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Results: 1 to 20 of 147

1.

Discrete effects of A57G-myosin essential light chain mutation associated with familial hypertrophic cardiomyopathy.

Kazmierczak K, Paulino EC, Huang W, Muthu P, Liang J, Yuan CC, Rojas AI, Hare JM, Szczesna-Cordary D.

Am J Physiol Heart Circ Physiol. 2013 Aug 15;305(4):H575-89. doi: 10.1152/ajpheart.00107.2013. Epub 2013 Jun 7.

PMID:
23748425
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice.

Abraham TP, Jones M, Kazmierczak K, Liang HY, Pinheiro AC, Wagg CS, Lopaschuk GD, Szczesna-Cordary D.

Cardiovasc Res. 2009 Apr 1;82(1):84-92. doi: 10.1093/cvr/cvp016. Epub 2009 Jan 15.

PMID:
19150977
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Structural and functional aspects of the myosin essential light chain in cardiac muscle contraction.

Muthu P, Wang L, Yuan CC, Kazmierczak K, Huang W, Hernandez OM, Kawai M, Irving TC, Szczesna-Cordary D.

FASEB J. 2011 Dec;25(12):4394-405. doi: 10.1096/fj.11-191973. Epub 2011 Sep 1.

PMID:
21885653
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The E22K mutation of myosin RLC that causes familial hypertrophic cardiomyopathy increases calcium sensitivity of force and ATPase in transgenic mice.

Szczesna-Cordary D, Guzman G, Zhao J, Hernandez O, Wei J, Diaz-Perez Z.

J Cell Sci. 2005 Aug 15;118(Pt 16):3675-83. Epub 2005 Aug 2.

PMID:
16076902
[PubMed - indexed for MEDLINE]
Free Article
5.

Myosin regulatory light chain mutation found in hypertrophic cardiomyopathy patients increases isometric force production in transgenic mice.

Kazmierczak K, Muthu P, Huang W, Jones M, Wang Y, Szczesna-Cordary D.

Biochem J. 2012 Feb 15;442(1):95-103. doi: 10.1042/BJ20111145.

PMID:
22091967
[PubMed - indexed for MEDLINE]
Free Article
6.

E22K mutation of RLC that causes familial hypertrophic cardiomyopathy in heterozygous mouse myocardium: effect on cross-bridge kinetics.

Dumka D, Talent J, Akopova I, Guzman G, Szczesna-Cordary D, Borejdo J.

Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2098-106. Epub 2006 Jun 2.

PMID:
16751284
[PubMed - indexed for MEDLINE]
Free Article
7.

Deletion of 1-43 amino acids in cardiac myosin essential light chain blunts length dependency of Ca(2+) sensitivity and cross-bridge detachment kinetics.

Michael JJ, Gollapudi SK, Ford SJ, Kazmierczak K, Szczesna-Cordary D, Chandra M.

Am J Physiol Heart Circ Physiol. 2013 Jan 15;304(2):H253-9. doi: 10.1152/ajpheart.00572.2012. Epub 2012 Nov 9.

PMID:
23144314
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Malignant familial hypertrophic cardiomyopathy D166V mutation in the ventricular myosin regulatory light chain causes profound effects in skinned and intact papillary muscle fibers from transgenic mice.

Kerrick WG, Kazmierczak K, Xu Y, Wang Y, Szczesna-Cordary D.

FASEB J. 2009 Mar;23(3):855-65. doi: 10.1096/fj.08-118182. Epub 2008 Nov 5.

PMID:
18987303
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

In vitro rescue study of a malignant familial hypertrophic cardiomyopathy phenotype by pseudo-phosphorylation of myosin regulatory light chain.

Muthu P, Liang J, Schmidt W, Moore JR, Szczesna-Cordary D.

Arch Biochem Biophys. 2014 Jun 15;552-553:29-39. doi: 10.1016/j.abb.2013.12.011. Epub 2013 Dec 26.

PMID:
24374283
[PubMed - indexed for MEDLINE]
10.

Remodeling of the heart in hypertrophy in animal models with myosin essential light chain mutations.

Kazmierczak K, Yuan CC, Liang J, Huang W, Rojas AI, Szczesna-Cordary D.

Front Physiol. 2014 Sep 22;5:353. doi: 10.3389/fphys.2014.00353. eCollection 2014.

