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Results: 1 to 20 of 184

1.

Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice.

Díaz V, Gammella E, Recalcati S, Santambrogio P, Naldi AM, Vogel J, Gassmann M, Cairo G.

Hepatology. 2013 Dec;58(6):2122-32. doi: 10.1002/hep.26550. Epub 2013 Oct 21.

PMID:
23744538
[PubMed - indexed for MEDLINE]
2.

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.

Meynard D, Vaja V, Sun CC, Corradini E, Chen S, López-Otín C, Grgurevic L, Hong CC, Stirnberg M, Gütschow M, Vukicevic S, Babitt JL, Lin HY.

Blood. 2011 Jul 21;118(3):747-56. doi: 10.1182/blood-2011-04-348698. Epub 2011 May 26.

PMID:
21622652
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes.

Ikeda Y, Tajima S, Izawa-Ishizawa Y, Kihira Y, Ishizawa K, Tomita S, Tsuchiya K, Tamaki T.

PLoS One. 2012;7(7):e40465. doi: 10.1371/journal.pone.0040465. Epub 2012 Jul 11.

PMID:
22792339
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression.

Frazer DM, Wilkins SJ, Darshan D, Badrick AC, McLaren GD, Anderson GJ.

Br J Haematol. 2012 Jun;157(5):615-26. doi: 10.1111/j.1365-2141.2012.09104.x. Epub 2012 Mar 26.

PMID:
22449175
[PubMed - indexed for MEDLINE]
5.

Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.

Finberg KE, Whittlesey RL, Fleming MD, Andrews NC.

Blood. 2010 May 6;115(18):3817-26. doi: 10.1182/blood-2009-05-224808. Epub 2010 Mar 3.

PMID:
20200349
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice.

Corradini E, Meynard D, Wu Q, Chen S, Ventura P, Pietrangelo A, Babitt JL.

Hepatology. 2011 Jul;54(1):273-84. doi: 10.1002/hep.24359.

PMID:
21488083
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression.

Harrison-Findik DD, Schafer D, Klein E, Timchenko NA, Kulaksiz H, Clemens D, Fein E, Andriopoulos B, Pantopoulos K, Gollan J.

J Biol Chem. 2006 Aug 11;281(32):22974-82. Epub 2006 May 31.

PMID:
16737972
[PubMed - indexed for MEDLINE]
Free Article
8.

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.

Gardenghi S, Marongiu MF, Ramos P, Guy E, Breda L, Chadburn A, Liu Y, Amariglio N, Rechavi G, Rachmilewitz EA, Breuer W, Cabantchik ZI, Wrighting DM, Andrews NC, de Sousa M, Giardina PJ, Grady RW, Rivella S.

Blood. 2007 Jun 1;109(11):5027-35. Epub 2007 Feb 13.

PMID:
17299088
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis.

Vokurka M, Krijt J, Sulc K, Necas E.

Physiol Res. 2006;55(6):667-74.

PMID:
16497104
[PubMed - indexed for MEDLINE]
Free Article
10.

Effect of erythropoietin on hepcidin expression in hemojuvelin-mutant mice.

Krijt J, Jonásová A, Neuwirtová R, Necas E.

Blood Cells Mol Dis. 2010 Apr 15;44(4):257-61. doi: 10.1016/j.bcmd.2010.02.012. Epub 2010 Mar 12.

PMID:
20219396
[PubMed - indexed for MEDLINE]
11.

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice.

Corradini E, Schmidt PJ, Meynard D, Garuti C, Montosi G, Chen S, Vukicevic S, Pietrangelo A, Lin HY, Babitt JL.

Gastroenterology. 2010 Nov;139(5):1721-9. doi: 10.1053/j.gastro.2010.07.044. Epub 2010 Aug 1.

PMID:
20682319
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis.

Ryan JD, Ryan E, Fabre A, Lawless MW, Crowe J.

Hepatology. 2010 Oct;52(4):1266-73. doi: 10.1002/hep.23814.

PMID:
20658468
[PubMed - indexed for MEDLINE]
13.

The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.

Zhang AS, Gao J, Koeberl DD, Enns CA.

J Biol Chem. 2010 May 28;285(22):16416-23. doi: 10.1074/jbc.M110.109488. Epub 2010 Apr 2.

PMID:
20363739
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis.

Mastrogiannaki M, Matak P, Mathieu JR, Delga S, Mayeux P, Vaulont S, Peyssonnaux C.

Haematologica. 2012 Jun;97(6):827-34. doi: 10.3324/haematol.2011.056119. Epub 2011 Dec 29.

PMID:
22207682
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Effect of erythropoietin on hepcidin, DMT1 with IRE, and hephaestin gene expression in duodenum of rats.

Kong WN, Chang YZ, Wang SM, Zhai XL, Shang JX, Li LX, Duan XL.

J Gastroenterol. 2008;43(2):136-43. doi: 10.1007/s00535-007-2138-5. Epub 2008 Feb 29.

PMID:
18306987
[PubMed - indexed for MEDLINE]
16.

Physiological focus on the erythropoietin-hepcidin-ferroportin axis.

D'Anna MC, Roque ME.

Can J Physiol Pharmacol. 2013 May;91(5):338-45. doi: 10.1139/cjpp-2012-0214. Epub 2013 Mar 19.

PMID:
23656253
[PubMed - indexed for MEDLINE]
17.

Adaptation of iron transport and metabolism to acute high-altitude hypoxia in mountaineers.

Goetze O, Schmitt J, Spliethoff K, Theurl I, Weiss G, Swinkels DW, Tjalsma H, Maggiorini M, Krayenbühl P, Rau M, Fruehauf H, Wojtal KA, Müllhaupt B, Fried M, Gassmann M, Lutz T, Geier A.

Hepatology. 2013 Dec;58(6):2153-62. doi: 10.1002/hep.26581. Epub 2013 Oct 11.

PMID:
23787477
[PubMed - indexed for MEDLINE]
18.

Intestinal DMT1 cotransporter is down-regulated by hepcidin via proteasome internalization and degradation.

Brasse-Lagnel C, Karim Z, Letteron P, Bekri S, Bado A, Beaumont C.

Gastroenterology. 2011 Apr;140(4):1261-1271.e1. doi: 10.1053/j.gastro.2010.12.037. Epub 2011 Jan 1.

PMID:
21199652
[PubMed - indexed for MEDLINE]
19.

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.

Kautz L, Meynard D, Monnier A, Darnaud V, Bouvet R, Wang RH, Deng C, Vaulont S, Mosser J, Coppin H, Roth MP.

Blood. 2008 Aug 15;112(4):1503-9. doi: 10.1182/blood-2008-03-143354. Epub 2008 Jun 6.

PMID:
18539898
[PubMed - indexed for MEDLINE]
Free Article
20.

Iron regulation and erythropoiesis.

Nemeth E.

Curr Opin Hematol. 2008 May;15(3):169-75. doi: 10.1097/MOH.0b013e3282f73335. Review.

PMID:
18391780
[PubMed - indexed for MEDLINE]

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