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Results: 1 to 20 of 133

1.

Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals.

Qiu J, Tan YW, Hagenston AM, Martel MA, Kneisel N, Skehel PA, Wyllie DJ, Bading H, Hardingham GE.

Nat Commun. 2013;4:2034. doi: 10.1038/ncomms3034.

PMID:
23774321
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.

Urushitani M, Nakamizo T, Inoue R, Sawada H, Kihara T, Honda K, Akaike A, Shimohama S.

J Neurosci Res. 2001 Mar 1;63(5):377-87.

PMID:
11223912
[PubMed - indexed for MEDLINE]
3.

Phosphoinositide 3-kinase couples NMDA receptors to superoxide release in excitotoxic neuronal death.

Brennan-Minnella AM, Shen Y, El-Benna J, Swanson RA.

Cell Death Dis. 2013 Apr 4;4:e580. doi: 10.1038/cddis.2013.111. Erratum in: Cell Death Dis. 2013;4:e624. El-Benna, J [added].

PMID:
23559014
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells.

Alam MR, Groschner LN, Parichatikanond W, Kuo L, Bondarenko AI, Rost R, Waldeck-Weiermair M, Malli R, Graier WF.

J Biol Chem. 2012 Oct 5;287(41):34445-54. doi: 10.1074/jbc.M112.392084. Epub 2012 Aug 17.

PMID:
22904319
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.

Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.

Nat Cell Biol. 2012 Dec;14(12):1336-43. doi: 10.1038/ncb2622. Epub 2012 Nov 25. Erratum in: Nat Cell Biol. 2013 Jan;15(1):123.

PMID:
23178883
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.

Baughman JM, Perocchi F, Girgis HS, Plovanich M, Belcher-Timme CA, Sancak Y, Bao XR, Strittmatter L, Goldberger O, Bogorad RL, Koteliansky V, Mootha VK.

Nature. 2011 Jun 19;476(7360):341-5. doi: 10.1038/nature10234.

PMID:
21685886
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Protection by cholesterol-extracting cyclodextrins: a role for N-methyl-D-aspartate receptor redistribution.

Abulrob A, Tauskela JS, Mealing G, Brunette E, Faid K, Stanimirovic D.

J Neurochem. 2005 Mar;92(6):1477-86.

PMID:
15748165
[PubMed - indexed for MEDLINE]
8.

Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective effects.

Vizi ES, Kisfali M, Lőrincz T.

Brain Res Bull. 2013 Apr;93:32-8. doi: 10.1016/j.brainresbull.2012.10.005. Epub 2012 Oct 23. Review.

PMID:
23089362
[PubMed - indexed for MEDLINE]
9.

Mitochondrial calcium uptake.

Williams GS, Boyman L, Chikando AC, Khairallah RJ, Lederer WJ.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10479-86. doi: 10.1073/pnas.1300410110. Epub 2013 Jun 12. Review.

PMID:
23759742
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.

De Stefani D, Raffaello A, Teardo E, Szabò I, Rizzuto R.

Nature. 2011 Jun 19;476(7360):336-40. doi: 10.1038/nature10230.

PMID:
21685888
[PubMed - indexed for MEDLINE]
11.

ERp57 modulates mitochondrial calcium uptake through the MCU.

He J, Shi W, Guo Y, Chai Z.

FEBS Lett. 2014 Jun 5;588(12):2087-94. doi: 10.1016/j.febslet.2014.04.041. Epub 2014 May 8.

PMID:
24815697
[PubMed - indexed for MEDLINE]
12.

The role of mitochondrial calcium uniporter in neuroprotection in traumatic brain injury.

Cheng G, Fu L, Zhang HY, Wang YM, Zhang LM, Zhang JN.

Med Hypotheses. 2013 Feb;80(2):115-7. doi: 10.1016/j.mehy.2012.11.004. Epub 2012 Nov 27.

PMID:
23200456
[PubMed - indexed for MEDLINE]
13.

Excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons.

Churn SB, Limbrick D, Sombati S, DeLorenzo RJ.

J Neurosci. 1995 Apr;15(4):3200-14.

PMID:
7722657
[PubMed - indexed for MEDLINE]
Free Article
14.

A signaling cascade of nuclear calcium-CREB-ATF3 activated by synaptic NMDA receptors defines a gene repression module that protects against extrasynaptic NMDA receptor-induced neuronal cell death and ischemic brain damage.

Zhang SJ, Buchthal B, Lau D, Hayer S, Dick O, Schwaninger M, Veltkamp R, Zou M, Weiss U, Bading H.

J Neurosci. 2011 Mar 30;31(13):4978-90. doi: 10.1523/JNEUROSCI.2672-10.2011.

PMID:
21451036
[PubMed - indexed for MEDLINE]
Free Article
15.

Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity.

Arundine M, Tymianski M.

Cell Calcium. 2003 Oct-Nov;34(4-5):325-37. Review.

PMID:
12909079
[PubMed - indexed for MEDLINE]
16.

Possible protection by notoginsenoside R1 against glutamate neurotoxicity mediated by N-methyl-D-aspartate receptors composed of an NR1/NR2B subunit assembly.

Gu B, Nakamichi N, Zhang WS, Nakamura Y, Kambe Y, Fukumori R, Takuma K, Yamada K, Takarada T, Taniura H, Yoneda Y.

J Neurosci Res. 2009 Jul;87(9):2145-56. doi: 10.1002/jnr.22021.

PMID:
19224577
[PubMed - indexed for MEDLINE]
17.

Knockdown of the aryl hydrocarbon receptor attenuates excitotoxicity and enhances NMDA-induced BDNF expression in cortical neurons.

Lin CH, Chen CC, Chou CM, Wang CY, Hung CC, Chen JY, Chang HW, Chen YC, Yeh GC, Lee YH.

J Neurochem. 2009 Nov;111(3):777-89. doi: 10.1111/j.1471-4159.2009.06364.x. Epub 2009 Aug 27.

PMID:
19712055
[PubMed - indexed for MEDLINE]
18.

Involvement of the GluN2A and GluN2B subunits in synaptic and extrasynaptic N-methyl-D-aspartate receptor function and neuronal excitotoxicity.

Zhou X, Ding Q, Chen Z, Yun H, Wang H.

J Biol Chem. 2013 Aug 16;288(33):24151-9. doi: 10.1074/jbc.M113.482000. Epub 2013 Jul 9.

PMID:
23839940
[PubMed - indexed for MEDLINE]
19.

Barbiturates induce mitochondrial depolarization and potentiate excitotoxic neuronal death.

Anderson CM, Norquist BA, Vesce S, Nicholls DG, Soine WH, Duan S, Swanson RA.

J Neurosci. 2002 Nov 1;22(21):9203-9.

PMID:
12417645
[PubMed - indexed for MEDLINE]
Free Article
20.

Distinctive characteristics and functions of multiple mitochondrial Ca2+ influx mechanisms.

Pan S, Ryu SY, Sheu SS.

Sci China Life Sci. 2011 Aug;54(8):763-9. doi: 10.1007/s11427-011-4203-9. Epub 2011 Jul 24. Review.

PMID:
21786199
[PubMed - indexed for MEDLINE]
Free PMC Article

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