

Endogenous aromatization of testosterone results in growth stimulation of the human MCF-7 breast cancer cell line.

Sonne-Hansen K, Lykkesfeldt AE.

J Steroid Biochem Mol Biol. 2005 Jan;93(1):25-34. Epub 2005 Jan 27.

PMID:
15748829
[PubMed - indexed for MEDLINE]
11.

5Alpha-reductase type 1 and aromatase in breast carcinoma as regulators of in situ androgen production.

Suzuki T, Miki Y, Moriya T, Akahira J, Ishida T, Hirakawa H, Yamaguchi Y, Hayashi S, Sasano H.

Int J Cancer. 2007 Jan 15;120(2):285-91.

PMID:
17066438
[PubMed - indexed for MEDLINE]
12.

5alpha-Androstane-3beta,17beta-diol (3beta-diol), an estrogenic metabolite of 5alpha-dihydrotestosterone, is a potent modulator of estrogen receptor ERbeta expression in the ventral prostrate of adult rats.

Oliveira AG, Coelho PH, Guedes FD, Mahecha GA, Hess RA, Oliveira CA.

Steroids. 2007 Dec;72(14):914-22. Epub 2007 Aug 9.

PMID:
17854852
[PubMed - indexed for MEDLINE]
13.

Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men.

Blouin K, Richard C, Brochu G, Hould FS, Lebel S, Marceau S, Biron S, Luu-The V, Tchernof A.

J Endocrinol. 2006 Dec;191(3):637-49.

PMID:
17170221
[PubMed - indexed for MEDLINE]
Free Article
14.

Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole.

Macedo LF, Guo Z, Tilghman SL, Sabnis GJ, Qiu Y, Brodie A.

Cancer Res. 2006 Aug 1;66(15):7775-82.

PMID:
16885381
[PubMed - indexed for MEDLINE]
Free Article
15.

Effects of steroidal aromatase inhibitors on sensitive and resistant breast cancer cells: aromatase inhibition and autophagy.

Amaral C, Varela C, Azevedo M, da Silva ET, Roleira FM, Chen S, Correia-da-Silva G, Teixeira N.

J Steroid Biochem Mol Biol. 2013 May;135:51-9. doi: 10.1016/j.jsbmb.2012.12.017. Epub 2013 Jan 11.

PMID:
23318878
[PubMed - indexed for MEDLINE]
16.

The androgen metabolite, 5α-androstane-3β,17β-diol (3β-diol), activates the oxytocin promoter through an estrogen receptor-β pathway.

Hiroi R, Lacagnina AF, Hinds LR, Carbone DG, Uht RM, Handa RJ.

Endocrinology. 2013 May;154(5):1802-12. doi: 10.1210/en.2012-2253. Epub 2013 Mar 20.

PMID:
23515287
[PubMed - indexed for MEDLINE]
Free PMC Article
17.
19.

Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer.

Weigel MT, Ghazoui Z, Dunbier A, Pancholi S, Dowsett M, Martin LA.

Breast Cancer Res. 2012 May 18;14(3):R78.

PMID:
22608253
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

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