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CD4+ CD31+ recent thymic emigrants in CHD7 haploinsufficiency (CHARGE syndrome): a case.

Assing K, Nielsen C, Kirchhoff M, Madsen HO, Ryder LP, Fisker N.

Hum Immunol. 2013 Sep;74(9):1047-50. doi: 10.1016/j.humimm.2013.06.002. Epub 2013 Jun 7.


The CD4(+)CD8(+) and CD4(+) subsets of FOXP3(+) thymocytes differ in their response to growth factor deprivation or stimulation.

Lehtoviita A, Rossi LH, Kekäläinen E, Sairanen H, Arstila TP.

Scand J Immunol. 2009 Oct;70(4):377-83. doi: 10.1111/j.1365-3083.2009.02307.x.


Prevalence of newly generated naive regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis.

Haas J, Fritzsching B, Trübswetter P, Korporal M, Milkova L, Fritz B, Vobis D, Krammer PH, Suri-Payer E, Wildemann B.

J Immunol. 2007 Jul 15;179(2):1322-30.


Flow cytometric analysis of TCR Vβ repertoire in patients with 22q11.2 deletion syndrome.

McLean-Tooke A, Barge D, Spickett GP, Gennery AR.

Scand J Immunol. 2011 Jun;73(6):577-85. doi: 10.1111/j.1365-3083.2011.02527.x.


CD31 (PECAM-1) is a marker of recent thymic emigrants among CD4+ T-cells, but not CD8+ T-cells or gammadelta T-cells, in HIV patients responding to ART.

Tanaskovic S, Fernandez S, Price P, Lee S, French MA.

Immunol Cell Biol. 2010 Mar-Apr;88(3):321-7. doi: 10.1038/icb.2009.108. Epub 2010 Jan 12.


Correlation between recent thymic emigrants and CD31+ (PECAM-1) CD4+ T cells in normal individuals during aging and in lymphopenic children.

Junge S, Kloeckener-Gruissem B, Zufferey R, Keisker A, Salgo B, Fauchere JC, Scherer F, Shalaby T, Grotzer M, Siler U, Seger R, Güngör T.

Eur J Immunol. 2007 Nov;37(11):3270-80.


Recent thymic origin, differentiation, and turnover of regulatory T cells.

Mabarrack NH, Turner NL, Mayrhofer G.

J Leukoc Biol. 2008 Nov;84(5):1287-97. doi: 10.1189/jlb.0308201. Epub 2008 Aug 5.


Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection.

Coutinho A, Caramalho I, Seixas E, Demengeot J.

Curr Top Microbiol Immunol. 2005;293:43-71. Review.


Thymopoiesis, regulatory T cells, and TCRVbeta expression in thymoma with and without myasthenia gravis, and modulatory effects of steroid therapy.

Fattorossi A, Battaglia A, Buzzonetti A, Minicuci G, Riso R, Peri L, Scambia G, Evoli A.

J Clin Immunol. 2008 Mar;28(2):194-206. Epub 2007 Nov 14.


Development of mouse CD4(+)CD25(+)Foxp3(+) regulatory T cells in xenogeneic pig thymic grafts.

Zhang B, Zhang A, Qu Y, Liu J, Niu Z, Zhao Y.

Transpl Immunol. 2009 Jan;20(3):180-5. doi: 10.1016/j.trim.2008.09.006. Epub 2008 Oct 7.


Thymus transplantation restores the repertoires of forkhead box protein 3 (FoxP3)+ and FoxP3- T cells in complete DiGeorge anomaly.

Chinn IK, Milner JD, Scheinberg P, Douek DC, Markert ML.

Clin Exp Immunol. 2013 Jul;173(1):140-9. doi: 10.1111/cei.12088.


Abnormalities in the T and NK lymphocyte phenotype in patients with Nijmegen breakage syndrome.

Michałkiewicz J, Barth C, Chrzanowska K, Gregorek H, Syczewska M, Weemaes CM, Madaliński K, Stachowski J; D. DZIERZANOWSKA.

Clin Exp Immunol. 2003 Dec;134(3):482-90.


Low thymic output in the 22q11.2 deletion syndrome measured by CCR9+CD45RA+ T cell counts and T cell receptor rearrangement excision circles.

Lima K, Abrahamsen TG, Foelling I, Natvig S, Ryder LP, Olaussen RW.

Clin Exp Immunol. 2010 Jul 1;161(1):98-107. doi: 10.1111/j.1365-2249.2010.04152.x. Epub 2010 May 10.


Cell generation within human thymic subsets defined by selective expression of CD45 (T200) isoforms.

Egerton M, Pruski E, Pilarski LM.

Hum Immunol. 1990 Apr;27(4):333-47.


Identification of three novel mutations in the CHD7 gene in patients with clinical signs of typical or atypical CHARGE syndrome.

Michelucci A, Ghirri P, Iacopetti P, Conidi ME, Fogli A, Baldinotti F, Lunardi S, Forli F, Moscuzza F, Berrettini S, Boldrini A, Simi P, Pellegrini S.

Int J Pediatr Otorhinolaryngol. 2010 Dec;74(12):1441-4. doi: 10.1016/j.ijporl.2010.09.006. Epub 2010 Oct 12.


T-cell homeostasis in humans with thymic hypoplasia due to chromosome 22q11.2 deletion syndrome.

Piliero LM, Sanford AN, McDonald-McGinn DM, Zackai EH, Sullivan KE.

Blood. 2004 Feb 1;103(3):1020-5. Epub 2003 Oct 2.


Differentiation of ICOS+ and ICOS- recent thymic emigrant regulatory T cells (RTE T regs) during normal pregnancy, pre-eclampsia and HELLP syndrome.

Wagner MI, Jöst M, Spratte J, Schaier M, Mahnke K, Meuer S, Zeier M, Steinborn A.

Clin Exp Immunol. 2016 Jan;183(1):129-42. doi: 10.1111/cei.12693. Epub 2015 Oct 12.


Excessive conversion and impaired thymic output contribute to disturbed regulatory T-cell homeostasis in AIDS patients with low CD4 cell counts.

Zhou H, Zhao H, Hao Y, Song C, Han J, Zhang J, Gao G, Han N, Yang D, Li Y, Zhang F, Zeng H.

AIDS. 2013 Apr 24;27(7):1059-69. doi: 10.1097/QAD.0b013e32835e2b99.

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