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Identification of potential anticancer compounds from Oplopanax horridus.

Wang CZ, Zhang Z, Huang WH, Du GJ, Wen XD, Calway T, Yu C, Nass R, Zhao J, Du W, Li SP, Yuan CS.

Phytomedicine. 2013 Aug 15;20(11):999-1006. doi: 10.1016/j.phymed.2013.04.013. Epub 2013 Jun 5.


High performance liquid chromatographic analysis and anticancer potential of Oplopanax horridus: comparison of stem and berry extracts.

Wang CZ, Aung HH, Mehendale SR, Shoyama Y, Yuan CS.

Fitoterapia. 2010 Mar;81(2):132-9. doi: 10.1016/j.fitote.2009.08.003. Epub 2009 Aug 14.


Chemopreventive effects of oplopantriol A, a novel compound isolated from Oplopanax horridus, on colorectal cancer.

Zhang Z, Yu C, Zhang CF, Wu XH, Wen XD, Anderson S, Du W, Huang WH, Li SP, Wang CZ, Yuan CS.

Nutrients. 2014 Jul 18;6(7):2668-80. doi: 10.3390/nu6072668.


Hydrophobic constituents and their potential anticancer activities from Devil's Club (Oplopanax horridus Miq.).

Sun S, Du GJ, Qi LW, Williams S, Wang CZ, Yuan CS.

J Ethnopharmacol. 2010 Oct 28;132(1):280-5. doi: 10.1016/j.jep.2010.08.026. Epub 2010 Aug 17.


Effects of Oplopanax horridus on human colorectal cancer cells.

Li XL, Sun S, Du GJ, Qi LW, Williams S, Wang CZ, Yuan CS.

Anticancer Res. 2010 Feb;30(2):295-302.


Improving anticancer activities of Oplopanax horridus root bark extract by removing water-soluble components.

Sun S, Li XL, Wang CZ, Williams S, Yuan CS.

Phytother Res. 2010 Aug;24(8):1166-74. doi: 10.1002/ptr.3061.


Antiproliferation activity of Devil's club (Oplopanax horridus) and anticancer agents on human pancreatic cancer multicellular spheroids.

Tai J, Cheung SS, Ou D, Warnock GL, Hasman D.

Phytomedicine. 2014 Mar 15;21(4):506-14. doi: 10.1016/j.phymed.2013.10.003. Epub 2013 Nov 9.


Anticancer activities of polyynes from the root bark of Oplopanax horridus and their acetylated derivatives.

Huang WH, Shao L, Wang CZ, Yuan CS, Zhou HH.

Molecules. 2014 May 14;19(5):6142-62. doi: 10.3390/molecules19056142. Erratum in: Molecules. 2015;20(4):5438-9.


Human ovarian cancer multicellular spheroids: a model for testing antiproliferation activity of Devil's club (Oplopanax horridus) and anticancer agents.

Tai J, Cheung SS, Hasman D.

Planta Med. 2014 Jun;80(8-9):662-70. doi: 10.1055/s-0034-1368506. Epub 2014 Jun 12.


Chemical and pharmacological studies of Oplopanax horridus, a North American botanical.

Calway T, Du GJ, Wang CZ, Huang WH, Zhao J, Li SP, Yuan CS.

J Nat Med. 2012 Apr;66(2):249-56. doi: 10.1007/s11418-011-0602-2. Epub 2011 Nov 20. Review.


Spica prunellae promotes cancer cell apoptosis, inhibits cell proliferation and tumor angiogenesis in a mouse model of colorectal cancer via suppression of stat3 pathway.

Lin W, Zheng L, Zhuang Q, Zhao J, Cao Z, Zeng J, Lin S, Xu W, Peng J.

BMC Complement Altern Med. 2013 Jun 24;13:144. doi: 10.1186/1472-6882-13-144.


Inhibition of human ovarian cancer cell lines by devil's club Oplopanax horridus.

Tai J, Cheung S, Chan E, Hasman D.

J Ethnopharmacol. 2010 Feb 3;127(2):478-85. doi: 10.1016/j.jep.2009.10.010. Epub 2009 Oct 14.


Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation.

Duangmano S, Sae-Lim P, Suksamrarn A, Domann FE, Patmasiriwat P.

BMC Complement Altern Med. 2012 Oct 12;12:185. doi: 10.1186/1472-6882-12-185.


A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway.

Cao W, Li XQ, Wang X, Fan HT, Zhang XN, Hou Y, Liu SB, Mei QB.

Phytomedicine. 2010 Jul;17(8-9):598-605. doi: 10.1016/j.phymed.2009.12.014. Epub 2010 Jan 25.


A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-β signaling pathways.

Jia L, Jin H, Zhou J, Chen L, Lu Y, Ming Y, Yu Y.

BMC Complement Altern Med. 2013 Feb 15;13:33. doi: 10.1186/1472-6882-13-33.


Isolation and chemopreventive evaluation of novel naphthoquinone compounds from Alkanna tinctoria.

Tung NH, Du GJ, Yuan CS, Shoyama Y, Wang CZ.

Anticancer Drugs. 2013 Nov;24(10):1058-68. doi: 10.1097/CAD.0000000000000017.


Components of rhizome extract of Cnidium officinale Makino and their in vitro biological effects.

Bae KE, Choi YW, Kim ST, Kim YK.

Molecules. 2011 Oct 21;16(10):8833-47. doi: 10.3390/molecules16108833.


Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway.

Wang CZ, Calway TD, Wen XD, Smith J, Yu C, Wang Y, Mehendale SR, Yuan CS.

Int J Oncol. 2013 Mar;42(3):1018-26. doi: 10.3892/ijo.2013.1777. Epub 2013 Jan 16.


In vitro and in vivo anticancer effects of American ginseng berry: exploring representative compounds.

Xie JT, Wang CZ, Zhang B, Mehendale SR, Li XL, Sun S, Han AH, Du W, He TC, Yuan CS.

Biol Pharm Bull. 2009 Sep;32(9):1552-8.


The antitumor natural compound falcarindiol promotes cancer cell death by inducing endoplasmic reticulum stress.

Jin HR, Zhao J, Zhang Z, Liao Y, Wang CZ, Huang WH, Li SP, He TC, Yuan CS, Du W.

Cell Death Dis. 2012 Aug 23;3:e376. doi: 10.1038/cddis.2012.122.

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