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Results: 1 to 20 of 160

1.

Reynosin protects against neuronal toxicity in dopamine-induced SH-SY5Y cells and 6-hydroxydopamine-lesioned rats as models of Parkinson's disease: Reciprocal up-regulation of E6-AP and down-regulation of α-synuclein.

Ham A, Kim DW, Kim KH, Lee SJ, Oh KB, Shin J, Mar W.

Brain Res. 2013 Aug 2;1524:54-61. doi: 10.1016/j.brainres.2013.05.036. Epub 2013 Jun 8.

PMID:
23751361
[PubMed - indexed for MEDLINE]
2.

Moracenin D from Mori Cortex radicis protects SH-SY5Y cells against dopamine-induced cell death by regulating nurr1 and α-synuclein expression.

Ham A, Lee HJ, Hong SS, Lee D, Mar W.

Phytother Res. 2012 Apr;26(4):620-4. doi: 10.1002/ptr.3592. Epub 2011 Sep 20.

PMID:
21936000
[PubMed - indexed for MEDLINE]
3.

Down-regulation of alpha-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model.

Hayashita-Kinoh H, Yamada M, Yokota T, Mizuno Y, Mochizuki H.

Biochem Biophys Res Commun. 2006 Mar 24;341(4):1088-95. Epub 2006 Jan 25.

PMID:
16460685
[PubMed - indexed for MEDLINE]
4.

Neuroprotective effects of SCM198 on 6-hydroxydopamine-induced behavioral deficit in rats and cytotoxicity in neuronal SH-SY5Y cells.

Shi XR, Hong ZY, Liu HR, Zhang YC, Zhu YZ.

Neurochem Int. 2011 Jul;58(8):851-60. doi: 10.1016/j.neuint.2010.11.007. Epub 2010 Nov 18.

PMID:
21093517
[PubMed - indexed for MEDLINE]
5.

Lithium protects against oxidative stress-mediated cell death in α-synuclein-overexpressing in vitro and in vivo models of Parkinson's disease.

Kim YH, Rane A, Lussier S, Andersen JK.

J Neurosci Res. 2011 Oct;89(10):1666-75. doi: 10.1002/jnr.22700. Epub 2011 Jun 24.

PMID:
21710541
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Vasoactive intestinal peptide (VIP) prevents neurotoxicity in neuronal cultures: relevance to neuroprotection in Parkinson's disease.

Offen D, Sherki Y, Melamed E, Fridkin M, Brenneman DE, Gozes I.

Brain Res. 2000 Jan 31;854(1-2):257-62.

PMID:
10784133
[PubMed - indexed for MEDLINE]
7.

Alpha-synuclein protects cerebellar granule neurons against 6-hydroxydopamine-induced death.

Monti B, Polazzi E, Batti L, Crochemore C, Virgili M, Contestabile A.

J Neurochem. 2007 Oct;103(2):518-30. Epub 2007 Jul 17.

PMID:
17635667
[PubMed - indexed for MEDLINE]
8.

Parkin disrupts the alpha-synuclein/dopamine transporter interaction: consequences toward dopamine-induced toxicity.

Moszczynska A, Saleh J, Zhang H, Vukusic B, Lee FJ, Liu F.

J Mol Neurosci. 2007;32(3):217-27.

PMID:
17873367
[PubMed - indexed for MEDLINE]
9.

Neuroprotective and neurorescue effect of black tea extract in 6-hydroxydopamine-lesioned rat model of Parkinson's disease.

Chaturvedi RK, Shukla S, Seth K, Chauhan S, Sinha C, Shukla Y, Agrawal AK.

Neurobiol Dis. 2006 May;22(2):421-34. Epub 2006 Feb 9.

PMID:
16480889
[PubMed - indexed for MEDLINE]
10.

α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment.

George S, Mok SS, Nurjono M, Ayton S, Finkelstein DI, Masters CL, Li QX, Culvenor JG.

J Mol Neurosci. 2010 Oct;42(2):243-54. doi: 10.1007/s12031-010-9378-1. Epub 2010 May 13.

PMID:
20464527
[PubMed - indexed for MEDLINE]
11.

Regulatory effects of costunolide on dopamine metabolism-associated genes inhibit dopamine-induced apoptosis in human dopaminergic SH-SY5Y cells.

Ham A, Lee SJ, Shin J, Kim KH, Mar W.

Neurosci Lett. 2012 Jan 24;507(2):101-5. doi: 10.1016/j.neulet.2011.10.037. Epub 2011 Oct 21.

PMID:
22040670
[PubMed - indexed for MEDLINE]
12.

Methylparaben protects 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells and improved behavioral impairments in mouse model of Parkinson's disease.

Kopalli SR, Noh SJ, Koppula S, Suh YH.

Neurotoxicology. 2013 Jan;34:25-32. doi: 10.1016/j.neuro.2012.10.003. Epub 2012 Oct 12.

PMID:
23068419
[PubMed - indexed for MEDLINE]
13.

Rosiglitazone, a PPAR-γ agonist, protects against striatal dopaminergic neurodegeneration induced by 6-OHDA lesions in the substantia nigra of rats.

Lee EY, Lee JE, Park JH, Shin IC, Koh HC.

Toxicol Lett. 2012 Sep 18;213(3):332-44. doi: 10.1016/j.toxlet.2012.07.016. Epub 2012 Jul 27.

PMID:
22842585
[PubMed - indexed for MEDLINE]
14.

The ubiquitin ligase E6-AP promotes degradation of alpha-synuclein.

Mulherkar SA, Sharma J, Jana NR.

J Neurochem. 2009 Sep;110(6):1955-64. doi: 10.1111/j.1471-4159.2009.06293.x. Epub 2009 Jul 23.

PMID:
19645749
[PubMed - indexed for MEDLINE]
15.

GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson's disease.

Decressac M, Ulusoy A, Mattsson B, Georgievska B, Romero-Ramos M, Kirik D, Björklund A.

Brain. 2011 Aug;134(Pt 8):2302-11. doi: 10.1093/brain/awr149. Epub 2011 Jun 28.

PMID:
21712347
[PubMed - indexed for MEDLINE]
Free Article
16.

Neuroprotective effects of erythropoietin on 6-hydroxydopamine-treated ventral mesencephalic dopamine-rich cultures.

Ganser C, Papazoglou A, Just L, Nikkhah G.

Exp Cell Res. 2010 Mar 10;316(5):737-46. doi: 10.1016/j.yexcr.2010.01.001. Epub 2010 Jan 11.

PMID:
20060824
[PubMed - indexed for MEDLINE]
17.

The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors--relevance to Parkinson's disease.

Marwarha G, Rhen T, Schommer T, Ghribi O.

J Neurochem. 2011 Dec;119(5):1119-36. doi: 10.1111/j.1471-4159.2011.07497.x. Epub 2011 Oct 24.

PMID:
21951066
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons.

Sharma SK, Ebadi M.

Antioxid Redox Signal. 2003 Jun;5(3):251-64.

PMID:
12880480
[PubMed - indexed for MEDLINE]
19.

RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport.

Fountaine TM, Wade-Martins R.

J Neurosci Res. 2007 Feb 1;85(2):351-63.

PMID:
17131421
[PubMed - indexed for MEDLINE]
20.

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease.

Lo Bianco C, Schneider BL, Bauer M, Sajadi A, Brice A, Iwatsubo T, Aebischer P.

Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17510-5. Epub 2004 Dec 2.

PMID:
15576511
[PubMed - indexed for MEDLINE]
Free PMC Article

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