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Items: 1 to 20 of 105

1.

Identification of driver genes in hepatocellular carcinoma by exome sequencing.

Cleary SP, Jeck WR, Zhao X, Chen K, Selitsky SR, Savich GL, Tan TX, Wu MC, Getz G, Lawrence MS, Parker JS, Li J, Powers S, Kim H, Fischer S, Guindi M, Ghanekar A, Chiang DY.

Hepatology. 2013 Nov;58(5):1693-702. doi: 10.1002/hep.26540. Epub 2013 Sep 24.

2.

The genomic landscape of hepatoblastoma and their progenies with HCC-like features.

Eichenmüller M, Trippel F, Kreuder M, Beck A, Schwarzmayr T, Häberle B, Cairo S, Leuschner I, von Schweinitz D, Strom TM, Kappler R.

J Hepatol. 2014 Dec;61(6):1312-20. doi: 10.1016/j.jhep.2014.08.009. Epub 2014 Aug 15.

PMID:
25135868
3.

Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma.

Gu DL, Chen YH, Shih JH, Lin CH, Jou YS, Chen CF.

World J Gastroenterol. 2013 Dec 21;19(47):8873-9. doi: 10.3748/wjg.v19.i47.8873. Review.

4.

Paediatric hepatocellular carcinoma due to somatic CTNNB1 and NFE2L2 mutations in the setting of inherited bi-allelic ABCB11 mutations.

Vilarinho S, Erson-Omay EZ, Harmanci AS, Morotti R, Carrion-Grant G, Baranoski J, Knisely AS, Ekong U, Emre S, Yasuno K, Bilguvar K, Günel M.

J Hepatol. 2014 Nov;61(5):1178-83. doi: 10.1016/j.jhep.2014.07.003. Epub 2014 Jul 10.

PMID:
25016225
5.

Leptin receptor somatic mutations are frequent in HCV-infected cirrhotic liver and associated with hepatocellular carcinoma.

Ikeda A, Shimizu T, Matsumoto Y, Fujii Y, Eso Y, Inuzuka T, Mizuguchi A, Shimizu K, Hatano E, Uemoto S, Chiba T, Marusawa H.

Gastroenterology. 2014 Jan;146(1):222-32.e35. doi: 10.1053/j.gastro.2013.09.025. Epub 2013 Sep 19.

PMID:
24055508
6.

Profiling of exome mutations associated with progression of HBV-related hepatocellular carcinoma.

Woo HG, Kim SS, Cho H, Kwon SM, Cho HJ, Ahn SJ, Park ES, Lee JS, Cho SW, Cheong JY.

PLoS One. 2014 Dec 18;9(12):e115152. doi: 10.1371/journal.pone.0115152. eCollection 2014.

7.

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma.

Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, Maad IB, Calderaro J, Bioulac-Sage P, Letexier M, Degos F, Clément B, Balabaud C, Chevet E, Laurent A, Couchy G, Letouzé E, Calvo F, Zucman-Rossi J.

Nat Genet. 2012 May 6;44(6):694-8. doi: 10.1038/ng.2256.

8.

Next generation sequencing reveals genetic landscape of hepatocellular carcinomas.

Li S, Mao M.

Cancer Lett. 2013 Nov 1;340(2):247-53. doi: 10.1016/j.canlet.2012.09.027. Epub 2012 Oct 12. Review.

PMID:
23063663
9.

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.

Schulze K, Imbeaud S, Letouzé E, Alexandrov LB, Calderaro J, Rebouissou S, Couchy G, Meiller C, Shinde J, Soysouvanh F, Calatayud AL, Pinyol R, Pelletier L, Balabaud C, Laurent A, Blanc JF, Mazzaferro V, Calvo F, Villanueva A, Nault JC, Bioulac-Sage P, Stratton MR, Llovet JM, Zucman-Rossi J.

Nat Genet. 2015 May;47(5):505-11. doi: 10.1038/ng.3252. Epub 2015 Mar 30.

10.

Exome capture sequencing reveals new insights into hepatitis B virus-induced hepatocellular carcinoma at the early stage of tumorigenesis.

Chen Y, Wang L, Xu H, Liu X, Zhao Y.

Oncol Rep. 2013 Oct;30(4):1906-12. doi: 10.3892/or.2013.2652. Epub 2013 Aug 2.

PMID:
23912677
11.

Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma.

Huang J, Deng Q, Wang Q, Li KY, Dai JH, Li N, Zhu ZD, Zhou B, Liu XY, Liu RF, Fei QL, Chen H, Cai B, Zhou B, Xiao HS, Qin LX, Han ZG.

