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Results: 1 to 20 of 98

1.

Pyrrolidine dithiocarbamate inhibits herpes simplex virus 1 and 2 replication, and its activity may be mediated through dysregulation of the ubiquitin-proteasome system.

Qiu M, Chen Y, Cheng L, Chu Y, Song HY, Wu ZW.

J Virol. 2013 Aug;87(15):8675-86. doi: 10.1128/JVI.00869-13. Epub 2013 Jun 5.

PMID:
23740985
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Zinc ionophores pyrithione inhibits herpes simplex virus replication through interfering with proteasome function and NF-κB activation.

Qiu M, Chen Y, Chu Y, Song S, Yang N, Gao J, Wu Z.

Antiviral Res. 2013 Oct;100(1):44-53. doi: 10.1016/j.antiviral.2013.07.001. Epub 2013 Jul 15.

PMID:
23867132
[PubMed - indexed for MEDLINE]
3.

Pyrrolidine dithiocarbamate reduces coxsackievirus B3 replication through inhibition of the ubiquitin-proteasome pathway.

Si X, McManus BM, Zhang J, Yuan J, Cheung C, Esfandiarei M, Suarez A, Morgan A, Luo H.

J Virol. 2005 Jul;79(13):8014-23.

PMID:
15956547
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells.

Faith SA, Sweet TJ, Bailey E, Booth T, Docherty JJ.

Antiviral Res. 2006 Dec;72(3):242-51. Epub 2006 Jul 14.

PMID:
16876885
[PubMed - indexed for MEDLINE]
5.

PDTC inhibits picornavirus polyprotein processing and RNA replication by transporting zinc ions into cells.

Lanke K, Krenn BM, Melchers WJ, Seipelt J, van Kuppeveld FJ.

J Gen Virol. 2007 Apr;88(Pt 4):1206-17.

PMID:
17374764
[PubMed - indexed for MEDLINE]
Free Article
6.

Antiviral activity of proteasome inhibitors in herpes simplex virus-1 infection: role of nuclear factor-kappaB.

La Frazia S, Amici C, Santoro MG.

Antivir Ther. 2006;11(8):995-1004.

PMID:
17302369
[PubMed - indexed for MEDLINE]
7.

Pyrrolidine dithiocarbamate-induced neuronal cell death is mediated by Akt, casein kinase 2, c-Jun N-terminal kinase, and IkappaB kinase in embryonic hippocampal progenitor cells.

Min YK, Park JH, Chong SA, Kim YS, Ahn YS, Seo JT, Bae YS, Chung KC.

J Neurosci Res. 2003 Mar 1;71(5):689-700.

PMID:
12584727
[PubMed - indexed for MEDLINE]
8.

Novel biphasic effect of pyrrolidine dithiocarbamate on neuronal cell viability is mediated by the differential regulation of intracellular zinc and copper ion levels, NF-kappaB, and MAP kinases.

Chung KC, Park JH, Kim CH, Lee HW, Sato N, Uchiyama Y, Ahn YS.

J Neurosci Res. 2000 Jan 1;59(1):117-25.

PMID:
10658192
[PubMed - indexed for MEDLINE]
9.

Inhibition of polyprotein processing and RNA replication of human rhinovirus by pyrrolidine dithiocarbamate involves metal ions.

Krenn BM, Holzer B, Gaudernak E, Triendl A, van Kuppeveld FJ, Seipelt J.

J Virol. 2005 Nov;79(22):13892-9.

PMID:
16254325
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Therapy of experimental influenza virus infection with pyrrolidine dithiocarbamate.

Wiesener N, Zimmer C, Jarasch-Althof N, Wutzler P, Henke A.

Med Microbiol Immunol. 2011 May;200(2):115-26. doi: 10.1007/s00430-010-0182-x. Epub 2010 Dec 21.

PMID:
21174118
[PubMed - indexed for MEDLINE]
11.

Zinc is required in pyrrolidine dithiocarbamate inhibition of NF-kappaB activation.

Kim CH, Kim JH, Hsu CY, Ahn YS.

FEBS Lett. 1999 Apr 16;449(1):28-32.

PMID:
10225421
[PubMed - indexed for MEDLINE]
Free Article
12.

Effect of antioxidants on apoptosis induced by influenza virus infection: inhibition of viral gene replication and transcription with pyrrolidine dithiocarbamate.

Uchide N, Ohyama K, Bessho T, Yuan B, Yamakawa T.

Antiviral Res. 2002 Dec;56(3):207-17.

PMID:
12406505
[PubMed - indexed for MEDLINE]
13.

Antiviral effects of pyrrolidine dithiocarbamate on human rhinoviruses.

Gaudernak E, Seipelt J, Triendl A, Grassauer A, Kuechler E.

J Virol. 2002 Jun;76(12):6004-15.

PMID:
12021333
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Pyrrolidine dithiocarbamate inhibits serum-induced NF-kappaB activation and induces apoptosis in ROS 17/2.8 osteoblasts.

Chae H, Chae S, Park N, Bang B, Cho S, Kim J, Kim H, Kim H, Lee Z, Kim H.

Int Immunopharmacol. 2001 Feb;1(2):255-63.

PMID:
11360927
[PubMed - indexed for MEDLINE]
15.

Dysregulation of the ubiquitin-proteasome system by curcumin suppresses coxsackievirus B3 replication.

Si X, Wang Y, Wong J, Zhang J, McManus BM, Luo H.

J Virol. 2007 Apr;81(7):3142-50. Epub 2007 Jan 17.

PMID:
17229707
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Resveratrol inhibition of herpes simplex virus replication.

Docherty JJ, Fu MM, Stiffler BS, Limperos RJ, Pokabla CM, DeLucia AL.

Antiviral Res. 1999 Oct;43(3):145-55.

PMID:
10551373
[PubMed - indexed for MEDLINE]
17.

Pyrrolidine dithiocarbamate and zinc inhibit proteasome-dependent proteolysis.

Kim I, Kim CH, Kim JH, Lee J, Choi JJ, Chen ZA, Lee MG, Chung KC, Hsu CY, Ahn YS.

Exp Cell Res. 2004 Aug 1;298(1):229-38.

PMID:
15242777
[PubMed - indexed for MEDLINE]
18.

Inhibition of virus-encoded thymidine kinase suppresses herpes simplex virus replication in vitro and in vivo.

Watkins AM, Dunford PJ, Moffatt AM, Wong-Kai-In P, Holland MJ, Pole DS, Thomas GM, Martin J, Roberts NA, Mulqueen MJ.

Antivir Chem Chemother. 1998 Jan;9(1):9-18.

PMID:
9875372
[PubMed - indexed for MEDLINE]
19.

Evidence of dual sites of action of dendrimers: SPL-2999 inhibits both virus entry and late stages of herpes simplex virus replication.

Gong Y, Matthews B, Cheung D, Tam T, Gadawski I, Leung D, Holan G, Raff J, Sacks S.

Antiviral Res. 2002 Aug;55(2):319-29.

PMID:
12103432
[PubMed - indexed for MEDLINE]
20.

Pyrrolidine dithiocarbamate-induced apoptosis depends on cell type, density, and the presence of Cu(2+) and Zn(2+).

Erl W, Weber C, Hansson GK.

Am J Physiol Cell Physiol. 2000 Jun;278(6):C1116-25.

PMID:
10837339
[PubMed - indexed for MEDLINE]
Free Article
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