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Results: 1 to 20 of 125

1.

Loss of Otx2 in the adult retina disrupts retinal pigment epithelium function, causing photoreceptor degeneration.

Housset M, Samuel A, Ettaiche M, Bemelmans A, Béby F, Billon N, Lamonerie T.

J Neurosci. 2013 Jun 12;33(24):9890-904. doi: 10.1523/JNEUROSCI.1099-13.2013. Erratum in: J Neurosci. 2014 Apr 16;34(16):5732.

PMID:
23761884
[PubMed - indexed for MEDLINE]
Free Article
2.

Otx2 gene deletion in adult mouse retina induces rapid RPE dystrophy and slow photoreceptor degeneration.

Béby F, Housset M, Fossat N, Le Greneur C, Flamant F, Godement P, Lamonerie T.

PLoS One. 2010 Jul 21;5(7):e11673. doi: 10.1371/journal.pone.0011673.

PMID:
20657788
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina.

Omori Y, Katoh K, Sato S, Muranishi Y, Chaya T, Onishi A, Minami T, Fujikado T, Furukawa T.

PLoS One. 2011;6(5):e19685. doi: 10.1371/journal.pone.0019685. Epub 2011 May 13.

PMID:
21602925
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Otx2 ChIP-seq reveals unique and redundant functions in the mature mouse retina.

Samuel A, Housset M, Fant B, Lamonerie T.

PLoS One. 2014 Feb 18;9(2):e89110. doi: 10.1371/journal.pone.0089110. eCollection 2014.

PMID:
24558479
[PubMed - in process]
Free PMC Article
6.

Regulation of the human tyrosinase gene in retinal pigment epithelium cells: the significance of transcription factor orthodenticle homeobox 2 and its polymorphic binding site.

Reinisalo M, Putula J, Mannermaa E, Urtti A, Honkakoski P.

Mol Vis. 2012;18:38-54. Epub 2012 Jan 10.

PMID:
22259223
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression.

Westenskow P, Piccolo S, Fuhrmann S.

Development. 2009 Aug;136(15):2505-10. doi: 10.1242/dev.032136. Epub 2009 Jun 24.

PMID:
19553286
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Functional roles of Otx2 transcription factor in postnatal mouse retinal development.

Koike C, Nishida A, Ueno S, Saito H, Sanuki R, Sato S, Furukawa A, Aizawa S, Matsuo I, Suzuki N, Kondo M, Furukawa T.

Mol Cell Biol. 2007 Dec;27(23):8318-29. Epub 2007 Oct 1.

PMID:
17908793
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia.

Tolmachova T, Wavre-Shapton ST, Barnard AR, MacLaren RE, Futter CE, Seabra MC.

Invest Ophthalmol Vis Sci. 2010 Oct;51(10):4913-20. doi: 10.1167/iovs.09-4892. Epub 2010 May 5.

PMID:
20445111
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Transplantation of human fetal retinal pigment epithelium rescues photoreceptor cells from degeneration in the Royal College of Surgeons rat retina.

Little CW, Castillo B, DiLoreto DA, Cox C, Wyatt J, del Cerro C, del Cerro M.

Invest Ophthalmol Vis Sci. 1996 Jan;37(1):204-11.

PMID:
8550325
[PubMed - indexed for MEDLINE]
Free Article
11.

Efficiency of lentiviral transduction during development in normal and rd mice.

Pang J, Cheng M, Haire SE, Barker E, Planelles V, Blanks JC.

Mol Vis. 2006 Jul 11;12:756-67.

PMID:
16862069
[PubMed - indexed for MEDLINE]
Free Article
12.

Light-evoked responses of the retinal pigment epithelium: changes accompanying photoreceptor loss in the mouse.

Samuels IS, Sturgill GM, Grossman GH, Rayborn ME, Hollyfield JG, Peachey NS.

J Neurophysiol. 2010 Jul;104(1):391-402. doi: 10.1152/jn.00088.2010. Epub 2010 May 19.

PMID:
20484527
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice.

Zhao C, Yasumura D, Li X, Matthes M, Lloyd M, Nielsen G, Ahern K, Snyder M, Bok D, Dunaief JL, LaVail MM, Vollrath D.

J Clin Invest. 2011 Jan;121(1):369-83. doi: 10.1172/JCI44303. Epub 2010 Dec 6.

PMID:
21135502
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Degeneration of the mouse retina upon dysregulated activity of serum response factor.

Sandström J, Heiduschka P, Beck SC, Philippar U, Seeliger MW, Schraermeyer U, Nordheim A.

Mol Vis. 2011 Apr 29;17:1110-27.

PMID:
21552476
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors.

Emerson MM, Cepko CL.

Dev Biol. 2011 Dec 1;360(1):241-55. doi: 10.1016/j.ydbio.2011.09.012. Epub 2011 Sep 21.

PMID:
21963459
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors.

Fossat N, Le Greneur C, Béby F, Vincent S, Godement P, Chatelain G, Lamonerie T.

BMC Dev Biol. 2007 Nov 2;7:122.

PMID:
17980036
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Dorsal retinal pigment epithelium differentiates as neural retina in the microphthalmia (mi/mi) mouse.

Bumsted KM, Barnstable CJ.

Invest Ophthalmol Vis Sci. 2000 Mar;41(3):903-8.

PMID:
10711712
[PubMed - indexed for MEDLINE]
Free Article
18.

Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA).

Pang JJ, Chang B, Hawes NL, Hurd RE, Davisson MT, Li J, Noorwez SM, Malhotra R, McDowell JH, Kaushal S, Hauswirth WW, Nusinowitz S, Thompson DA, Heckenlively JR.

Mol Vis. 2005 Feb 28;11:152-62.

PMID:
15765048
[PubMed - indexed for MEDLINE]
Free Article
19.

Progressive dysfunction of the retinal pigment epithelium and retina due to increased VEGF-A levels.

Ablonczy Z, Dahrouj M, Marneros AG.

FASEB J. 2014 May;28(5):2369-79. doi: 10.1096/fj.13-248021. Epub 2014 Feb 20.

PMID:
24558195
[PubMed - indexed for MEDLINE]
20.

Protective gene expression changes elicited by an inherited defect in photoreceptor structure.

Sharma YV, Cojocaru RI, Ritter LM, Khattree N, Brooks M, Scott A, Swaroop A, Goldberg AF.

PLoS One. 2012;7(2):e31371. doi: 10.1371/journal.pone.0031371. Epub 2012 Feb 20.

PMID:
22363631
[PubMed - indexed for MEDLINE]
Free PMC Article

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