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Items: 1 to 20 of 86

1.

The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project.

Medway C, Combarros O, Cortina-Borja M, Butler HT, Ibrahim-Verbaas CA, de Bruijn RF, Koudstaal PJ, van Duijn CM, Ikram MA, Mateo I, Sánchez-Juan P, Lehmann MG, Heun R, Kölsch H, Deloukas P, Hammond N, Coto E, Alvarez V, Kehoe PG, Barber R, Wilcock GK, Brown K, Belbin O, Warden DR, Smith AD, Morgan K, Lehmann DJ.

Eur J Hum Genet. 2014 Feb;22(2):216-20. doi: 10.1038/ejhg.2013.116. Epub 2013 Jun 5.

2.

Aromatase and interleukin-10 genetic variants interactively modulate Alzheimer's disease risk.

Combarros O, Sánchez-Juan P, Riancho JA, Mateo I, Rodríguez-Rodríguez E, Infante J, García-Gorostiaga I, Vázquez-Higuera JL, Berciano J.

J Neural Transm (Vienna). 2008 Jun;115(6):863-7. doi: 10.1007/s00702-008-0028-5. Epub 2008 Feb 26.

PMID:
18299793
3.

Association of the aromatase gene with Alzheimer's disease in women.

Butler HT, Warden DR, Hogervorst E, Ragoussis J, Smith AD, Lehmann DJ.

Neurosci Lett. 2010 Jan 14;468(3):202-6. doi: 10.1016/j.neulet.2009.10.089. Epub 2009 Oct 30.

PMID:
19879925
4.

Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease.

Combarros O, van Duijn CM, Hammond N, Belbin O, Arias-Vásquez A, Cortina-Borja M, Lehmann MG, Aulchenko YS, Schuur M, Kölsch H, Heun R, Wilcock GK, Brown K, Kehoe PG, Harrison R, Coto E, Alvarez V, Deloukas P, Mateo I, Gwilliam R, Morgan K, Warden DR, Smith AD, Lehmann DJ.

J Neuroinflammation. 2009 Aug 23;6:22. doi: 10.1186/1742-2094-6-22.

5.

Aromatase enzyme and Alzheimer's disease.

Hiltunen M, Iivonen S, Soininen H.

Minerva Endocrinol. 2006 Mar;31(1):61-73. Review.

PMID:
16498364
6.

Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease.

Iivonen S, Corder E, Lehtovirta M, Helisalmi S, Mannermaa A, Vepsäläinen S, Hänninen T, Soininen H, Hiltunen M.

Neurology. 2004 Apr 13;62(7):1170-6.

PMID:
15079018
7.

Interleukin-10 and interleukin-6 gene polymorphisms as risk factors for Alzheimer's disease.

Arosio B, Trabattoni D, Galimberti L, Bucciarelli P, Fasano F, Calabresi C, Cazzullo CL, Vergani C, Annoni G, Clerici M.

Neurobiol Aging. 2004 Sep;25(8):1009-15.

PMID:
15212825
8.

The association between promoter polymorphism of the interleukin-10 gene and Alzheimer's disease.

Ma SL, Tang NL, Lam LC, Chiu HF.

Neurobiol Aging. 2005 Jul;26(7):1005-10. Epub 2004 Nov 23.

PMID:
15748779
9.

Association of IL10 promoter polymorphism in Italian Alzheimer's disease.

Bagnoli S, Cellini E, Tedde A, Nacmias B, Piacentini S, Bessi V, Bracco L, Sorbi S.

Neurosci Lett. 2007 May 18;418(3):262-5. Epub 2007 Mar 19.

PMID:
17420099
10.

The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project.

Combarros O, Warden DR, Hammond N, Cortina-Borja M, Belbin O, Lehmann MG, Wilcock GK, Brown K, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Gwilliam R, Heun R, Kölsch H, Mateo I, Oulhaj A, Arias-Vásquez A, Schuur M, Aulchenko YS, Ikram MA, Breteler MM, van Duijn CM, Morgan K, Smith AD, Lehmann DJ.

BMC Med Genet. 2010 Nov 11;11:162. doi: 10.1186/1471-2350-11-162.

11.

Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimer's disease in women.

Corbo RM, Gambina G, Ulizzi L, Moretto G, Scacchi R.