PMID:
25295008
[PubMed]
Free PMC Article
11.

Cross-bridge kinetics in myofibrils containing familial hypertrophic cardiomyopathy R58Q mutation in the regulatory light chain of myosin.

Mettikolla P, Calander N, Luchowski R, Gryczynski I, Gryczynski Z, Zhao J, Szczesna-Cordary D, Borejdo J.

J Theor Biol. 2011 Sep 7;284(1):71-81. doi: 10.1016/j.jtbi.2011.06.014. Epub 2011 Jun 24.

PMID:
21723297
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The effect of myosin RLC phosphorylation in normal and cardiomyopathic mouse hearts.

Muthu P, Kazmierczak K, Jones M, Szczesna-Cordary D.

J Cell Mol Med. 2012 Apr;16(4):911-9. doi: 10.1111/j.1582-4934.2011.01371.x.

PMID:
21696541
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Characterizations of myosin essential light chain's N-terminal truncation mutant Δ43 in transgenic mouse papillary muscles by using tension transients in response to sinusoidal length alterations.

Wang L, Muthu P, Szczesna-Cordary D, Kawai M.

J Muscle Res Cell Motil. 2013 May;34(2):93-105. doi: 10.1007/s10974-013-9337-x. Epub 2013 Feb 9.

PMID:
23397074
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis.

Sheehan KA, Arteaga GM, Hinken AC, Dias FA, Ribeiro C, Wieczorek DF, Solaro RJ, Wolska BM.

J Mol Cell Cardiol. 2011 Mar;50(3):442-50. doi: 10.1016/j.yjmcc.2010.10.032. Epub 2010 Nov 1.

PMID:
21047515
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

F110I and R278C troponin T mutations that cause familial hypertrophic cardiomyopathy affect muscle contraction in transgenic mice and reconstituted human cardiac fibers.

Hernandez OM, Szczesna-Cordary D, Knollmann BC, Miller T, Bell M, Zhao J, Sirenko SG, Diaz Z, Guzman G, Xu Y, Wang Y, Kerrick WG, Potter JD.

J Biol Chem. 2005 Nov 4;280(44):37183-94. Epub 2005 Aug 22.

PMID:
16115869
[PubMed - indexed for MEDLINE]
Free Article
16.

The role of the N-terminus of the myosin essential light chain in cardiac muscle contraction.

Kazmierczak K, Xu Y, Jones M, Guzman G, Hernandez OM, Kerrick WG, Szczesna-Cordary D.

J Mol Biol. 2009 Apr 3;387(3):706-25. doi: 10.1016/j.jmb.2009.02.006. Epub 2009 Feb 11.

PMID:
19361417
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Myosin regulatory light chain E22K mutation results in decreased cardiac intracellular calcium and force transients.

Szczesna-Cordary D, Jones M, Moore JR, Watt J, Kerrick WG, Xu Y, Wang Y, Wagg C, Lopaschuk GD.

FASEB J. 2007 Dec;21(14):3974-85. Epub 2007 Jul 2.

PMID:
17606808
[PubMed - indexed for MEDLINE]
Free Article
18.

Single molecule kinetics in the familial hypertrophic cardiomyopathy D166V mutant mouse heart.

Muthu P, Mettikolla P, Calander N, Luchowski R, Gryczynski I, Gryczynski Z, Szczesna-Cordary D, Borejdo J.

J Mol Cell Cardiol. 2010 May;48(5):989-98. doi: 10.1016/j.yjmcc.2009.11.004. Epub 2009 Nov 13.

PMID:
19914255
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Lys184 deletion in troponin I impairs relaxation kinetics and induces hypercontractility in murine cardiac myofibrils.

Iorga B, Blaudeck N, Solzin J, Neulen A, Stehle I, Lopez Davila AJ, Pfitzer G, Stehle R.

Cardiovasc Res. 2008 Mar 1;77(4):676-86. Epub 2007 Dec 20.

PMID:
18096573
[PubMed - indexed for MEDLINE]
Free Article
20.

Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling.

Knollmann BC, Kirchhof P, Sirenko SG, Degen H, Greene AE, Schober T, Mackow JC, Fabritz L, Potter JD, Morad M.

Circ Res. 2003 Mar 7;92(4):428-36. Epub 2003 Feb 6.

PMID:
12600890
[PubMed - indexed for MEDLINE]
Free Article

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