Nat Genet. 2012 Oct;44(10):1117-21. doi: 10.1038/ng.2391. Epub 2012 Aug 26.

PMID:
22922871
12.

Whole-exome sequencing characterizes the landscape of somatic mutations and copy number alterations in adrenocortical carcinoma.

Juhlin CC, Goh G, Healy JM, Fonseca AL, Scholl UI, Stenman A, Kunstman JW, Brown TC, Overton JD, Mane SM, Nelson-Williams C, Bäckdahl M, Suttorp AC, Haase M, Choi M, Schlessinger J, Rimm DL, Höög A, Prasad ML, Korah R, Larsson C, Lifton RP, Carling T.

J Clin Endocrinol Metab. 2015 Mar;100(3):E493-502. doi: 10.1210/jc.2014-3282. Epub 2014 Dec 9.

PMID:
25490274
13.

Targeted and exome sequencing identified somatic mutations in hepatocellular carcinoma.

Hirotsu Y, Zheng TH, Amemiya K, Mochizuki H, Guleng B, Omata M.

Hepatol Res. 2016 Feb 5. doi: 10.1111/hepr.12663. [Epub ahead of print]

PMID:
26850916
14.

Somatic changes in primary liver cancer in Russia: a pilot study.

Kalinina O, Marchio A, Urbanskii AI, Tarkova AB, Rebbani K, Granov DA, Dejean A, Generalov MI, Pineau P.

Mutat Res. 2013 Aug 15;755(2):90-9. doi: 10.1016/j.mrgentox.2013.06.019. Epub 2013 Jul 2.

PMID:
23830926
15.

Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.

Kim Y, Hammerman PS, Kim J, Yoon JA, Lee Y, Sun JM, Wilkerson MD, Pedamallu CS, Cibulskis K, Yoo YK, Lawrence MS, Stojanov P, Carter SL, McKenna A, Stewart C, Sivachenko AY, Oh IJ, Kim HK, Choi YS, Kim K, Shim YM, Kim KS, Song SY, Na KJ, Choi YL, Hayes DN, Kim J, Cho S, Kim YC, Ahn JS, Ahn MJ, Getz G, Meyerson M, Park K.

J Clin Oncol. 2014 Jan 10;32(2):121-8. doi: 10.1200/JCO.2013.50.8556. Epub 2013 Dec 9.

16.

Recent advancements in comprehensive genetic analyses for human hepatocellular carcinoma.

Nishida N, Kudo M.

Oncology. 2013;84 Suppl 1:93-7. doi: 10.1159/000345897. Epub 2013 Feb 20. Review.

PMID:
23428866
17.

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.

Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, Nguyen HH, Aoki M, Hosono N, Kubo M, Miya F, Arai Y, Takahashi H, Shirakihara T, Nagasaki M, Shibuya T, Nakano K, Watanabe-Makino K, Tanaka H, Nakamura H, Kusuda J, Ojima H, Shimada K, Okusaka T, Ueno M, Shigekawa Y, Kawakami Y, Arihiro K, Ohdan H, Gotoh K, Ishikawa O, Ariizumi S, Yamamoto M, Yamada T, Chayama K, Kosuge T, Yamaue H, Kamatani N, Miyano S, Nakagama H, Nakamura Y, Tsunoda T, Shibata T, Nakagawa H.

Nat Genet. 2012 May 27;44(7):760-4. doi: 10.1038/ng.2291.

PMID:
22634756
18.

Integrated analysis of mutation data from various sources identifies key genes and signaling pathways in hepatocellular carcinoma.

Zhang Y, Qiu Z, Wei L, Tang R, Lian B, Zhao Y, He X, Xie L.

PLoS One. 2014 Jul 2;9(7):e100854. doi: 10.1371/journal.pone.0100854. eCollection 2014.

19.

Correlation of TP53 mutations with HCV positivity in hepatocarcinogenesis: identification of a novel TP53 microindel in hepatocellular carcinoma with HCV infection.

Long J, Wang Y, Li M, Tong WM, Jia JD, Huang J.

Oncol Rep. 2013 Jul;30(1):119-24. doi: 10.3892/or.2013.2430. Epub 2013 Apr 26.

PMID:
23624687
20.

Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections.

Tornesello ML, Buonaguro L, Tatangelo F, Botti G, Izzo F, Buonaguro FM.

Genomics. 2013 Aug;102(2):74-83. doi: 10.1016/j.ygeno.2013.04.001. Epub 2013 Apr 11. Review.

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