Dement Geriatr Cogn Disord. 2009;27(6):513-8. doi: 10.1159/000221832. Epub 2009 May 29.

PMID:
19478482
12.

Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease.

Bullock JM, Medway C, Cortina-Borja M, Turton JC, Prince JA, Ibrahim-Verbaas CA, Schuur M, Breteler MM, van Duijn CM, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Hammond N, Combarros O, Mateo I, Warden DR, Lehmann MG, Belbin O, Brown K, Wilcock GK, Heun R, Kölsch H, Smith AD, Lehmann DJ, Morgan K.

Neurobiol Aging. 2013 Apr;34(4):1309.e1-7. doi: 10.1016/j.neurobiolaging.2012.08.010. Epub 2012 Oct 1.

PMID:
23036584
13.

Aromatase variants modify risk for Alzheimer's disease in a multiethnic female cohort.

Janicki SC, Park N, Cheng R, Schupf N, Clark LN, Lee JH.

Dement Geriatr Cogn Disord. 2013;35(5-6):340-6. doi: 10.1159/000343074. Epub 2013 Apr 18.

14.

CYP19 haplotypes increase risk for Alzheimer's disease.

Huang R, Poduslo SE.

J Med Genet. 2006 Aug;43(8):e42.

15.

The combinations of TNFalpha-308 and IL-6 -174 or IL-10 -1082 genes polymorphisms suggest an association with susceptibility to sporadic late-onset Alzheimer's disease.

Vural P, Değirmencioğlu S, Parildar-Karpuzoğlu H, Doğru-Abbasoğlu S, Hanagasi HA, Karadağ B, Gürvit H, Emre M, Uysal M.

Acta Neurol Scand. 2009 Dec;120(6):396-401. doi: 10.1111/j.1600-0404.2009.01230.x. Epub 2009 Sep 10.

PMID:
19744138
16.

Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project.

Kölsch H, Lehmann DJ, Ibrahim-Verbaas CA, Combarros O, van Duijn CM, Hammond N, Belbin O, Cortina-Borja M, Lehmann MG, Aulchenko YS, Schuur M, Breteler M, Wilcock GK, Brown K, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Mateo I, Maier W, Morgan K, Warden DR, Smith AD, Heun R.

J Neural Transm (Vienna). 2012 Apr;119(4):473-9. doi: 10.1007/s00702-011-0732-4. Epub 2011 Nov 8.

PMID:
22065208
17.

Interaction between CYP19 aromatase and butyrylcholinesterase genes increases Alzheimer's disease risk.

Combarros O, Riancho JA, Infante J, Sañudo C, Llorca J, Zarrabeitia MT, Berciano J.

Dement Geriatr Cogn Disord. 2005;20(2-3):153-7. Epub 2005 Jul 13.

PMID:
16020944
18.

Common variations in estrogen-related genes are associated with severe large-joint osteoarthritis: a multicenter genetic and functional study.

Riancho JA, García-Ibarbia C, Gravani A, Raine EV, Rodríguez-Fontenla C, Soto-Hermida A, Rego-Perez I, Dodd AW, Gómez-Reino JJ, Zarrabeitia MT, Garcés CM, Carr A, Blanco F, González A, Loughlin J.

Osteoarthritis Cartilage. 2010 Jul;18(7):927-33. doi: 10.1016/j.joca.2010.04.002. Epub 2010 Apr 22.

19.

Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease.

Chen SY, Chen TF, Lai LC, Chen JH, Sun Y, Wen LL, Yip PK, Chu YM, Chen YC.

J Neuroinflammation. 2012 Jan 24;9:21. doi: 10.1186/1742-2094-9-21.

20.

Interactions between PPAR-α and inflammation-related cytokine genes on the development of Alzheimer's disease, observed by the Epistasis Project.

Heun R, Kölsch H, Ibrahim-Verbaas CA, Combarros O, Aulchenko YS, Breteler M, Schuur M, van Duijn CM, Hammond N, Belbin O, Cortina-Borja M, Wilcock GK, Brown K, Barber R, Kehoe PG, Coto E, Alvarez V, Lehmann MG, Deloukas P, Mateo I, Morgan K, Warden DR, Smith AD, Lehmann DJ.

Int J Mol Epidemiol Genet. 2012;3(1):39-47. Epub 2012 Feb 23.

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