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Results: 1 to 20 of 102

Similar articles for PubMed (Select 23746060)

1.

Recent advances in the synthesis of tubulysins.

Xiangming X, Friestad GK, Lei Y.

Mini Rev Med Chem. 2013 Oct;13(11):1572-8. Review.

PMID:
23746060
2.

Synthesis and biological evaluation of tubulysin D analogs related to stereoisomers of tubuvaline.

Shibue T, Okamoto I, Morita N, Morita H, Hirasawa Y, Hosoya T, Tamura O.

Bioorg Med Chem Lett. 2011 Jan 1;21(1):431-4. doi: 10.1016/j.bmcl.2010.10.118. Epub 2010 Oct 30.

PMID:
21106374
3.

Acid mediated formation of an N-acyliminium ion from tubulysins: a new methodology for the synthesis of natural tubulysins and their analogs.

Vlahov IR, Wang Y, Vetzel M, Hahn S, Kleindl PJ, Reddy JA, Leamon CP.

Bioorg Med Chem Lett. 2011 Nov 15;21(22):6778-81. doi: 10.1016/j.bmcl.2011.09.041. Epub 2011 Sep 17.

PMID:
21974954
4.

Total syntheses of tubulysins.

Shibue T, Hirai T, Okamoto I, Morita N, Masu H, Azumaya I, Tamura O.

Chemistry. 2010 Oct 11;16(38):11678-88. doi: 10.1002/chem.201000963. Epub 2010 Aug 23.

PMID:
20734394
5.

Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents.

Patil SA, Patil R, Miller DD.

Future Med Chem. 2012 Oct;4(16):2085-115. doi: 10.4155/fmc.12.141. Review.

PMID:
23157240
6.

Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents.

Abuhaie CM, Bîcu E, Rigo B, Gautret P, Belei D, Farce A, Dubois J, Ghinet A.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):147-52. doi: 10.1016/j.bmcl.2012.10.135. Epub 2012 Nov 8.

PMID:
23200248
7.

3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerization.

Kamal A, Sultana F, Ramaiah MJ, Srikanth YV, Viswanath A, Kishor C, Sharma P, Pushpavalli SN, Addlagatta A, Pal-Bhadra M.

ChemMedChem. 2012 Feb 6;7(2):292-300. doi: 10.1002/cmdc.201100511. Epub 2012 Jan 12.

PMID:
22241597
8.

Structure-activity and high-content imaging analyses of novel tubulysins.

Wang Z, McPherson PA, Raccor BS, Balachandran R, Zhu G, Day BW, Vogt A, Wipf P.

Chem Biol Drug Des. 2007 Aug;70(2):75-86.

PMID:
17683369
9.

Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment.

Yamashita A, Norton EB, Kaplan JA, Niu C, Loganzo F, Hernandez R, Beyer CF, Annable T, Musto S, Discafani C, Zask A, Ayral-Kaloustian S.

Bioorg Med Chem Lett. 2004 Nov 1;14(21):5317-22.

PMID:
15454219
10.

Synthesis and SAR of C12-C13-oxazoline derivatives of epothilone A.

Pfeiffer B, Hauenstein K, Merz P, Gertsch J, Altmann KH.

Bioorg Med Chem Lett. 2009 Jul 15;19(14):3760-3. doi: 10.1016/j.bmcl.2009.04.112. Epub 2009 May 3.

PMID:
19433359
11.

Synthesis, molecular modeling and biological evaluation of guanidine derivatives as novel antitubulin agents.

Qian Y, Zhang HJ, Lv PC, Zhu HL.

Bioorg Med Chem. 2010 Dec 1;18(23):8218-25. doi: 10.1016/j.bmc.2010.10.008. Epub 2010 Oct 29.

PMID:
21036623
12.

[Progress in the study of tubulin inhibitors].

Shang H, Pan L, Yang S, Chen H, Cheng MS.

Yao Xue Xue Bao. 2010 Sep;45(9):1078-88. Review. Chinese.

PMID:
21351562
13.

Efforts toward the total synthesis of tubulysins: new hopes for a more effective targeted drug delivery to tumors.

Neri D, Fossati G, Zanda M.

ChemMedChem. 2006 Feb;1(2):175-80. Review. No abstract available.

PMID:
16892348
14.

2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.

Chuang HY, Chang JY, Lai MJ, Kuo CC, Lee HY, Hsieh HP, Chen YJ, Chen LT, Pan WY, Liou JP.

ChemMedChem. 2011 Mar 7;6(3):450-6. doi: 10.1002/cmdc.201000479. Epub 2011 Jan 4.

PMID:
21360819
15.

Simplified pretubulysin derivatives and their biological effects on cancer cells.

Kubisch R, von Gamm M, Braig S, Ullrich A, Burkhart JL, Colling L, Hermann J, Scherer O, Müller R, Werz O, Kazmaier U, Vollmar AM.

J Nat Prod. 2014 Mar 28;77(3):536-42. doi: 10.1021/np4008014. Epub 2014 Jan 17.

PMID:
24437936
16.

Design, synthesis and biological studies of novel tubulin inhibitors.

Sun Y, Pandit B, Chettiar SN, Etter JP, Lewis A, Johnsamuel J, Li PK.

Bioorg Med Chem Lett. 2013 Aug 1;23(15):4465-8. doi: 10.1016/j.bmcl.2013.04.078. Epub 2013 May 7.

PMID:
23790539
17.

Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.

Ouyang X, Chen X, Piatnitski EL, Kiselyov AS, He HY, Mao Y, Pattaropong V, Yu Y, Kim KH, Kincaid J, Smith L 2nd, Wong WC, Lee SP, Milligan DL, Malikzay A, Fleming J, Gerlak J, Deevi D, Doody JF, Chiang HH, Patel SN, Wang Y, Rolser RL, Kussie P, Labelle M, Tuma MC.

Bioorg Med Chem Lett. 2005 Dec 1;15(23):5154-9. Epub 2005 Sep 28.

PMID:
16198562
18.

Developments of combretastatin A-4 derivatives as anticancer agents.

Shan Y, Zhang J, Liu Z, Wang M, Dong Y.

Curr Med Chem. 2011;18(4):523-38. Review.

PMID:
21143124
19.

Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation.

Lesma G, Sacchetti A, Bai R, Basso G, Bortolozzi R, Hamel E, Silvani A, Vaiana N, Viola G.

Mol Divers. 2014 May;18(2):357-73. doi: 10.1007/s11030-014-9507-9. Epub 2014 Feb 6.

20.

Synthesis, biological evaluation, and molecular modeling of cinnamic acyl sulfonamide derivatives as novel antitubulin agents.

Luo Y, Qiu KM, Lu X, Liu K, Fu J, Zhu HL.

Bioorg Med Chem. 2011 Aug 15;19(16):4730-8. doi: 10.1016/j.bmc.2011.06.088. Epub 2011 Jul 7.

PMID:
21783370
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