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Items: 1 to 20 of 186


Stimulation of in vivo nuclear transport dynamics of actin and its co-factors IQGAP1 and Rac1 in response to DNA replication stress.

Johnson MA, Sharma M, Mok MT, Henderson BR.

Biochim Biophys Acta. 2013 Oct;1833(10):2334-47. doi: 10.1016/j.bbamcr.2013.06.002. Epub 2013 Jun 13.


IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest.

Johnson M, Sharma M, Brocardo MG, Henderson BR.

Int J Biochem Cell Biol. 2011 Jan;43(1):65-73. doi: 10.1016/j.biocel.2010.09.014. Epub 2010 Sep 29.


IQGAP1 regulates Salmonella invasion through interactions with actin, Rac1, and Cdc42.

Brown MD, Bry L, Li Z, Sacks DB.

J Biol Chem. 2007 Oct 12;282(41):30265-72. Epub 2007 Aug 11.


Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact.

Noritake J, Fukata M, Sato K, Nakagawa M, Watanabe T, Izumi N, Wang S, Fukata Y, Kaibuchi K.

Mol Biol Cell. 2004 Mar;15(3):1065-76. Epub 2003 Dec 29.


Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration.

Watanabe T, Wang S, Noritake J, Sato K, Fukata M, Takefuji M, Nakagawa M, Izumi N, Akiyama T, Kaibuchi K.

Dev Cell. 2004 Dec;7(6):871-83.


IQGAP1 stimulates actin assembly through the N-WASP-Arp2/3 pathway.

Le Clainche C, Schlaepfer D, Ferrari A, Klingauf M, Grohmanova K, Veligodskiy A, Didry D, Le D, Egile C, Carlier MF, Kroschewski R.

J Biol Chem. 2007 Jan 5;282(1):426-35. Epub 2006 Nov 2.


Actin pedestal formation by enteropathogenic Escherichia coli is regulated by IQGAP1, calcium, and calmodulin.

Brown MD, Bry L, Li Z, Sacks DB.

J Biol Chem. 2008 Dec 12;283(50):35212-22. doi: 10.1074/jbc.M803477200. Epub 2008 Sep 22.


IQGAP1 interactome analysis by in vitro reconstitution and live cell 3-color FRET microscopy.

Wallrabe H, Cai Y, Sun Y, Periasamy A, Luzes R, Fang X, Kan HM, Cameron LC, Schafer DA, Bloom GS.

Cytoskeleton (Hoboken). 2013 Dec;70(12):819-36. doi: 10.1002/cm.21146. Epub 2013 Oct 16.


Active maintenance of nuclear actin by importin 9 supports transcription.

Dopie J, Skarp KP, Rajakylä EK, Tanhuanpää K, Vartiainen MK.

Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):E544-52. doi: 10.1073/pnas.1118880109. Epub 2012 Feb 9.


M3 muscarinic acetylcholine receptor dysfunction inhibits Rac1 activity and disrupts VE-cadherin/β-catenin and actin cytoskeleton interaction.

Jiao ZY, Wu J, Wen B, Zhao WZ, Du XL.

Biochem Cell Biol. 2014 Apr;92(2):137-44. doi: 10.1139/bcb-2013-0042. Epub 2014 Jan 8.


Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks.

Robison JG, Elliott J, Dixon K, Oakley GG.

J Biol Chem. 2004 Aug 13;279(33):34802-10. Epub 2004 Jun 4.


Angiopoietin-1 requires IQ domain GTPase-activating protein 1 to activate Rac1 and promote endothelial barrier defense.

David S, Ghosh CC, Mukherjee A, Parikh SM.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2643-52. doi: 10.1161/ATVBAHA.111.233189.


Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress.

Misheva M, Kaur G, Ngoei KR, Yeap YY, Ng IH, Wagstaff KM, Ng DC, Jans DA, Bogoyevitch MA.

Biochim Biophys Acta. 2014 Feb;1843(2):253-64. doi: 10.1016/j.bbamcr.2013.10.017. Epub 2013 Nov 1.


Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells.

Usatyuk PV, Gorshkova IA, He D, Zhao Y, Kalari SK, Garcia JG, Natarajan V.

J Biol Chem. 2009 May 29;284(22):15339-52. doi: 10.1074/jbc.M109.005439. Epub 2009 Apr 14.


The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migration.

Pelikan-Conchaudron A, Le Clainche C, Didry D, Carlier MF.

J Biol Chem. 2011 Oct 7;286(40):35119-28. doi: 10.1074/jbc.M111.258772. Epub 2011 Jul 5.


ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway.

Hu B, Shi B, Jarzynka MJ, Yiin JJ, D'Souza-Schorey C, Cheng SY.

Cancer Res. 2009 Feb 1;69(3):794-801. doi: 10.1158/0008-5472.CAN-08-2110. Epub 2009 Jan 20.


Nuclear RhoA signaling regulates MRTF-dependent SMC-specific transcription.

Staus DP, Weise-Cross L, Mangum KD, Medlin MD, Mangiante L, Taylor JM, Mack CP.

Am J Physiol Heart Circ Physiol. 2014 Aug 1;307(3):H379-90. doi: 10.1152/ajpheart.01002.2013. Epub 2014 Jun 6.


Increased importin-beta-dependent nuclear import of the actin modulating protein CapG promotes cell invasion.

De Corte V, Van Impe K, Bruyneel E, Boucherie C, Mareel M, Vandekerckhove J, Gettemans J.

J Cell Sci. 2004 Oct 15;117(Pt 22):5283-92. Epub 2004 Sep 28.

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