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Results: 1 to 20 of 111

1.

Consequences of the combined loss of BOK and BAK or BOK and BAX.

Ke F, Bouillet P, Kaufmann T, Strasser A, Kerr J, Voss AK.

Cell Death Dis. 2013 Jun 6;4:e650. doi: 10.1038/cddis.2013.176.

PMID:
23744350
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice.

Ke F, Voss A, Kerr JB, O'Reilly LA, Tai L, Echeverry N, Bouillet P, Strasser A, Kaufmann T.

Cell Death Differ. 2012 Jun;19(6):915-25. doi: 10.1038/cdd.2011.210. Epub 2012 Jan 27. Erratum in: Cell Death Differ. 2013 Jan;20(1):183.

PMID:
22281706
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis.

Hutcheson J, Scatizzi JC, Bickel E, Brown NJ, Bouillet P, Strasser A, Perlman H.

J Exp Med. 2005 Jun 20;201(12):1949-60.

PMID:
15967824
[PubMed - indexed for MEDLINE]
Free PMC Article
4.
5.

Intracellular localization of the BCL-2 family member BOK and functional implications.

Echeverry N, Bachmann D, Ke F, Strasser A, Simon HU, Kaufmann T.

Cell Death Differ. 2013 Jun;20(6):785-99. doi: 10.1038/cdd.2013.10. Epub 2013 Feb 22.

PMID:
23429263
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.

Hikita H, Takehara T, Kodama T, Shimizu S, Shigekawa M, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Shimizu S, Tsujimoto Y, Hayashi N.

Hepatology. 2011 Jul;54(1):240-51. doi: 10.1002/hep.24305. Epub 2011 Apr 11.

PMID:
21425311
[PubMed - indexed for MEDLINE]
7.

Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members.

Hsu SY, Kaipia A, McGee E, Lomeli M, Hsueh AJ.

Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12401-6.

PMID:
9356461
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Proapoptotic bcl-2 family members, Bax and Bak, are essential for developmental photoreceptor apoptosis.

Hahn P, Lindsten T, Ying GS, Bennett J, Milam AH, Thompson CB, Dunaief JL.

Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3598-605.

PMID:
12882813
[PubMed - indexed for MEDLINE]
Free Article
9.

Pro-apoptotic Bax is the major and Bak an auxiliary effector in cytokine deprivation-induced mast cell apoptosis.

Karlberg M, Ekoff M, Labi V, Strasser A, Huang D, Nilsson G.

Cell Death Dis. 2010 May 13;1:e43. doi: 10.1038/cddis.2010.20.

PMID:
21364649
[PubMed - indexed for MEDLINE]
Free PMC Article
10.
11.

Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule-specific knockout mouse models.

Wei Q, Dong G, Chen JK, Ramesh G, Dong Z.

Kidney Int. 2013 Jul;84(1):138-48. doi: 10.1038/ki.2013.68. Epub 2013 Mar 6.

PMID:
23466994
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins.

Brooks C, Wei Q, Feng L, Dong G, Tao Y, Mei L, Xie ZJ, Dong Z.

Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11649-54. Epub 2007 Jul 2.

PMID:
17606912
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.

Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, Ma A, Golden JA, Evan G, Korsmeyer SJ, MacGregor GR, Thompson CB.

Mol Cell. 2000 Dec;6(6):1389-99.

PMID:
11163212
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.

Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.

Cancer Res. 2003 Apr 1;63(7):1712-21.

PMID:
12670926
[PubMed - indexed for MEDLINE]
Free Article
15.

Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonial and spermatocyte apoptosis in the testis.

Yan W, Samson M, Jégou B, Toppari J.

Mol Endocrinol. 2000 May;14(5):682-99.

PMID:
10809232
[PubMed - indexed for MEDLINE]
16.

Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1.

Du X, Youle RJ, FitzGerald DJ, Pastan I.

Mol Cell Biol. 2010 Jul;30(14):3444-52. doi: 10.1128/MCB.00813-09. Epub 2010 May 10.

PMID:
20457813
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.

Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.

J Biol Chem. 2011 Mar 18;286(11):9382-92. doi: 10.1074/jbc.M110.203638. Epub 2010 Dec 9.

PMID:
21148306
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Bax deficiency promotes an up-regulation of Bim(EL) and Bak during striatal and cortical postnatal development, and after excitotoxic injury.

Gavaldà N, Pérez-Navarro E, García-Martínez JM, Marco S, Benito A, Alberch J.

Mol Cell Neurosci. 2008 Apr;37(4):663-72. doi: 10.1016/j.mcn.2007.12.013. Epub 2007 Dec 15.

PMID:
18272391
[PubMed - indexed for MEDLINE]
19.

Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak.

Wang C, Youle RJ.

Oncogene. 2012 Jun 28;31(26):3177-89. doi: 10.1038/onc.2011.497. Epub 2011 Nov 7.

PMID:
22056880
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis.

Siskind LJ, Mullen TD, Romero Rosales K, Clarke CJ, Hernandez-Corbacho MJ, Edinger AL, Obeid LM.

J Biol Chem. 2010 Apr 16;285(16):11818-26. doi: 10.1074/jbc.M109.078121. Epub 2010 Feb 18.

PMID:
20172858
[PubMed - indexed for MEDLINE]
Free PMC Article

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