Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 374

1.

Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine.

Xie X, Tang B, Zhou J, Gao Q, Zhang P.

Oncol Rep. 2013 Aug;30(2):773-82. doi: 10.3892/or.2013.2520. Epub 2013 Jun 5.

PMID:
23743572
[PubMed - indexed for MEDLINE]
2.

Reversal effect of PI3-K inhibitor LY294002 on P-glycoprotein-mediated multidrug resistance of human leukemia cell line K562/DNR and gastric cancer cell line SGC7901/ADR.

Zhang Y, Qu XJ, Liu YP, Yang XH, Hou KZ, Teng YE, Zhang JD.

Ai Zheng. 2009 Feb;28(2):97-9. Epub 2009 Feb 23.

PMID:
19550116
[PubMed - indexed for MEDLINE]
3.

LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells.

Shin JY, Kim JO, Lee SK, Chae HS, Kang JH.

BMC Cancer. 2010 Aug 13;10:425. doi: 10.1186/1471-2407-10-425.

PMID:
20704765
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Phosphatidylinositol 3-kinase inhibitor LY294002 suppresses proliferation and sensitizes doxorubicin chemotherapy in bladder cancer cells.

Wu D, Tao J, Xu B, Qing W, Li P, Lu Q, Zhang W.

Urol Int. 2011;87(1):105-13. doi: 10.1159/000322849. Epub 2011 May 18.

PMID:
21597260
[PubMed - indexed for MEDLINE]
5.

Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45.

Osaki M, Kase S, Adachi K, Takeda A, Hashimoto K, Ito H.

J Cancer Res Clin Oncol. 2004 Jan;130(1):8-14. Epub 2003 Nov 7.

PMID:
14605879
[PubMed - indexed for MEDLINE]
6.

LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance.

Barancík M, Bohácová V, Sedlák J, Sulová Z, Breier A.

Eur J Pharm Sci. 2006 Dec;29(5):426-34. Epub 2006 Aug 22.

PMID:
17010577
[PubMed - indexed for MEDLINE]
7.

Blocking of PI3K/AKT induces apoptosis by its effect on NF-κB activity in gastric carcinoma cell line SGC7901.

Chao X, Zao J, Xiao-Yi G, Li-Jun M, Tao S.

Biomed Pharmacother. 2010 Nov;64(9):600-4. doi: 10.1016/j.biopha.2010.08.008. Epub 2010 Sep 23.

PMID:
20947290
[PubMed - indexed for MEDLINE]
8.

LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells.

Li C, Liu VW, Chan DW, Yao KM, Ngan HY.

Int J Gynecol Cancer. 2012 Jan;22(1):15-22. doi: 10.1097/IGC.0b013e3182322834.

PMID:
22080879
[PubMed - indexed for MEDLINE]
9.

[Reversal effect of PI-3K/Akt pathway inhibitor LY294002 on multidrug resistance of ovarian cancer cell line A2780/Taxol].

Shi XY, Cai XJ, Lei JX, Cao FJ, Pan DF, Chen P.

Ai Zheng. 2008 Apr;27(4):343-7. Chinese.

PMID:
18423117
[PubMed - indexed for MEDLINE]
10.

[Combined inhibition of PI3K and MEK has synergistic inhibitory effect on the proliferation of cisplatin-resistant ovarian cancer cells].

Liu Y, Chen X, Luo Z.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014 Jun;30(6):592-6. Chinese.

PMID:
24909280
[PubMed - indexed for MEDLINE]
11.
12.

[Effects of PD98059 and LY294002 on subcutaneous xenograft of human endometrial carcinoma in nude mice].

Guo RX, Zhang RF, Wang XY, Shi HR, Qiao YH.

Zhonghua Fu Chan Ke Za Zhi. 2011 Jun;46(6):446-52. Chinese.

PMID:
21781587
[PubMed - indexed for MEDLINE]
13.

Role of phosphatidylinositol 3'-kinase/AKT pathway in diffuse large B-cell lymphoma survival.

Uddin S, Hussain AR, Siraj AK, Manogaran PS, Al-Jomah NA, Moorji A, Atizado V, Al-Dayel F, Belgaumi A, El-Solh H, Ezzat A, Bavi P, Al-Kuraya KS.

Blood. 2006 Dec 15;108(13):4178-86. Epub 2006 Aug 31.

PMID:
16946303
[PubMed - indexed for MEDLINE]
Free Article
14.

Programmed cell death 4 (PDCD4) enhances the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by inhibiting the PI3K/Akt signaling pathway.

Wang WQ, Zhang H, Wang HB, Sun YG, Peng ZH, Zhou G, Yang SM, Wang RQ, Fang DC.

Mol Diagn Ther. 2010 Jun 1;14(3):155-61. doi: 10.2165/11536340-000000000-00000.

PMID:
20560677
[PubMed - indexed for MEDLINE]
15.

PI3K/Akt is involved in bufalin-induced apoptosis in gastric cancer cells.

Li D, Qu X, Hou K, Zhang Y, Dong Q, Teng Y, Zhang J, Liu Y.

Anticancer Drugs. 2009 Jan;20(1):59-64. doi: 10.1097/CAD.0b013e3283160fd6.

PMID:
19343001
[PubMed - indexed for MEDLINE]
16.
17.

Inhibition of PI3K/Akt partially leads to the inhibition of PrP(C)-induced drug resistance in gastric cancer cells.

Liang J, Ge F, Guo C, Luo G, Wang X, Han G, Zhang D, Wang J, Li K, Pan Y, Yao L, Yin Z, Guo X, Wu K, Ding J, Fan D.

FEBS J. 2009 Feb;276(3):685-94. doi: 10.1111/j.1742-4658.2008.06816.x.

PMID:
19143835
[PubMed - indexed for MEDLINE]
18.

Dual blockade of phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer.

Xu R, Nakano K, Iwasaki H, Kumagai M, Wakabayashi R, Yamasaki A, Suzuki H, Mibu R, Onishi H, Katano M.

Cancer Lett. 2011 Jul 28;306(2):151-60. doi: 10.1016/j.canlet.2011.02.042. Epub 2011 Mar 22.

PMID:
21429662
[PubMed - indexed for MEDLINE]
19.

Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma.

Kobayashi I, Semba S, Matsuda Y, Kuroda Y, Yokozaki H.

Pathobiology. 2006;73(1):8-17.

PMID:
16785763
[PubMed - indexed for MEDLINE]
20.

Response of non-small cell lung cancer cells to the inhibitors of phosphatidylinositol 3-kinase/Akt- and MAPK kinase 4/c-Jun NH2-terminal kinase pathways: an effective therapeutic strategy for lung cancer.

Lee HY, Oh SH, Suh YA, Baek JH, Papadimitrakopoulou V, Huang S, Hong WK.

Clin Cancer Res. 2005 Aug 15;11(16):6065-74.

PMID:
16115952
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk